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Ophthalmology General

Retinal Manifestations of Idiopathic Intracranial Hypertension.

Aug 31, 2020

Case series and systematic review to understand significant retinal changes in patients with idiopathic intracranial hypertension (IIH) using fundus photography and optical coherence tomography (OCT)....

Alpha-crystallin mutations alter lens metabolites in mouse models of human cataracts.

Aug 27, 2020

Cataracts are a major cause of blindness worldwide and commonly occur in individuals over 70 years old. Cataracts can also appear earlier in life due to genetic mutations. The lens proteins, αA- and ...

Reproduction Function in Male Patients with Bardet Biedl Syndrome.

Aug 27, 2020

Bardet-Biedl syndrome (BBS) is a ciliopathy with a wide spectrum of symptoms due to primary cilia dysfunction including genitourinary developmental anomalies as well as impaired reproduction particula...

Long non-coding RNA MEG3 promotes cataractogenesis by upregulating TP53INP1 expression in age-related cataract.

Aug 27, 2020

Age-related cataract (ARC) is the leading cause of visual impairment or even blindness among the aged population globally. Long non-coding RNA (LncRNA) has been proven to be the potential regulator of...

Do Head-Mounted Augmented Reality Devices Affect Muscle Activity and Eye Strain of Utility Workers Who Do Procedural Work? Studies of Operators and Manhole Workers.

Aug 27, 2020

The objective was to determine the effect of two head-mounted display (HMD) augmented reality (AR) devices on muscle activity and eye strain of electric utility workers. The AR devices were the Micros...

Study of Factors Influencing Dry Eye in Rheumatoid Arthritis.

Aug 27, 2020

The present study investigated the relationship between dry eye and the disease activity in patients with rheumatoid arthritis (RA).Patients with RA were divided by the Ocular Surface Disease Index (O...

Prevalence of symptomatic dry eye in breast cancer patients undergoing systemic adjuvant treatment: A cross-sectional study.

Aug 27, 2020

To investigate the prevalence of symptomatic dry eye (SDE) on women undergoing systemic adjuvant therapy for breast cancer and its association with treatment settings.Woman undergoing breast cancer sy...

A comparative evaluation of segmental analysis of macular layers in patients with early glaucoma, ocular hypertension, and healthy eyes.

Aug 27, 2020

To compare macular layer thicknesses between early glaucoma, ocular hypertension, and healthy eyes and to evaluate the accuracy of spectralis optical coherence tomography (OCT) segmentation software i...

Optogenetic Stimulation of Cholinergic Amacrine Cells Improves Capillary Blood Flow in Diabetic Retinopathy.

Aug 27, 2020

Disruption in blood supply to active retinal circuits is the earliest hallmark of diabetic retinopathy (DR) and has been primarily attributed to vascular deficiency. However, accumulating evidence sup...

Inflammatory cells proliferate in the choroid and retina without choroidal thickness change in early Type 1 diabetes.

Aug 27, 2020

Increasing evidence points to inflammation as a key factor in the pathogenesis of diabetic retinopathy (DR). Choroidal inflammatory changes in diabetes have been reported and in vivo choroidal thickne...

Cost-Related Medication Non-Adherence in a Nationally Representative U.S. Population with Self-Reported Glaucoma.

Aug 27, 2020

To determine the rates of cost-related non-adherence to medications among U.S. adults with glaucoma and to determine if participants with glaucoma have more cost-related medication non-adherence than ...

iStent inject®: A Comprehensive Survey of the Literature.

Aug 27, 2020

Micro-incisional glaucoma surgeries (MIGS) are novel surgical procedures for treatment of glaucoma. They aim to safely and effectively reduce intraocular pressure (IOP) with minimal trauma to the eye ...

Artificial Iris Exchange.

Aug 27, 2020

To describe the indications, motivations, and outcomes of artificial iris exchange.Stein Eye Institute.Consecutive case series.Review of medical records of patients implanted with an artificial iris d...

Plasma fibroblast skin tightening treatment resulting in bilateral chemical eye injury secondary to EMLA cream: a case report.

Aug 27, 2020

Plasma fibroblast skin tightening treatment is a relatively novel and growing minimally invasive aesthetic skin procedure. The treatment claims to rejuvenate skin by improving facial lines, wrinkles a...

In Vitro Effect of Pitavastatin and Its Synergistic Activity with Isavuconazole against .

Aug 24, 2020

keratitis (AK) can occur in healthy individuals wearing contact lenses and it is a painful, blinding infection of the cornea caused by a free-living ameba . Current treatment for AK relies on a combi...

Oxidative Stress Markers and the Retinopathy of Prematurity.

Aug 24, 2020

Retinopathy of prematurity (ROP) is a leading cause of potentially preventable blindness in low birth weight preterm infants. Several perinatal and postnatal factors contribute to the incomplete matur...

Risks and Benefits of Surgical Excision of Orbital Cavernous Venous Malformations (So-Called Cavernous Hemangioma): Factors Influencing the Outcome.

Aug 24, 2020

To assess risks and benefits associated with surgical excision of orbital cavernous venous malformation and analyze factors influencing the outcome.Design: cohort study.164 consecutive patients underg...

Novel Approaches for Imaging-Based Diagnosis of Ocular Surface Disease.

Aug 24, 2020

Imaging has become indispensable in the diagnosis and management of diseases in the posterior part of the eye. In recent years, imaging techniques for the anterior segment are also gaining importance ...

Nivolumab-Induced Ulcerative Keratitis-A Case Report.

Aug 24, 2020

To describe a case of nivolumab-induced ulcerative keratitis rapidly recovering on topical steroid treatment and to determine changes in cytokine levels in the tear fluid caused by nivolumab.We report...

Safety of KPI-121 Ophthalmic Suspension 0.25% in Patients With Dry Eye Disease: A Pooled Analysis of 4 Multicenter, Randomized, Vehicle-Controlled Studies.

Aug 24, 2020

The safety of KPI-121 0.25%, an ophthalmic nanoparticle suspension of loteprednol etabonate, was evaluated in subjects with dry eye disease (DED) in one phase 2 and three phase 3 randomized trials of ...

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