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Ophthalmology General

Statins are associated with new onset type 2 diabetes mellitus (T2DM) in Medicare patients ≥65 years.

Mar 13, 2020

To evaluate the association of statins and co-morbidities with new onset type 2 diabetes mellitus (T2DM) in patients 65 years and older.This retrospective study used de-identified administrative hea...

Risks of ophthalmic disorders in patients with systemic lupus erythematosus - a secondary cohort analysis of population-based claims data.

Mar 13, 2020

Systemic lupus erythematosus (SLE) can directly affect various part of the ocular system, but there was no comprehensive analysis of ophthalmic disorders of patients with SLE using population-based da...

Sensory neurons directly promote angiogenesis in response to inflammation via substance P signaling.

Mar 13, 2020

Blood vessels and nerves travel together to supply most tissues in the body. However, there is a knowledge gap in the mechanisms underlying the direct regulation of angiogenesis by nerves. In the curr...

Relationship between lipid layer thickness, incomplete blinking rate and tear film instability in patients with different myopia degrees after small-incision lenticule extraction.

Mar 13, 2020

To elucidate the relationship between lipid layer thickness (LLT), incomplete blinking rate and tear film stability in patients with different myopia degrees after small-incision lenticule extraction ...

microRNA-499-3p inhibits proliferation and promotes apoptosis of retinal cells in diabetic retinopathy through activation of the TLR4 signaling pathway by targeting IFNA2.

Mar 13, 2020

microRNAs (miRNAs) are involved in the physiological and pathophysiological processes of diabetes and its microvascular and macrovascular complications. Hence, the aim of the study was to investigate ...

Auditory Input and Postural Control in Adults: A Narrative Review.

Mar 13, 2020

An increase in the number of mechanistic studies targeting the association between sound and balance has been observed in recent years, but their results appear equivocal.A search of PubMed and the Co...

Mood and behavior seasonality in glaucoma; assessing correlations between seasonality and structure and function of the retinal ganglion cells.

Mar 13, 2020

In glaucoma, depression and disturbed sleep has been associated with degeneration of the intrinsically photosensitive retinal ganglion cells, that mediate non-image forming effects of light such as re...

Focal lamina cribrosa defects and significant peripapillary choroidal thinning in patients with unilateral branch retinal vein occlusion.

Mar 13, 2020

To investigate the prevalence of focal lamina cribrosa (LC) defects in patients with unilateral branch retinal vein occlusion (BRVO) and to compare ocular characteristics between eyes with and without...

The importance of proper and prompt treatment of ocular syphilis: A lesson from permanent vision loss in 52 eyes.

Mar 13, 2020

Ocular involvement can occur at any stage of syphilis. Prompt diagnosis and proper treatment of ocular syphilis are vital to avoid long-term consequences.To describe the risk factors for ocular syphil...

Ease of hydrodissection during phacoemulsification: a comparison between patients with and without exfoliation syndrome.

Mar 13, 2020

Exfoliation syndrome (XFS), which is associated with increased surgical complications during phacoemulsification, has relatively high incidence in Greece. Multiannual surgical experience in XFS patien...

Anesthesia for Intravitreal Injection: A Systematic Review.

Mar 13, 2020

The intravitreal injection has become one of the most commonly performed procedures in ophthalmology; however, there is no standardized approach to anesthesia during the procedure. The goal of this sy...

Current Applicant Perceptions of the Ophthalmology Residency Match.

Mar 13, 2020

The ophthalmology residency application process is critical for applicants and residency programs, and knowledge about the preferences of applicants would assist both groups in improving the process.T...

Magnesium acetyltaurate protects against endothelin-1 induced RGC loss by reducing neuroinflammation in Sprague dawley rats.

Mar 12, 2020

Endothelin-1 (ET-1), a potent vasoconstrictor, plays a significant role in the pathophysiology of ocular conditions like glaucoma. Glaucoma is characterized by apoptotic loss of retinal ganglion cells...

Biomechanism of resistance to retinal injury in woodpecker's eyes.

Mar 12, 2020

Retinal injury is the most common ocular impairment associated with shaken baby syndrome (SBS), which could lead to vision loss and blindness. However, a woodpecker does not develop retinal hemorrhage...

A Multimodal Eye Assessment in Psoriatic Arthritis Patients -Psoriasis: Evidence for a Potential Association with Systemic Inflammation.

Mar 12, 2020

Ocular involvement in Psoriatic Arthritis (PsA) patients is mainly associated with uveitis but there remains a paucity of data on dry eye and retinal abnormalities. We aimed to analyze dry eye and sub...

Cryo-EM structure of the human PAC1 receptor coupled to an engineered heterotrimeric G protein.

Mar 12, 2020

Pituitary adenylate cyclase-activating polypeptide (PACAP) is a pleiotropic neuropeptide hormone. The PACAP receptor PAC1R, which belongs to the class B G-protein-coupled receptors (GPCRs), is a drug ...

[Osteo-odonto-keratoprosthesis: a tooth to regain sight].

Mar 12, 2020

As the leading cause of blindness in the world, corneal diseases are second only to cataracts. However, the epidemiology of corneal disease is complex and includes a wide variety of infectious and inf...

Inter-eye osmolarity differences in patients with symptomatic and non-symptomatic dry eyes.

Mar 12, 2020

To analyze whether inter-eye osmo larity differences were related to dry eye symptomatology.A total of 135 participants were randomly recruited from those who visited in the Optometry Clinic of the Op...

Predictors of Patient Satisfaction After Refractive Lens Exchange With an Extended Depth of Focus IOL.

Mar 12, 2020

To identify independent factors associated with postoperative satisfaction after refractive lens exchange with an extended depth of focus intraocular lens (EDOF IOL).Patients who underwent a refractiv...

Pediatric Diabetic Retinopathy: Experience of a Tertiary Hospital in Oman.

Mar 12, 2020

The aim of this study is to describe the prevalence and clinical profile of pediatric diabetic retinopathy (DR) among Omani diabetic children and adolescents attending a tertiary care hospital.This re...

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