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Ophthalmology General

Glaucoma is the Northern Ireland Cohort for the Longitudinal Study of Ageing (NICOLA)

Nov 26, 2020

This study was done to describe the cohort profile of the NICOLA and to report the prevalence, awareness, and associations with glaucoma. Using geographic stratification, a representative sample of n...

Determinants of corneal endothelial cell loss after sulcus placement of Ahmed and Baerveldt drainage device surgery

Nov 24, 2020

The study was done on patients who underwent multiple intraocular surgeries, we evaluated determinants of decreased CECD after sulcus placement following Ahmed and Baerveldt drainage device surgery. ...

Fifteen-year incidence rate and risk factors of pterygium in the Southern Indian state of Andhra Pradesh

Nov 24, 2020

The study was done to report 15-year incidence rate and associated risk factors of pterygium among people aged 30 years and above at baseline in the rural clusters of longitudinal APEDS III. 2290 par...

Intraocular pressure and circumpapillary retinal nerve fibre layer thickness in the Northern Ireland Cohort for the Longitudinal Study of Ageing (NICOLA)

Nov 24, 2020

This study was done to describe the distributions of and associations with intraocular pressure (IOP) and circumpapillary retinal nerve fibre layer (cRNFL) thickness in a population-based study. 3221...

Knowledge, attitudes and eye health-seeking behaviours in a population-based sample of people with diabetes in rural China

Nov 24, 2020

The study was done to assess knowledge of diabetes and acceptance of eye care among people with diabetes in rural China, to improve service uptake. Population-based study of people in Guangdong, Chin...

Parafoveal atrophy after human amniotic membrane graft for macular hole in patients with high myopia

Nov 24, 2020

The study was done to report the surgical outcome and postoperative hypopigmented change around fovea among patients with high myopia who received human amniotic membrane (hAM) graft transplantation f...

Retinal blood flow reduction in normal-tension glaucoma with single-hemifield damage by Doppler optical coherence tomography

Nov 24, 2020

The study was done to evaluate the associations between RBF and OCT structural measurements in NTG eyes with VF damage by the Doppler OCT. 43 consecutive eyes of 43 patients with NTG with VF defect c...

Long-term follow-up of cystinosis patients treated with 0.55% cysteamine hydrochloride

Nov 23, 2020

Cystinosis is a rare, autosomal recessive disorder causing defective transport of cystine out of lysosomes. Cystadrops (0.55% cysteamine hydrochloride in viscous solution) has been used on a named-pat...

A sialidosis type I cohort and a quantitative approach to multimodal ophthalmic imaging of the macular cherry-red spot

Nov 23, 2020

The study was done to describe the ophthalmologic findings on the largest cohort of patients with sialidosis type I due to deficiency of the lysosomal sialidase, NEU1 and to introduce a quantitative n...

Blindness short after treatment of acute primary angle closure in China

Nov 23, 2020

The study was done to explore the risk factors associated with blindness after treatment of APAC, and to identify the critical time window to decrease the rate of blindness. 1030 consecutive subjects...

Proposal and validation of a new grading system for pterygium (SLIT2)

Nov 23, 2020

The study was done to propose and validate a new pterygium grading system based on slit-lamp evaluation. 217 patients with pterygium were included. All patients underwent slit-lamp examination, and s...

The effect of posterior vitreous detachment on aflibercept response in diabetic macular oedema

Nov 23, 2020

The study was done to investigate the effect of posterior vitreous detachment (PVD) on aflibercept response in treatment-naïve diabetic macular oedema (DME). A retrospective cohort study.150 treatme...

Effects of congenital ptosis on the refractive development of eye and vision in children.

Nov 23, 2020

To investigate the influence of unilateral congenital ptosis on the development of the eye and vision in children.In this prospective observational study, 41 patients with unilateral congenital ptosis...

Myopia progression varies with age and severity of myopia.

Nov 23, 2020

To investigate annual myopia progression in individuals from South Indian states across different age groups, and its association with age of onset and severity of myopia.This retrospective study incl...

Consistency between optical coherence tomography and humphrey visual field for evaluating glaucomatous defects in high myopic eyes.

Nov 23, 2020

The study is to investigate the influence of high myopia on the consistency between optical coherence tomography (OCT) and visual field in primary open-angle glaucoma (POAG).We enrolled 37 patients wi...

A randomised clinical trial of multifocal contact lenses and contact lens discomfort.

Nov 23, 2020

To determine how multifocal contact lenses affect contact lens discomfort.This randomised, participant-masked, crossover clinical trial fitted 84 uncomfortable soft contact lens wearers (30-40 years ...

Esculetin protects human corneal epithelial cells from oxidative stress through Nrf-2 signaling pathway.

Nov 23, 2020

Dry eye formation often originates from oxidative damage to the ocular surface, which can be caused by external environment or internal pathologic factors. Esculetin (6, 7-dihydroxycoumarin) is a natu...

End of Study Results for the Ladder Phase 2 Trial of the Port Delivery System with Ranibizumab for Neovascular Age-Related Macular Degeneration.

Nov 23, 2020

To report the end of study results from the Ladder clinical trial of the Port Delivery System with ranibizumab (PDS) for the treatment of neovascular age-related macular degeneration (nAMD).Multicente...

Serum essential trace elements and toxic metals in Chinese diabetic retinopathy patients.

Nov 23, 2020

Trace elements are essential for the proper functioning of proteins, enzymes, and transcriptional factors. However, toxic metals will compete with essential trace elements, and damage enzymatic activi...

The SUSTech-SYSU dataset for automated exudate detection and diabetic retinopathy grading.

Nov 23, 2020

Automated detection of exudates from fundus images plays an important role in diabetic retinopathy (DR) screening and evaluation, for which supervised or semi-supervised learning methods are typically...

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