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Ophthalmology General

Prospective Interventional Cohort Study of Ocular Surface Disease Changes in Eyes After Trabecular Micro-Bypass Stent(s) Implantation (iStent or iStent inject) with Phacoemulsification.

Aug 17, 2020

This study sought to assess ocular surface disease changes following cataract surgery combined with trabecular micro-bypass stent(s) implantation (iStent or iStent inject).This prospective interventio...

Effect of acupuncture versus artificial tears for dry eye disease: A protocol for systematic review and meta-analysis.

Aug 17, 2020

The global prevalence of dry eye disease (DED) ranged from 5% to 50%, accompanied by the yearly increasing trend and younger onset. To date artificial tear serves as a mainstay therapy for DED managem...

Diabetic retinopathy among Omanis: Prevalence and clinical profile.

Aug 17, 2020

The aim of this study is to describe the prevalence, severity and clinical profile of diabetic retinopathy (DR) among Omani diabetic patients attending a tertiary care hospital.This is a retrospective...

THEIA™ development, and testing of artificial intelligence-based primary triage of diabetic retinopathy screening images in New Zealand.

Aug 17, 2020

To develop and evaluate an artificial intelligence triage system with high sensitivity for detecting referable diabetic retinopathy and maculopathy, while maintaining high specificity for non-referabl...

Ocular Hypertension Drives Remodeling of AMPA Receptors in Select Populations of Retinal Ganglion Cells.

Aug 17, 2020

AMPA-type glutamate receptors in the CNS are normally impermeable to Ca, but the aberrant expression of Ca-permeable AMPA receptors (CP-AMPARs) occurs in pathological conditions such as ischemia or ep...

Is the Xen® Gel Stent really minimally invasive?

Aug 17, 2020

To describe a case of severe endophthalmitis in a patient with a cystic, avascular filtering bleb who had been implanted with a Xen® Gel Stent 21 months previously.A 64-year-old woman with open-angl...

Assessment of angle closure spectrum disease as a continuum of change using gonioscopy and anterior segment optical coherence tomography.

Aug 17, 2020

Studies examining the anterior chamber angle and angle closure disease often compare quantitative angle information obtained using anterior segment optical coherence tomography (ASOCT) with one of sev...

Ten-year review of a shared care approach in the management of ocular chlamydia trachomatis infections.

Aug 17, 2020

Since 2007, the ocular 4:1 multiplex PCR assay in NHS Greater Glasgow and Clyde includes Chlamydia trachomatis (ocular chlamydia (OC)) testing. OC can be identified following routine 'viral' ophthalmi...

Chronic Conditions, Visual Impairment, & Healthcare Use: Examining Key Patterns

Aug 13, 2020

The number of older adults in the United States living with multimorbidity—defined as the co-occurrence of at least 2 chronic conditions—has increased rapidly over the past few decades. “Visual ...

[Medical Management of Glaucoma].

Aug 13, 2020

Glaucoma is the leading cause of irreversible blindness in Germany and in the world. Due to the multifactorial genesis of the disease, there are multiple therapeutic approaches for preventing its prog...

[Preservative-free fixed combination in the treatment of open-angle glaucoma and ocular hypertension: the VISIONARY Study (EUPAS22204)].

Aug 13, 2020

Preservative-free fixed combination of 0.0015% Tafluprost and 0.5% Timolol (PF tafluprost/timolol FC) has demonstrated good antihypertensive effect and patient tolerance in randomized controlled clini...

Arginase 1 is involved in lacrimal hyposecretion in male NOD mice, a model of Sjögren's syndrome, regardless of dacryoadenitis status.

Aug 13, 2020

Few reports have explored the possibility of involvement of non-inflammatory factors in lacrimal hyposecretion in Sjögren's syndrome (SS). RNA-seq analysis revealed that only 4 genes, including argin...

Controlled differential evolution based detection of neovascularization on optic disc using support vector machine.

Aug 13, 2020

The severe stage of Diabetic Retinopathy (DR) is characterized by the growth of new blood vessels which is called Neovascularization (NV). The abnormally grown blood vessels on the disc are breakable ...

Of neurons and pericytes: The neuro-vascular approach to diabetic retinopathy.

Aug 13, 2020

Diabetic retinopathy (DR) is a frequent complication of diabetes mellitus and an increasingly common cause of visual impairment. Blood vessel damage occurs as the disease progresses, leading to ischem...

Level of hormones in menopause in relation to diabetic retinopathy among type 2 diabetic women.

Aug 13, 2020

Hormonal transition among middle-aged women with type 2 diabetes may exert an impact in the development of diabetic retinopathy (DR). In this cross-sectional study, we aimed to assess the levels of es...

[Diagnosis and prediction of the course of primary open-angle glaucoma by the level of local cytokines].

Aug 13, 2020

Glaucoma is the leading cause of irreversible blindness in all countries and is expected to increase in patients with this pathology in the coming years. Currently, the development of the disease is a...

Sociodemographic Factors Influencing Rhegmatogenous Retinal Detachment Presentation and Outcome.

Aug 13, 2020

The impact of sociodemographic factors on the presentation and outcomes of rhegmatogenous retinal detachment (RRD) in the United States have not been described. We analyzed the impact of these factors...

Impact of the Support, Educate, Empower (SEE) personalized glaucoma coaching program pilot study on eye drop instillation technique and self-efficacy.

Aug 13, 2020

To assess the Support, Educate, Empower (SEE) personalized glaucoma coaching program impact on 1) eye drop instillation technique and 2) eye drop instillation self-efficacy.A prospective pre-post pilo...

DICER1 in the Pathogenesis of Age-related Macular Degeneration (AMD) - RNA Accumulation versus miRNA Dysregulation.

Aug 10, 2020

DICER1 deficiency in the retinal pigment epithelium (RPE) was associated with the accumulation of transcripts and implicated in geographic atrophy (GA), a form of age-related macular degeneration (AM...

Automated identification of retinopathy of prematurity by image-based deep learning.

Aug 10, 2020

Retinopathy of prematurity (ROP) is a leading cause of childhood blindness worldwide but can be a treatable retinal disease with appropriate and timely diagnosis. This study was performed to develop a...

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