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Ophthalmology General

Gypenosides attenuate retinal degeneration in a zebrafish retinitis pigmentosa model.

Oct 15, 2020

Retinitis pigmentosa (RP) is a collection of heterogenous genetic retinal disorders resulting in cumulative retinal deterioration involving progressive loss of photoreceptors and eventually in total b...

Canaloplasty and Trabeculotomy with the OMNI System in Pseudophakic Patients with Open-Angle Glaucoma: the ROMEO Study.

Oct 15, 2020

Provide outcomes up to 12 months post-surgically for sequential canaloplasty and trabeculotomy with the OMNI surgical system (OMNI) in pseudophakic patients with mild to moderate open-angle glaucoma (...

Functional impact of a congenital stationary night blindness type 2 mutation depends on subunit composition of Ca1.4 Ca channels.

Oct 12, 2020

Voltage-gated Ca1 and Ca2 Ca channels are comprised of a pore-forming a1 subunit (Ca1.1-1.4, Ca2.1-2.3) and auxiliary β (β) and αδ (αδ-1-4) subunits. The properties of these channels vary with d...

Therapeutic potential of castor oil in managing blepharitis, meibomian gland dysfunction and dry eye.

Oct 12, 2020

The multifactorial pathogenesis and interrelationship of blepharitis, meibomian gland dysfunction and dry eye disease poses challenges to any therapeutic approach. Current treatments are mostly pallia...

Validation of a Novel Confocal Microscopy Imaging Protocol With Assessment of Reproducibility and Comparison of Nerve Metrics in Dry Eye Disease Compared With Controls.

Oct 12, 2020

The purposes of this study were to assess the reproducibility of a novel standardized technique for capturing corneal subbasal nerve plexus images with in vivo corneal confocal microscopy and to compa...

The cornea in keratoconjunctivitis sicca.

Oct 12, 2020

The lacrimal functional unit (LFU) regulates tear production, composition, distribution and clearance to maintain a stable protective tear layer that is essential for maintaining corneal epithelial he...

Lactoferrin Concentration in Human Tears and Ocular Diseases: A Meta-Analysis.

Oct 12, 2020

To evaluate the potential of lactoferrin (Lf) as a diagnostic biomarker for ocular diseases using a meta-analytic approach.All original studies reporting an estimate of the average Lf concentration in...

Optical coherence tomography angiography findings in patients undergoing transcorneal electrical stimulation for treating retinitis pigmentosa.

Oct 12, 2020

Transcorneal electrical stimulation (TES) is a novel treatment approach for patients with retinitis pigmentosa (RP). The aim of our study was to observe changes in optical coherence tomography angiogr...

Changes in intraocular pressure control in the first year after secondary intraocular lens implantation in children.

Oct 12, 2020

To compare intraocular pressure (IOP) control before and during the first year after secondary intraocular lens (IOL) implantation in children.This was a retrospective chart review of children who rec...

Limbal stem cell deficiency secondary to systemic paclitaxel (Taxol) for breast cancer: a case report.

Oct 12, 2020

Paclitaxel (PTX) is an antineoplastic drug widely used in treatments for ovarian, breast, and small-cell lung cancer. Although ocular effects associated with PTX have been previously described, very f...

Deep learning in glaucoma with optical coherence tomography: a review.

Oct 12, 2020

Deep learning (DL), a subset of artificial intelligence (AI) based on deep neural networks, has made significant breakthroughs in medical imaging, particularly for image classification and pattern rec...

Blood Biomarkers and 6- to 7-Year Childhood Outcomes Following Neonatal Encephalopathy.

Oct 12, 2020

 This study aimed to profile the cytokine/chemokine response from day 0 to 7 in infants (≥36 weeks of gestational age) with neonatal encephalopathy (NE) and to explore the association with long-te...

A Fairy Chemical Suppresses Retinal Angiogenesis as a HIF Inhibitor.

Oct 08, 2020

Neovascular retinal degeneration is a leading cause of blindness in advanced countries. Anti-vascular endothelial growth factor (VEGF) drugs have been used for neovascular retinal diseases; however, a...

Plastic Surgery and Cosmetic Procedures: Facial Injection Procedures.

Oct 08, 2020

Nonsurgical cosmetic procedures, including injection procedures, are among the fastest growing medical procedures. In 2018, botulinum toxin and hyaluronic acid injections were the two most common nons...

Moxifloxacin based axially swept wide-field fluorescence microscopy for high-speed imaging of conjunctival goblet cells.

Oct 08, 2020

Goblet cells (GCs) in the conjunctiva are specialized epithelial cells producing mucins on the ocular surface. GCs play important roles in maintaining homeostasis of the ocular surface, and GC dysfunc...

Profile of tear lipid mediator as a biomarker of inflammation for meibomian gland dysfunction and ocular surface diseases: Standard operating procedures.

Oct 08, 2020

Human tear is a biological fluid rich in lipids that is increasingly collected in clinical and biological research. The repertoire of small lipids or lipid mediators (often termed eicosanoids or oxyli...

An inadvertent issue of human retina exposure to endocrine disrupting chemicals: A safety assessment.

Oct 08, 2020

Endocrine disrupting chemicals (EDCs) are a group of chemical compounds that present a considerable public health problem due to their pervasiveness and associations with chronic diseases. EDCs can in...

An inhibitor of endothelial ETS transcription factors promotes physiologic and therapeutic vessel regression.

Oct 08, 2020

During the progression of ocular diseases such as retinopathy of prematurity and diabetic retinopathy, overgrowth of retinal blood vessels results in the formation of pathological neovascular tufts th...

A retrospective cohort study on the pathology and outcomes of type 2 diabetic patients with renal involvement.

Oct 08, 2020

To investigate the association of clinical and histological characteristics and the development of ESRD in T2DM patients with renal involvement.We conducted a retrospective analysis of clinical and pa...

Effectiveness of the Dexamethasone Implant in Lieu of Oral Corticosteroids in Intermediate and Posterior Uveitis Requiring Immunosuppression.

Oct 08, 2020

To evaluate dexamethasone intravitreal implant effectiveness in lieu of high-dose oral prednisone for short-term treatment of noninfectious intermediate and posterior uveitis in patients requiring imm...

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