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Ophthalmology General

Autologous serum eye drops improve tear production, both lachrymal flow and stability tests and conjunctival impression cytology with transfer in dry eye disease.

Jun 15, 2020

Autologous serum eye drops, produced by separation of liquid and cellular components of the patient's blood, contain biological nutrients present in natural tears. The aim of this study was to analyse...

The effect of astaxanthin on inflammation in hyperosmolarity of experimental dry eye model in vitro and in vivo.

Jun 15, 2020

Hyperosmolarity is pro-inflammatory stress to the ocular surface epithelium for dry eye disease (DED). Astaxanthin (AST) is a kind of carotene, which exists in seafood and has been proved to inhibit i...

Blepharospasm, dry eye and extractable nuclear antigen antibodies.

Jun 15, 2020

To study whether there is an association between benign essential blepharospasm and Sjögren's syndrome by analyzing the presence of antibodies to extractable nuclear antigens in this population.Seven...

Destruction of the blood-retina barrier in diabetic retinopathy depends on angiotensin-converting enzyme-mediated TGF-β1/Smad signaling pathway activation.

Jun 15, 2020

Diabetes mellitus (DM) is a systemic, chronic metabolic disease that is related to heredity and autoimmunity and is often accompanied by complications of retinopathy. However, the causative mechanism ...

Artificial intelligence for anterior segment diseases: Emerging applications in ophthalmology.

Jun 15, 2020

With the advancement of computational power, refinement of learning algorithms and architectures, and availability of big data, artificial intelligence (AI) technology, particularly with machine learn...

Omidenepag Isopropyl Versus Latanoprost in Primary Open-angle Glaucoma and Ocular Hypertension: ThePhase 3 AYAME Study.

Jun 15, 2020

To evaluate the efficacy and safety of omidenepag isopropyl (OMDI), a selective, non-prostaglandin, prostanoid EP2 receptor agonist, in Japanese patients with primary open-angle glaucoma (POAG) or ocu...

Differential adaptations in rod outer segment disc membranes in different models of congenital stationary night blindness.

Jun 15, 2020

Rod photoreceptor cells initiate scotopic vision when the light receptor rhodopsin absorbs a photon of light to initiate phototransduction. These photoreceptor cells are exquisitely sensitive and have...

MicroRNA miR-29c-3p modulates FOS expression to repress EMT and cell proliferation while induces apoptosis in TGF-β2-treated lens epithelial cells regulated by lncRNA KCNQ1OT1.

Jun 15, 2020

Age-related cataract (ARC) is a main cause of blindness for elderly people. MicroRNA hsa_miR-29c-3p (miR-29c-3p) was implicated in many biological processes in complicated diseases. However, the biolo...

Association of Weight-Adjusted Caffeine and β-Blocker Use With Ophthalmology Fellow Performance During Simulated Vitreoretinal Microsurgery.

Jun 15, 2020

Vitreoretinal surgery can be technically challenging and is limited by physiologic characteristics of the surgeon. Factors that improve accuracy and precision of the vitreoretinal surgeon are invaluab...

Biochemical basis for the regulation of biosynthesis of antiparasitics by bacterial hormones.

Jun 11, 2020

Diffusible small molecule microbial hormones drastically alter the expression profiles of antibiotics and other drugs in actinobacteria. For example, avenolide (a butenolide) regulates production of a...

The effect of oral isotretinoin therapy on meibomian gland morphology and dry eye tests.

Jun 11, 2020

The aim of study was to evaluate the effects of oral isotretinoin on meibomian gland (MG) morphology detected with non-contact meibography and to investigate its relation with clinical dry eye tests....

Fibromyalgia Syndrome and Eye - a review.

Jun 11, 2020

Fibromyalgia is a chronic, widespread pain syndrome, with unclear etiology, characterized by fatigue, sleeping problems, cognitive disorders, somatic complaints and severe pain in tender points of the...

Cataract surgery and dry eye disease: A review.

Jun 11, 2020

To review published literature concerning cataract surgery and dry eye disease (DED).A search was undertaken using the following: PubMed (all years), Web of Science (all years), Ovid MEDLINE(R) (1946 ...

The relationship of central corneal thickness with the status of diabetic retinopathy.

Jun 11, 2020

To compare central corneal thickness (CCT) values measured by three different devices: slit-scanning topography (SST), ultrasonic pachymetry (UP), and optical coherence tomography (OCT) in diabetic ey...

Personalising screening of sight-threatening diabetic retinopathy - qualitative evidence to inform effective implementation.

Jun 11, 2020

Internationally, systematic screening for sight-threatening diabetic retinopathy (STDR) usually includes annual recall. Researchers and policy-makers support extending screening intervals, citing evid...

Morphological changes in intraretinal microvascular abnormalities after anti-VEGF therapy visualized on optical coherence tomography angiography.

Jun 11, 2020

To examine the baseline morphological characteristics and alterations in intraretinal microvascular abnormalities (IRMAs) in response to anti-vascular endothelial growth factor (anti-VEGF) treatment, ...

Surgical clipping of ophthalmic artery aneurysms: a single center series.

Jun 11, 2020

The purpose of this study was to summary the characteristics of ophthalmic artery (OphA) aneurysms and to obtain the independent risk factors for poor prognosis of microsurgical clipping treatment fo...

Effectiveness of Blepharoptosis Surgery in Patients With Deepening of the Upper Eyelid Sulcus.

Jun 11, 2020

The purpose of this retrospective study was to evaluate the effectiveness of blepharoptosis surgery in patients with deepening of the upper eyelid sulcus (DUES). This case series included 10 consecuti...

Intraocular Lens Implantation in the Absence of Zonular Support: An Outcomes and Safety Update: A Report by the American Academy of Ophthalmology.

Jun 11, 2020

To review the published literature on the visual acuity results and complications of different surgical techniques for intraocular lens (IOL) implantation in the absence of zonular support.Peer-review...

Cerebellar Parieto-occipital Posterior Reversible Encephalopathy Syndrome and Cerebral Metamorphopsia Associated with Asymptomatic Atrial Septum Vegetation and Renal Disease: Case Report.

Jun 11, 2020

BACKGROUND Posterior reversible encephalopathy syndrome (PRES) is a poorly characterized and enigmatic syndrome. Despite consistently presenting with nervous system vasogenic edema, this malady has be...

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