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Ophthalmology General

Effect of Long-Term Topical Antiglaucoma Medication Use on the Ocular Surface.

Dec 10, 2020

The purpose of this study was to describe the prevalence and pattern of ocular surface disease (OSD) in glaucoma patients using preserved topical antiglaucoma medications in a Nigerian population.A co...

Efficacy and Safety of Sodium Hyaluronate/chondroitin Sulfate Preservative-free Ophthalmic Solution in the Treatment of Dry Eye: A Clinical Trial.

Dec 10, 2020

: To evaluate the efficacy of a preservative free sodium hyaluronate/chondroitin sulfate ophthalmic solution (SH/CS-PF) in patients with dry eye disease (DED). : This was a randomized phase IV, multic...

Ocular Discomfort and Quality of Life Among Patients in the Dry Eye Assessment and Management Study.

Dec 10, 2020

To assess the association of severity of ocular discomfort with measures of quality of life among patients with moderate to severe dry eye disease (DED).This is a prospective, observational, cohort st...

Machine Learning Based Automated Segmentation and Hybrid Feature Analysis for Diabetic Retinopathy Classification Using Fundus Image.

Dec 10, 2020

The object of this study was to demonstrate the ability of machine learning (ML) methods for the segmentation and classification of diabetic retinopathy (DR). Two-dimensional (2D) retinal fundus (RF) ...

Patient Perspectives of Diabetes and Diabetic Retinopathy Services in Kiribati: A Qualitative Study.

Dec 10, 2020

Diabetes mellitus is an increasing global health problem affecting millions of people worldwide, especially true in the Republic of Kiribati, with >20% of adults suffering from type 2 diabetes, and...

Robust and Interpretable Convolutional Neural Networks to Detect Glaucoma in Optical Coherence Tomography Images.

Dec 10, 2020

Recent studies suggest that deep learning systems can now achieve performance on par with medical experts in diagnosis of disease. A prime example is in the field of ophthalmology, where convolutional...

A wearable contact lens sensor for noninvasive in-situ monitoring of intraocular pressure.

Dec 10, 2020

Glaucoma is the second leading cause of blindness in the world. Intraocular pressure (IOP) is a primary indicator of glaucoma which can be measured for the treatment of the disease. This paper present...

Effect of Sensitivity Disparity Between the Two Eyes on Pointwise Monocular Sensitivity Under Binocular Viewing in Patients With Glaucoma.

Dec 10, 2020

PRéCIS:: A difference between monocular sensitivities measured with and without occlusion was observed in glaucoma. Monocular sensitivity without occlusion could have been affected differently by bin...

Choroidal alterations of Sturge-Weber syndrome secondary glaucoma and non-glaucoma port-wine stain patients distinguished by enhanced depth imaging optical coherence tomography.

Dec 10, 2020

To evaluate the choroidal changes in Sturge-Weber syndrome (SWS) secondary glaucoma and non-glaucoma port-wine stain (PWS) patients by enhanced depth imaging optical coherence tomography (EDI-OCT).SWS...

Calculating the economic burden of presumed microbial keratitis admissions at a tertiary referral centre in the UK.

Dec 10, 2020

Microbial keratitis (MK) is the most common non-surgical ophthalmic emergency admission in the UK. However, few prospective health-economic studies of MK have been performed, and no specific healthcar...

Microsporidial stromal keratitis: characterization of clinical features, and ultrastructural study by electron microscopy and efficacy of different surgical modalities

Dec 10, 2020

Researchers conducted this study to report the clinical manifestations, ultrastructure, and evaluate the efficacy of therapeutic lamellar keratectomy (TLK) and penetrating keratoplasty (PK) for micros...

Three-year follow-up of accelerated transepithelial corneal cross-linking for progressive paediatric keratoconus

Dec 08, 2020

Researchers did this study to investigate the long-term safety and efficacy of accelerated transepithelial corneal cross-linking (ATE-CXL) in children with progressive keratoconus. Fifty-three eyes o...

Long-term visual outcomes of the Boston type I keratoprosthesis in Canada

Dec 08, 2020

Researchers did this study to evaluate Boston type I keratoprosthesis (KPro) surgery’s long-term visual outcomes and identify risk factors for visual failure. The present study was a single surgeon...

Visual and refractive outcomes and complications in femtosecond laser-assisted versus conventional phacoemulsification cataract surgery: findings from a randomized, controlled clinical trial

Dec 08, 2020

Researchers conducted this study to compare visual and refractive outcomes, changes in IOP, and complications of FLACS to CPS in paired eyes from the same patients. This secondary analysis included 1...

Effectiveness of an innovative and comprehensive eye care model for individuals in residential care facilities: results of the residential ocular care (ROC) multicentred randomized controlled trial

Dec 08, 2020

The researchers did this study to assess the clinical and patient-centered effectiveness of a novel residential ocular care model in Australian individuals residing in residential care. The ROC arm c...

Normative patterns and factors associated with presbyopia progression in a multiethnic Asian population: the Singapore Epidemiology of Eye Diseases Study

Dec 08, 2020

Researchers conducted this research to investigate normative patterns and factors associated with presbyopia progression in a multiethnic Asian population. Malay, Indian and Chinese participants who ...

COG5 variants lead to complex early onset retinal degeneration, upregulation of PERK and DNA damage.

Dec 07, 2020

Leber congenital amaurosis (LCA), a form of autosomal recessive severe early-onset retinal degeneration, is an important cause of childhood blindness. This may be associated with systemic features or ...

Construction of a knowledge graph for diabetes complications from expert-reviewed clinical evidences.

Dec 07, 2020

A knowledge graph is a structured representation of data that can express entity and relational knowledge. More attention has been paid to the study of a clinical knowledge graph, especially in the fi...

Altered Expression of GJD2 Messenger RNA and the Coded Protein Connexin 36 in Negative Lens-induced Myopia of Guinea Pigs.

Dec 07, 2020

Decreased expression of the retinal GJD2 gene messenger RNA (mRNA) and connexin 36 (Cx36) protein in the guinea pig negative lens-induced myopia (LIM) model suggests their involvement in local retinal...

PROSPECTIVE CLINICAL EVALUATION OF THE EFFECTIVENESS OF ASYMMETRIC INTRACORNEAL RING WITH VARIABLE THICKNESS AND WIDTH FOR THE MANAGEMENT OF KERATOCONUS.

Dec 07, 2020

To evaluate the short-term clinical outcomes obtained with a new model of asymmetric intracorneal ring segments (ICRS) with variable thickness and base width in keratoconus.Four Spanish ophthalmologic...

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