May 26, 2020

To analyze the pathophysiological differences between patients with dry eye disease (DED) having different tear film break-up patterns (TBUPs).This investigative analysis involved 91 eyes of 91 patien...

May 26, 2020

Oxidative stress is widely known to be a major contributor in the pathogenesis of dry eye disease (DED). 4-Hydroxynonenal (4-HNE), a well-known byproduct frequently measured as an indicator of oxidati...

May 26, 2020

The lacrimal glands produce the aqueous component of the pre-ocular tear film, which is essential for ocular health and optimal vision. This review explores its history, current understanding and rece...

May 26, 2020

The majority of blinding conditions arise due to chronic pathologies in the retina. During the last two decades, antibody-based medicines administered by intravitreal injection directly into the back ...

May 26, 2020

To determine whether a quantitative approach to assessment of the severity of diabetic retinopathy (DR) lesions on ultrawide field (UWF) images can provide new parameters to predict progression to pro...

May 26, 2020

Retinal vascular caliber has been linked to diabetic retinopathy (DR). Newer imaging technologies allow analysis of retinal vascular caliber beyond the standard areas surrounding the optic disc. We in...

May 26, 2020

We examined the longitudinal association of baseline alcohol intake and frequency with the 6-year incidence and progression of diabetic retinopathy (DR) in a population-based cohort of Singaporean Ind...

May 26, 2020

Long non-coding RNA (lncRNA) VIM Antisense RNA 1 (VIM-AS1) has been reported to be correlated with type 2 diabetes (T2D) susceptibility, while the roles of this lncRNA in T2D and its complications rem...

May 26, 2020

Prevalence of visual impairment (VI) and access to services can vary significantly across and between different population groups. With renewed focus on universal health coverage and leaving no one be...

May 26, 2020

To evaluate the effect of a mobile-based screening programme on eye care utilization in Iran.In this cluster randomized community trial, a representative sample of residents aged≥50 years from urba...

May 26, 2020

To investigate rates of structural and functional change in a large clinical population of glaucoma and glaucoma suspect patients.Retrospective cohort.29,548 spectral-domain optical coherence tomograp...

May 26, 2020

Trabeculectomy has been performed since the mid-1960s and remains the gold standard for glaucoma surgery. Newer surgical options have evolved, collectively referred to as minimally invasive glaucoma s...

May 26, 2020

BACKGROUND Keratitis is a complex condition in humans and is the second most common cause of legal blindness worldwide. MATERIAL AND METHODS To reveal the genomic loci underlying keratitis, we perform...

May 26, 2020

Paediatric Horner's syndrome (HS) may present atypically with incomplete or intermittent clinical features, yet could represent sinister pathology including neuroblastoma. We aim to report the frequen...

May 26, 2020

Four free-ranging peregrine falcons (Falco peregrinus) were submitted with a history of unilateral or bilateral blindness and central nervous signs to a veterinary clinic in Germany. There were no ind...

May 12, 2020

To assess the clinical safety and efficacy of adjunctive therapy using Vizoovet to ameliorate clinical signs of keratoconjunctivitis sicca (KCS) in dogs.Twenty client-owned dogs.Canine patients diagno...

May 12, 2020

In this study, we quantify Pigment Epithelium-derived Factor (PEDF) secreted by corneal epithelial cells and its immunomodulatory functions in a murine model of dry eye disease (DED).We induced DED in...

May 12, 2020

To assess symptoms and signs of the dry anophthalmic socket syndrome (DASS) in a standardized manner.87 unilateral anophthalmic patients were evaluated using the Ocular Surface Disease Index (OSDI), t...

May 12, 2020

To evaluate corneal parameters of rheumatoid arthritis (RA) patients by corneal topography.One hundred two RA patients and 60 control subjects were enrolled. Corneal topography measurements and ophtha...

May 12, 2020

Dry eye disease (DED) is a common ocular condition that can impair vision and may adversely impact quality of life. Due to the inflammatory nature of this disorder, topical corticosteroids are an effe...