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Ophthalmology General

Prevalence of Subclinical Keratoconus Among Pediatric Egyptian Population with Astigmatism.

Apr 14, 2020

To report the prevalence of subclinical keratoconus (KC), and KC suspects, in pediatric Egyptian population with astigmatic error ≥2 diopters (D), with the use of CSO Sirius tomographer.A cross-sect...

Prediction models for development of retinopathy in people with type 2 diabetes: systematic review and external validation in a Dutch primary care setting.

Apr 07, 2020

The aims of this study were to identify all published prognostic models predicting retinopathy risk applicable to people with type 2 diabetes, to assess their quality and accuracy, and to validate the...

Implantable Self-Aligning Fiber-Optic Optomechanical Devices for in vivo Intraocular Pressure-Sensing in Artificial Cornea.

Apr 07, 2020

Artificial cornea is an effective treatment of corneal blindness. Yet, intraocular pressure (IOP) measurements for glaucoma monitoring remain an urgent unmet need. Here, we present the integration of ...

Targeting molecular pathways for the treatment of inherited retinal degeneration.

Apr 07, 2020

Inherited retinal degeneration is a major cause of incurable blindness characterized by loss of retinal photoreceptor cells. Inherited retinal degeneration is characterized by high genetic and phenoty...

Analysis of ocular surface damage and visual impact in patients with primary and secondary Sjögren syndrome.

Apr 07, 2020

The objective of this study is to review the ocular surface changes and complications of patients with Sjögren syndrome and assess their visual impact. A retrospective, cross-sectional, observational...

Mixed polar-nonpolar lipid films as minimalistic models of tear film lipid layer: A Langmuir trough and fluorescence microscopy study.

Apr 07, 2020

The Tear Film Lipid Layer (TFLL) covering the surface of the aqueous film at human cornea forms a first barrier between the eye and environment. Its alterations are related to dry eye disease. TFLL is...

Age Is a Determining Factor of Dry Eye-Related Signs and Symptoms.

Apr 07, 2020

The reported signs and symptoms of dry eye (DE) have been discordant. This study evaluated risk factors of DE-related symptoms and signs to explore their association with patient demographics, focusin...

Schirmer Paper Noninvasive Microsampling for Direct Mass Spectrometry Analysis of Human Tears.

Apr 07, 2020

Rapid and sensitive detection of metabolites and chemical residues in human tears is highly beneficial for understanding eye health. In this study, Schirmer paper was used for noninvasive microsamplin...

Reversibility of visual field defects through induction of brain plasticity: vision restoration, recovery and rehabilitation using alternating current stimulation.

Apr 07, 2020

For decades visual field defects were considered irreversible because it was thought that in the visual system the regeneration potential of the neuronal tissues is low. Nevertheless, there is always ...

Expression profiles of long noncoding RNAs in retinopathy of prematurity.

Apr 07, 2020

Long noncoding RNA (lncRNA) regulates the proliferation and migration of human retinal endothelial cells, as well as retinal neovascularization in diabetic retinopathy. Based on similarities between t...

Adipose-derived mesenchymal stromal cells reverse high glucose-induced reduction of angiogenesis in human retinal microvascular endothelial cells.

Apr 07, 2020

Diabetic retinopathy (DR) is characterized by a progressive alteration of the retinal microvasculature, arising from microaneurysms to leaky vessels and finally abnormal neovascularization. The hyperg...

Rebound Phenomenon after Intravitreal Injection of Triamcinolone Acetonide for Macular Edema.

Apr 07, 2020

To report on a rebound phenomenon after intravitreal triamcinolone acetonide (IVTA) injection for macular edema secondary to diabetic retinopathy (DR) and central or branch retinal vein occlusion (CRV...

The Relationship Between Intraocular Pressure and Rates of Central Versus Peripheral Visual Field Progression.

Apr 07, 2020

In this longitudinal prospective cohort study of open-angle glaucoma patients, intraocular pressure (IOP) parameters (mean, fluctuation, and maximum) had a similar effect on glaucomatous progression i...

Outcomes of Ahmed Glaucoma Drainage Implant in Eyes with Glaucoma Secondary to Iridocorneal Endothelial Syndrome.

Apr 07, 2020

To evaluate the success of Ahmed Glaucoma Valve Implantation (AGV) in patients with glaucoma secondary to Iridocorneal Endothelial (ICE) syndrome.This retrospective study included 18 eyes of 18 patien...

Assessment of primary open-angle glaucoma peripapillary and macular choroidal area using enhanced depth imaging optical coherence tomography.

Apr 07, 2020

The current study investigated differences in the peripapillary and macular choroidal areas between patients with primary open-angle glaucoma (POAG) and healthy controls because the choroid may potent...

The role of spatial selective attention in the processing of affective prosodies in congenitally blind adults: An ERP study.

Apr 07, 2020

The question whether spatial selective attention is necessary in order to process vocal affective prosody has been controversially discussed in sighted individuals: whereas some studies argue that att...

A systematic review of simulation-based training tools for technical and non-technical skills in ophthalmology.

Apr 07, 2020

To evaluate all simulation models for ophthalmology technical and non-technical skills training and the strength of evidence to support their validity and effectiveness. A systematic search was perfor...

Giant Cell Arteritis: The Experience of Two Collaborative Referral Centers and an Overview of Disease Pathogenesis and Therapeutic Advancements.

Apr 07, 2020

Giant cell arteritis (GCA), a chronic vasculitis of the large and medium-sized arteries, affects people >50 years of age. This study assessed the prevalence of visual manifestations and other clinical...

Association Between Sex Composition and Publication Productivity of Journal Editorial and Professional Society Board Members in Ophthalmology.

Apr 07, 2020

Because women remain underrepresented in leadership positions in medicine, including ophthalmology, knowledge of sex composition of ophthalmic journal editorial and professional society boards seems w...

Establishing a normative database for quantitative pupillometry in the pediatric population.

Apr 07, 2020

Pupillary evaluation is a crucial element of physical exams. Noting size, reactivity, and consensual response is critical in assessing for optic nerve dysfunction. We aim to establish normative data f...

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