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Ophthalmology General

Is it Usher syndrome? Collaborative diagnosis and molecular genetics of patients with visual impairment and hearing loss.

Apr 14, 2020

: Usher syndrome is the most common hereditary syndrome combining deafness and blindness. In the 2017 National Child Count of Children and Youth who are Deaf-Blind, Usher syndrome represented 329 of 1...

Evaluation of the association between five genetic variants and primary open-angle glaucoma in a Han Chinese population.

Apr 14, 2020

: A large genome-wide association study showed that five new variants, { (rs3816415), (rs1258267), (rs736893), (rs7494379), and (rs3739821)}, were associated primary angle-closure glaucoma (PACG)....

Association of High-Mobility Group Box-1 with Inflammation-Related Cytokines in the Aqueous Humor with Acute Primary Angle-Closure eyes.

Apr 14, 2020

Aiming at measuring levels of High-mobility group box-1 (HMGB1) and inflammation-related cytokines in the aqueous humor of patients with acute primary angle-closure glaucoma (APAG) and age-related cat...

Ginkgo Biloba Extract in Ophthalmic and Systemic Disease, With a Focus on Normal-Tension Glaucoma.

Apr 14, 2020

Glaucoma is a neurodegenerative eye disease that results in retinal ganglion cell loss and ultimately loss of vision. Elevated intraocular pressure (IOP) is the most common known risk factor for retin...

Comparison of Rate of change between Bruch's Membrane Opening-Minimum Rim Width and RNFL in Eyes showing Optic Disc Hemorrhage.

Apr 14, 2020

To investigate and compare the longitudinal rate of change of Bruch's membrane opening-minimum rim width(BMO-MRW) and peripapillary retinal nerve fiber layer(RNFL) thickness in eyes showing optic-disc...

Endogenous Endophthalmitis: yield of the diagnostic evaluation.

Apr 14, 2020

Endogenous endophthalmitis is an infection of the eye secondary to sepsis, occurring in 0.04-0.5% of bacteremia or fungemia. Risk factors include intravenous drug abuse (IVDA), diabetes, indwelling ca...

Prevalence of Subclinical Keratoconus Among Pediatric Egyptian Population with Astigmatism.

Apr 14, 2020

To report the prevalence of subclinical keratoconus (KC), and KC suspects, in pediatric Egyptian population with astigmatic error ≥2 diopters (D), with the use of CSO Sirius tomographer.A cross-sect...

Prediction models for development of retinopathy in people with type 2 diabetes: systematic review and external validation in a Dutch primary care setting.

Apr 07, 2020

The aims of this study were to identify all published prognostic models predicting retinopathy risk applicable to people with type 2 diabetes, to assess their quality and accuracy, and to validate the...

Implantable Self-Aligning Fiber-Optic Optomechanical Devices for in vivo Intraocular Pressure-Sensing in Artificial Cornea.

Apr 07, 2020

Artificial cornea is an effective treatment of corneal blindness. Yet, intraocular pressure (IOP) measurements for glaucoma monitoring remain an urgent unmet need. Here, we present the integration of ...

Targeting molecular pathways for the treatment of inherited retinal degeneration.

Apr 07, 2020

Inherited retinal degeneration is a major cause of incurable blindness characterized by loss of retinal photoreceptor cells. Inherited retinal degeneration is characterized by high genetic and phenoty...

Analysis of ocular surface damage and visual impact in patients with primary and secondary Sjögren syndrome.

Apr 07, 2020

The objective of this study is to review the ocular surface changes and complications of patients with Sjögren syndrome and assess their visual impact. A retrospective, cross-sectional, observational...

Mixed polar-nonpolar lipid films as minimalistic models of tear film lipid layer: A Langmuir trough and fluorescence microscopy study.

Apr 07, 2020

The Tear Film Lipid Layer (TFLL) covering the surface of the aqueous film at human cornea forms a first barrier between the eye and environment. Its alterations are related to dry eye disease. TFLL is...

Age Is a Determining Factor of Dry Eye-Related Signs and Symptoms.

Apr 07, 2020

The reported signs and symptoms of dry eye (DE) have been discordant. This study evaluated risk factors of DE-related symptoms and signs to explore their association with patient demographics, focusin...

Schirmer Paper Noninvasive Microsampling for Direct Mass Spectrometry Analysis of Human Tears.

Apr 07, 2020

Rapid and sensitive detection of metabolites and chemical residues in human tears is highly beneficial for understanding eye health. In this study, Schirmer paper was used for noninvasive microsamplin...

Reversibility of visual field defects through induction of brain plasticity: vision restoration, recovery and rehabilitation using alternating current stimulation.

Apr 07, 2020

For decades visual field defects were considered irreversible because it was thought that in the visual system the regeneration potential of the neuronal tissues is low. Nevertheless, there is always ...

Expression profiles of long noncoding RNAs in retinopathy of prematurity.

Apr 07, 2020

Long noncoding RNA (lncRNA) regulates the proliferation and migration of human retinal endothelial cells, as well as retinal neovascularization in diabetic retinopathy. Based on similarities between t...

Adipose-derived mesenchymal stromal cells reverse high glucose-induced reduction of angiogenesis in human retinal microvascular endothelial cells.

Apr 07, 2020

Diabetic retinopathy (DR) is characterized by a progressive alteration of the retinal microvasculature, arising from microaneurysms to leaky vessels and finally abnormal neovascularization. The hyperg...

Rebound Phenomenon after Intravitreal Injection of Triamcinolone Acetonide for Macular Edema.

Apr 07, 2020

To report on a rebound phenomenon after intravitreal triamcinolone acetonide (IVTA) injection for macular edema secondary to diabetic retinopathy (DR) and central or branch retinal vein occlusion (CRV...

The Relationship Between Intraocular Pressure and Rates of Central Versus Peripheral Visual Field Progression.

Apr 07, 2020

In this longitudinal prospective cohort study of open-angle glaucoma patients, intraocular pressure (IOP) parameters (mean, fluctuation, and maximum) had a similar effect on glaucomatous progression i...

Outcomes of Ahmed Glaucoma Drainage Implant in Eyes with Glaucoma Secondary to Iridocorneal Endothelial Syndrome.

Apr 07, 2020

To evaluate the success of Ahmed Glaucoma Valve Implantation (AGV) in patients with glaucoma secondary to Iridocorneal Endothelial (ICE) syndrome.This retrospective study included 18 eyes of 18 patien...

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