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Ophthalmology General

Personalising screening of sight-threatening diabetic retinopathy - qualitative evidence to inform effective implementation.

Jun 11, 2020

Internationally, systematic screening for sight-threatening diabetic retinopathy (STDR) usually includes annual recall. Researchers and policy-makers support extending screening intervals, citing evid...

Morphological changes in intraretinal microvascular abnormalities after anti-VEGF therapy visualized on optical coherence tomography angiography.

Jun 11, 2020

To examine the baseline morphological characteristics and alterations in intraretinal microvascular abnormalities (IRMAs) in response to anti-vascular endothelial growth factor (anti-VEGF) treatment, ...

Surgical clipping of ophthalmic artery aneurysms: a single center series.

Jun 11, 2020

The purpose of this study was to summary the characteristics of ophthalmic artery (OphA) aneurysms and to obtain the independent risk factors for poor prognosis of microsurgical clipping treatment fo...

Effectiveness of Blepharoptosis Surgery in Patients With Deepening of the Upper Eyelid Sulcus.

Jun 11, 2020

The purpose of this retrospective study was to evaluate the effectiveness of blepharoptosis surgery in patients with deepening of the upper eyelid sulcus (DUES). This case series included 10 consecuti...

Intraocular Lens Implantation in the Absence of Zonular Support: An Outcomes and Safety Update: A Report by the American Academy of Ophthalmology.

Jun 11, 2020

To review the published literature on the visual acuity results and complications of different surgical techniques for intraocular lens (IOL) implantation in the absence of zonular support.Peer-review...

Cerebellar Parieto-occipital Posterior Reversible Encephalopathy Syndrome and Cerebral Metamorphopsia Associated with Asymptomatic Atrial Septum Vegetation and Renal Disease: Case Report.

Jun 11, 2020

BACKGROUND Posterior reversible encephalopathy syndrome (PRES) is a poorly characterized and enigmatic syndrome. Despite consistently presenting with nervous system vasogenic edema, this malady has be...

Subspecialty Differences in Managing Pediatric Cataracts Associated With Uveitis

Jun 08, 2020

Pediatric uveitis is a potentially serious condition that can increase risks for severe ocular complications leading to permanent vision loss. “Visually significant cataracts occur in more than 70% ...

Nanoparticulate Drug Delivery to the Retina.

Jun 08, 2020

Retinal diseases, such as age-related macular degeneration and diabetic retinopathy, are the leading causes of blindness worldwide. The mainstay of treatment for these blinding diseases remains to be ...

Corneal Blindness in Asia: A Systematic Review and Meta-Analysis to Identify Challenges and Opportunities.

Jun 08, 2020

To describe the causes and prevalence of moderate-to-severe visual impairment (MSVI) and blindness from corneal diseases, as well as corneal transplantation across Asia.A meta-analysis of the publishe...

Trends in the Utilization of Sodium Hyaluronate Eye Drops, Including Disposable and Multiuse Forms, in South Korea: A 14-Year Longitudinal Retrospective Cohort Study.

Jun 08, 2020

Sodium hyaluronate eye drops are frequently prescribed for dry eye disease in South Korea.This study analyzed the trends in the utilization of sodium hyaluronate eye drops and evaluate the impact of t...

Efficacy of topical bevacizumab 0.05% eye drops in dry eye disease: A double-masked, randomized trial.

Jun 08, 2020

The objective of this double-masked, placebo-controlled, randomized trial was to assess the efficacy and safety of bevacizumab 0.05% eye drops in dry eye patients. This study included Dry Eye Workshop...

Correlation of corneal immune cell changes with clinical severity in dry eye disease: An in vivo confocal microscopy study.

Jun 08, 2020

To evaluate corneal immune dendritiform cell (DC) changes in dry eye disease (DED) using in vivo confocal microscopy (IVCM) and to correlate IVCM parameters with clinical severity.This was a retrospec...

[Effect of acute insulin therapy on the concentration of vascular endothelial growth factor A (VEGF-A) in the intraocular fluid in an experiment].

Jun 08, 2020

To study the effect of insulin therapy on the concentration of vascular endothelial growth factor A (VEGF-A) in the intraocular fluid of rats with alloxan model of diabetes mellitus.The experiment was...

Performance of deep neural network-based artificial intelligence method in diabetic retinopathy screening: a systematic review and meta-analysis of diagnostic test accuracy.

Jun 08, 2020

Automatic diabetic retinopathy screening system based on neural networks has been used to detect diabetic retinopathy (DR). However, there is no quantitative synthesis of performance of these methods....

[Prevalence of ophthalmic diseases in the population older than 50 years].

Jun 08, 2020

The ageing of population is accompanied by an increase in the frequency of chronic diseases, including ophthalmic. The progression of ophthalmologic disturbances has population specificity and its ana...

Fréchet PDF based Matched Filter Approach for Retinal Blood Vessels Segmentation.

Jun 08, 2020

Retinal pathology diseases such as glaucoma, obesity, diabetes, hypertension etc. have deadliest impact on life of human being today. Retinal blood vessels consist of various significant information w...

A Safe Doppler Ultrasound-Guided Method for Nasolabial Fold Correction With Hyaluronic Acid Filler.

Jun 08, 2020

Injection of hyaluronic acid filler is a common procedure for nasolabial fold correction. However, it poses a risk of vascular compromise, which can result in skin necrosis and blindness.We aimed to e...

Hypomethylation of Notch1 DNA is Associated with the Occurrence of Uveitis.

Jun 04, 2020

Uveitis is a serious intraocular inflammatory disease that can lead to visual impairment even blindness worldwide. Notch signaling can regulate the differentiation of naïve CD4 T cells, influencing t...

Determination of Tear Lipid Film Thickness Based on a Reflected Placido Disk Tear Film Analyzer.

Jun 04, 2020

This study aims at determining the thickness of the tear lipid layer (LL) observed from a placido-disc-based tear film analyzer. We prospectively collected reflections of placido-disk LL images using ...

Ocular Disease Therapeutics: Design and Delivery of Drugs for Diseases of the Eye.

Jun 04, 2020

The ocular drug discovery field has evidenced significant advancement in the past decade. The FDA approvals of Rhopressa, Vyzulta, and Roclatan for glaucoma, Brolucizumab for wet age-related macular d...

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