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Ophthalmology General

Isoliquiritigenin downregulates miR-195 and attenuates oxidative stress and inflammation in STZ-induced retinal injury.

Jul 27, 2020

Diabetic retinopathy (DR) is a major microvascular complication of diabetes mellitus that leads to significant vision loss. Isoliquiritigenin (ISL) is a bioactive flavonoid found in the root of licori...

Evaluation of retinal neurovascular structures by optical coherence tomography and optical coherence tomography angiography in children and adolescents with type 1 diabetes mellitus without clinical sign of diabetic retinopathy.

Jul 27, 2020

The aim of the study was to investigate whether retinal neurovascular structural impairment in children and adolescents with type 1 diabetes mellitus (T1D) without clinical signs of diabetic retinopat...

Differences in outflow channels between two eyes of unilateral primary congenital glaucoma.

Jul 27, 2020

Primary congenital glaucoma (PCG) occurs in only one eye in some patients. We aimed to characterize anatomical features of the angle and Schlemm's canal (SC) in vivo among fellow eyes of patients with...

Predictive factors of Boston Type I Keratoprosthesis outcomes: A long-term analysis.

Jul 27, 2020

To study the long-term visual- and device retention-related outcomes and complications of the Boston Type I Keratoprosthesis (KPro).Single-center, retrospective cohort study of all patients undergoing...

Primary endoscopic management of apoplexy in a giant pituitary adenoma.

Jul 27, 2020

Sellar lesions with large suprasellar extension represent a neurosurgical challenge because of their nature and anatomical complexity. The goal of the extended transphenoidal-transtuberculum approach ...

Ophthalmic Technology Assessment - Sentinel Lymph Node Biopsy for Eyelid and Conjunctival Malignancy: A report by the American Academy of Ophthalmology.

Jul 27, 2020

To determine the efficacy and safety of sentinel lymph node biopsy (SLNB) in the management of eyelid and conjunctival malignancy.A literature search was performed in August 2019 and January 2020 for ...

Epigenetic hallmarks of age-related macular degeneration are recapitulated in a photosensitive mouse model.

Jul 23, 2020

Age-related macular degeneration (AMD) is a chronic, multifactorial disorder and a leading cause of blindness in the elderly. Characterized by progressive photoreceptor degeneration in the central ret...

Resilience, anxiety and depression, coping style, social support and their correlation in parents of premature infants undergoing outpatient fundus examination for retinopathy of prematurity.

Jul 23, 2020

Retinopathy of prematurity (ROP) has become the main cause of blindness in children. To study resilience, anxiety and depression, coping style and social support and their correlation in parents of pr...

Retinal Glial and Choroidal Vascular Pathology in Donors Clinically Diagnosed With Stargardt Disease.

Jul 23, 2020

The present study investigated retinal glia and choroidal vessels in flatmounts and sections from individuals with clinically diagnosed Stargardt disease (STGD).Eyes from three donors clinically diagn...

Effect of natural extract eye drops in dry eye disease rats.

Jul 23, 2020

To investigate the therapeutic effect of natural extract eye drops containing bee venom, musk, and deer antlers in dry eye disease (DED) animal models.Scopolamine-injected DED rats and lacrimal gland-...

Metabolomic analysis in ophthalmology.

Jul 23, 2020

Modern science takes into account phenotype complexity and establishes approaches to track changes on every possible level. Many "omics" studies have been developed over the last decade. Metabolomic a...

Ocular Demodex: a systematic review of the clinical literature.

Jul 23, 2020

There is increasing clinical and research interest in the potential contribution of Demodex to ocular surface disease. The aim of this systematic review was to summarise and synthesise current clinica...

Zinc oxide nanoparticles from Cyperus rotundus attenuates diabetic retinopathy by inhibiting NLRP3 inflammasome activation in STZ-induced diabetic rats.

Jul 23, 2020

Diabetic retinopathy (DRP) is a retinal disease caused by diabetes mellitus, which is categorized by microvascular lesions present in the retina such as vascular leakage, vascular proliferation, and r...

Unique molecular signatures of microRNAs in ocular fluids and plasma in diabetic retinopathy.

Jul 23, 2020

The main objective of this pilot study was to identify circulatory microRNAs in aqueous or plasma that were reflecting changes in vitreous of diabetic retinopathy patients. Aqueous, vitreous and plasm...

Retinal proteomics of experimental glaucoma model reveal intraocular pressure-induced mediators of neurodegenerative changes.

Jul 23, 2020

Current evidence suggests that exposure to chronically induced intraocular pressure (IOP) leads to neurodegenerative changes in the inner retina. This study aimed to determine retinal proteomic altera...

Comparison of peripapillary Capillary Density in Glaucoma Patients of African and European descent.

Jul 23, 2020

To evaluate racial differences in optic nerve head peripapillary capillary density measured by optical coherence tomography angiography (OCTA) in patients with open-angle glaucoma.Observational, cross...

Glaucoma after ocular surgery or trauma: the role of infiltrating monocytes and their response to cytokine inhibitors.

Jul 23, 2020

Glaucoma is a frequent and devastating long-term complication following ocular trauma, including corneal surgery, open globe injury, chemical burn, infection, etc. Post-event inflammation and neurogli...

Filtering-associated Endophthalmitis Following Trabeculectomy or Tube-shunt Implant.

Jul 23, 2020

To determine the rate, clinical features, and outcomes of filtering-associated endophthalmitis in eyes that underwent trabeculectomy or tube-shunt implantation.Retrospective database study with select...

Return to the Operating Room after Vitrectomy for Vitreous Opacities: IRIS® Registry Analysis.

Jul 23, 2020

To investigate the rate of return to the operating room after vitrectomy surgery for vitreous opacities DESIGN: A retrospective registry cohort PARTICIPANTS: Individuals receiving care in ophthalmolog...

Stakeholder-Engaged Derivation of Patient-Informed Value Elements.

Jul 20, 2020

Our objective was to identify patient-informed value elements that can be used to make value assessment more patient centered.Mixed methods were used iteratively to collect and integrate qualitative a...

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