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Ophthalmology General

Systemic alterations in leukocyte subsets and the protective role of NKT cells in the mouse model of diabetic retinopathy.

Sep 07, 2020

The involvement of leukocytes in the pathophysiology of DR has mostly examined the role of monocytes and neutrophils with little emphasis on other immune cell types. In this study, we determined the s...

Fufang Xueshuantong alleviates diabetic retinopathy by activating the PPAR signalling pathway and complement and coagulation cascades.

Sep 07, 2020

Fufang Xueshuantong (FXST) is a traditional Chinese patent medicine composed of Panax notoginseng (Burkill) F.H.Chen (Araliaceae), Salvia miltiorrhiza Bunge (Lamiaceae), Astragalus propinquus Schischk...

Lower Eyelid Horizontal Tightening in Prostaglandin Associated Periorbitopathy.

Sep 07, 2020

To determine the effect of chronic topical use of prostaglandin analogs for glaucoma on lower eyelid tension.A prospective case-control study was performed. Lower eyelid tension was measured in a grou...

An Evaluation Using Colored Doppler Ultrasonography of Central Retinal Artery Hemodynamics in the Healthy Eye in Individuals With Late Monocular Blindness.

Sep 07, 2020

Structural and functional changes occur in the brain after vision losses. The purpose of the present study was to investigate central retinal artery (CRA) hemodynamics in the healthy eye of individual...

Retinal changes in Alzheimer's disease- integrated prospects of imaging, functional and molecular advances.

Sep 07, 2020

Alzheimer's Disease (AD) is a devastating neurodegenerative disorder of the brain, clinically characterised by cognitive deficits that gradually worsen over time. There is, at present, no established ...

Using the West Midlands CONCERT to characterise regional incidence of acute-onset post cataract surgery endophthalmitis.

Sep 07, 2020

Whilst research and innovation is embedded within the UK's National Health Service (NHS) constitution, Doctors-in-training have little opportunity to contribute to designing, leading and recruiting in...

Cost-effectiveness of Autonomous Point-of-Care Diabetic Retinopathy Screening for Pediatric Patients With Diabetes.

Sep 07, 2020

Screening for diabetic retinopathy is recommended for children with type 1 diabetes (T1D) and type 2 diabetes (T2D), yet screening rates remain low. Point-of-care diabetic retinopathy screening using ...

Glaucoma and Intraocular Pressure

Sep 04, 2020

Intraocular pressure (IOP) refers to the fluid pressure inside the eye and is an essential aspect in the evaluation of patients at risk of glaucoma. But the prevalence of glaucoma associated with the ...

Application of graphene nanowalls in an intraocular pressure sensor.

Sep 03, 2020

As the second leading cause of blindness in the world, glaucoma is mainly caused by persistent high intraocular pressure (IOP) that compresses the optic nerve and causes permanent damage. Noninvasive ...

Diagnostic Markers in Ocular Sarcoidosis in A High TB Endemic Population - A Multicentre Study.

Sep 03, 2020

To look at markers to differentiate ocular sarcoidosis from ocular tuberculosis in a high TB endemic population.Retrospective multicenter study involving seven tertiary eyecare centers in India betwee...

Diabetes Induced Alterations in Murine Vitreous Proteome Are Mitigated by IL-6 Trans-Signaling Inhibition.

Sep 03, 2020

Diabetic retinopathy (DR) is a microvascular complication caused by prolonged hyperglycemia and characterized by leaky retinal vasculature and ischemia-induced angiogenesis. Vitreous humor is a gel-li...

Automatic Grading of Retinal Blood Vessel in Deep Retinal Image Diagnosis.

Sep 03, 2020

Automatic grading of retinal blood vessels from fundus image can be a useful tool for diagnosis, planning and treatment of eye. Automatic diagnosis of retinal images for early detection of glaucoma, s...

MiR-542-5p regulates the progression of diabetic retinopathy by targeting CARM1.

Sep 03, 2020

Diabetic retinopathy (DR), as the most frequent microvascular complication of diabetes mellitus (DM), causes vision loss and blindness in adults worldwide with increasing incidence. MicroRNAs (miRNAs)...

Research article miR-21-5p: A viable therapeutic strategy for regulating intraocular pressure.

Sep 03, 2020

Lowering intraocular pressure (IOP) is the most effective treatment of glaucoma, however most of the current available glaucoma drugs target a single molecule. MicroRNAs (miRNAs) are noncoding RNAs th...

Progression and Risk Factors of Nongeographic Atrophy

Sep 02, 2020

Nongeographic atrophy (NGA) refers to as the retinal pigment disturbances, including hyperpigmentation and hypopigmentation in CFPs. NGA can be caused in eyes treated with anti-vascular endothelial gr...

Gender Gap in Ophthalmology Conference Speakers

Sep 01, 2020

“Although the rates of women in medicine and ophthalmology are increasing, a gender gap still exists in senior positions, such as senior faculty, chairs of academic programs, and deans of medical sc...

Non-Physician Hospital CEO Cut after Participating in Surgery

Aug 31, 2020

Last week on Twitter I asked this question: The 130 (2.5%) of 5,213 respondents who said they would allow a CEO to make a skin incision highlight the unscientific nature of Twitter polls. Restr...

Prevalence and Risk Factors of Severe Dry Eye in Bangladesh-Based Factory Garment Workers.

Aug 31, 2020

This study sought to evaluate the prevalence of dry eye and meibomian gland dysfunction (MGD) and the associated factors of severe dry eye symptoms (SDES) among garments worker of Gazipur, Bangladesh....

Size of the associations between anticholinergic burden tool scores and adverse outcomes in older patients.

Aug 31, 2020

Background Several anticholinergic scales and equations to evaluate the anticholinergic burden have been previously created. Association of these instruments with the anticholinergic outcomes are usua...

Efficacy and tolerability of nortriptyline in the management of neuropathic corneal pain.

Aug 31, 2020

Neuropathic corneal pain (NCP) is a recently acknowledged disease entity. However, there is no consensus in potential treatment strategies, particularly in patients with a centralized component of pai...

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