Oct 09, 2023

Cancer treatments have recently shifted from broad-spectrum cytotoxic therapies to more focused treatments, maximizing anti-cancerous activity while reducing toxicity to healthy cells. These modern an...

Oct 09, 2023

To analyze the vascular density values (VD) in the superficial and the deep retinal network and in all perimacular sectors of diabetic eyes without clinical retinopathy, comparing them to that of heal...

Oct 09, 2023

Glaucoma is a chronic neuro-degenerative condition that is one of the world's leading causes of irreversible but preventable blindness. The blindness is generally caused by the lack of timely detectio...

Oct 02, 2023

To determine the frequency of potential non-strabismic accommodative-vergence anomalies (NSAVA) and investigate associations between NSAVA, refractive errors and age among children attending a paediat...

Oct 02, 2023

To investigate neurovascular coupling dysfunction in high myopia (HM) patients.A total of 37 HM patients and 36 healthy controls were included in this study. Degree centrality (DC), regional homogenei...

Oct 02, 2023

To study the tissue architecture, isthmus (connection between two lobes) of the lacrimal gland using preclinical 7T MRI in combination with histology and electron microscopy.Ten lacrimal glands from f...

Oct 02, 2023

Fibroblast growth factor receptor (FGFR) inhibitors are an emerging class of small molecule targeted cancer drugs with promising therapeutic possibilities for a wide variety of malignancies. While ocu...

Oct 02, 2023

Cyclic GMP-AMP (cGAMP) synthase (cGAS), a sensor of cytosolic DNA, recognizes cytoplasmic nucleic acids to activate the innate immune responses via generation of the second messenger cGAMP and subsequ...

Oct 02, 2023

Retinal ganglion cells, the neurons that die in glaucoma, are endowed with a high metabolism requiring optimal provision of oxygen and nutrients to sustain their activity. The timely regulation of blo...

Oct 02, 2023

Diseases leading to retinal cell loss can cause severe visual impairment and blindness. The lack of effective therapies to address retinal cell loss and the absence of intrinsic regeneration in the hu...

Oct 02, 2023

Private equity (PE) firms are increasingly acquiring ophthalmology practices; little is known of their influence on care utilization and spending. We studied changes in utilization and Medicare spendi...

Sep 25, 2023

This study aims to identify potential myopia biomarkers using machine learning algorithms, enhancing myopia diagnosis and prognosis prediction.GSE112155 and GSE15163 datasets from the GEO database wer...

Sep 25, 2023

The muscarinic cholinergic antagonist atropine is the most widely used pharmacological treatment for the visual disorder myopia (short-sightedness), the leading cause of low-vision worldwide. This stu...

Sep 25, 2023

The innate immune response is the main pathophysiological process of ocular surface diseases exposed to multiple environmental stresses. The epithelium is central to the innate immune response, but wh...

Sep 25, 2023

The nucleotide-binding oligomerization domain-like receptor protein 3 (NLRP3) inflammasome is an important part of the natural immune system that plays an important role in many diseases. Estrogen is ...

Sep 25, 2023

This study aimed to investigate alterations of outer retinal reflectivity on spectral-domain optical coherence tomography (OCT) in diabetic patients without clinically detectable retinopathy (NDR).In ...

Sep 25, 2023

Mechanisms responsible for the pathogenesis of diabetic retinal disease remain incompletely understood, but likely involve multiple cellular targets, including photoreceptors. Evidence suggests that d...

Sep 25, 2023

The glaucomas are a group of conditions leading to irreversible sight loss and characterised by progressive loss of retinal ganglion cells. Although not always elevated, intraocular pressure is the on...

Sep 25, 2023

In the present work, novel interpenetrated networks (IPNs) of [2-(methacryloyloxy)ethyl]dimethyl-(3-sulfopropyl)ammonium hydroxide) (SBMA) and poly(vinyl alcohol) (PVA) were prepared for the ocular co...

Sep 25, 2023

To assess the demographic characteristics and geographic distribution of neuro-ophthalmologists practicing in the US.A cross-sectional study.Neuro-ophthalmologists across the US.In this cross-sectiona...