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Ophthalmology General

Retinal and Choroidal Changes Following Implantable Collamer Lens V4c Implantation in High Myopia Patients-A 1-Year Follow-Up Study.

Oct 16, 2023

This prospective study aimed to evaluate the impact of Visian Implantable Collamer Lens (ICL) V4c implantation on retinal and choroidal morphology in patients with high myopia. A total of 97 eyes from...

Impact of Dry Eye Disease on the Uncorrected Distance Visual Acuity after Small Incision Lenticule Extraction.

Oct 16, 2023

The aim of this study was to explore the impact of dry eye disease (DED) on the uncorrected distance visual acuity (UDVA) and refractive status after small incision lenticule extraction (SMILE). This ...

Terahertz Attenuated Total Reflection Spectral Response and Signal Enhancement via Plasmonic Enhanced Sensor for Eye Drop Detection.

Oct 16, 2023

With chronic ocular diseases such as glaucoma and dry eye syndrome, patients have to apply eye drops over the long term. The therapeutic effects of eye drops depend on the amount of drug contained and...

5-Bromo-3,4-dihydroxybenzaldehyde stabilizes diabetic retinal neurovascular units by inhibiting the inflammatory microenvironment.

Oct 16, 2023

Diabetic retinopathy (DR) is a leading cause of blindness characterized by damage to the retinal neurovascular unit, which is caused by hyperglycemia-induced metabolic and inflammatory responses. 5-Br...

eIF4A3-mediated circEHMT1 regulation in retinal microvascular endothelial dysfunction in diabetic retinopathy.

Oct 16, 2023

Literature has reported that circular RNAs (circRNAs) are crucially associated with diabetic retinopathy (DR). Furthermore, circEHMT1 has been identified to maintain endothelial cell barrier function....

COG1410 regulates microglial states and protects retinal ganglion cells in retinal ischemia-reperfusion injury.

Oct 16, 2023

Progressive loss of retinal ganglion cells (RGCs) caused by retinal ischemia-reperfusion (IR) injury can lead to irreversible vision impairment, with neuroinflammatory responses playing an important r...

Early Outcomes of Combined Phacoemulsification and Ab Interno Tanito Microhook Trabeculotomy in Open Angle Glaucoma.

Oct 16, 2023

To study the early postoperative efficacy and safety of an Ab Interno microhook trabeculotomy (microLOT) combined with cataract surgery in patients with open angle glaucoma.This prospective, randomize...

Are isolated ocular motor nerve palsies in the elderly truly 'low risk' for abnormal neuro-imaging outcomes?

Oct 16, 2023

Neurologically isolated ocular motor nerve palsies often present a management dilemma. Neuroimaging is more likely to be offered to patients <50 years without coexisting ischaemic risk factors as t...

Ophthalmology Faculty Diversity Trends in the US.

Oct 16, 2023

Enhancing the diversity of ophthalmologists can potentially contribute to diminishing disparities in eye care.To investigate longitudinal trends in the representation of individuals underrepresented i...

Antioxidative effects of ghrelin on human trabecular meshwork cells.

Oct 09, 2023

Glaucoma is a group of neurodegenerative diseases characterized by loss of retinal ganglion cells and visual field defects and is one of the major causes of irreversible blindness worldwide. Primary o...

RBP3-retinopathy - inherited high myopia and retinal dystrophy: Genetic Characterization, Natural History, and Deep Phenotyping.

Oct 09, 2023

To examine the genetic and clinical features and the natural history of RBP3-associated retinopathy.Multi-center international, retrospective, case series.Three tertiary referral centers.Adults and ch...

Association between inflammatory cytokines and oxidative stress levels in aqueous humor with axial length in human myopia.

Oct 09, 2023

This study investigated the content of inflammatory cytokines and oxidative stress levels in the aqueous humor (AH) of patients with high myopia (HM) and explored the relationship between these factor...

[Efficacy evaluation of 0.05% cyclosporine A and 0.1% tacrolimus eye drops in the treatment of severe dry eye associated with chronic graft-versus-host disease].

Oct 09, 2023

To evaluate the effectiveness and safety of 0.05% cyclosporine A and 0.1% tacrolimus eye drops in treating severe dry eye associated with chronic graft-versus-host disease (cGVHD). This non-randomiz...

Ocular surface toxicities associated with modern anticancer therapies.

Oct 09, 2023

Cancer treatments have recently shifted from broad-spectrum cytotoxic therapies to more focused treatments, maximizing anti-cancerous activity while reducing toxicity to healthy cells. These modern an...

OCT-Angiography of deep and superficial retinal vascular density changes in diabetes without diabetic retinopathy.

Oct 09, 2023

To analyze the vascular density values (VD) in the superficial and the deep retinal network and in all perimacular sectors of diabetic eyes without clinical retinopathy, comparing them to that of heal...

GAMMA challenge: Glaucoma grAding from Multi-Modality imAges.

Oct 09, 2023

Glaucoma is a chronic neuro-degenerative condition that is one of the world's leading causes of irreversible but preventable blindness. The blindness is generally caused by the lack of timely detectio...

Accommodative-vergence disorders in a paediatric ophthalmology clinical setting in Argentina.

Oct 02, 2023

To determine the frequency of potential non-strabismic accommodative-vergence anomalies (NSAVA) and investigate associations between NSAVA, refractive errors and age among children attending a paediat...

Neurovascular coupling dysfunction in high myopia patients: evidence from a multi-modal magnetic resonance imaging analysis.

Oct 02, 2023

To investigate neurovascular coupling dysfunction in high myopia (HM) patients.A total of 37 HM patients and 36 healthy controls were included in this study. Degree centrality (DC), regional homogenei...

New insights into lacrimal gland anatomy using 7T MRI and electron microscopy: Relevance for lacrimal gland targeted therapies and bioengineering.

Oct 02, 2023

To study the tissue architecture, isthmus (connection between two lobes) of the lacrimal gland using preclinical 7T MRI in combination with histology and electron microscopy.Ten lacrimal glands from f...

Ocular toxicities of fibroblast growth factor receptor Inhibitors: A review.

Oct 02, 2023

Fibroblast growth factor receptor (FGFR) inhibitors are an emerging class of small molecule targeted cancer drugs with promising therapeutic possibilities for a wide variety of malignancies. While ocu...

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