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Ophthalmology General

Prevalence and Severity of Diabetic Retinopathy among Diabetic Patients Presenting to a Tertiary Eye Hospital in Nepal.

Mar 12, 2020

The purpose of the study is to evaluate the prevalence and severity of diabetic retinopathy (DR) among all diabetic patients presenting to a tertiary eye care center in Nepal over a 3-year period.This...

Endocannabinoids in aqueous humour of patients with or without diabetes.

Mar 12, 2020

The primary aim was to determine endocannabinoid (EC) concentrations of 2-arachidonoylglycerol (2-AG), oleoylethanolamine (OEA), palmitoylethanolamine (PEA) and anandamide (AEA) in the aqueous humour ...

Ability of Swept source OCT technology to detect neurodegeneration in patients with type 2 diabetes mellitus without diabetic retinopathy.

Mar 12, 2020

To evaluate neurodegeneration in patients with type 2 Diabetes Mellitus (DM2) without diabetic retinopathy, and to assess the possible role of chronic systemic ischaemia and disease duration in retina...

Association of the Somatostatin Analog Octreotide With Magnetic Nanoparticles for Intraocular Delivery: A Possible Approach for the Treatment of Diabetic Retinopathy.

Mar 12, 2020

The somatostatin analog octreotide (OCT) displays important neuroprotective and anti-angiogenic properties that could make it an interesting candidate to treat diabetic retinopathy (DR). Unfortunately...

Causes of congenital corneal opacities and their management in a tertiary care center.

Mar 12, 2020

To evaluate causes and management of congenital corneal opacities (CCO) diagnosed in a tertiary care eye center and to compare the data with a previous study at the same institution.Computerized medic...

Regression of macular edema with topical brinzolamide and nepafenac alone and identification of a novel gyrate atrophy mutation.

Mar 12, 2020

Gyrate atrophy is a rare metabolic autosomal recessive disorder caused by ornithine aminotransferase enzyme deficiency that leads to characteristic progressive, degenerative chorioretinal findings. Pa...

Corrosion resistance of a Nitinol ocular microstent: Implications on biocompatibility.

Mar 12, 2020

Nitinol is commonly used in medical implants due to its unique thermomechanical properties of shape memory and superelasticity. Free nickel has the potential to induce biological responses that may be...

Watch this space: a systematic review of the use of video-based media as a patient education tool in ophthalmology.

Mar 12, 2020

Effective clinician-patient communication is particularly important in ophthalmology where long-term adherence to treatment is often required. However, in the context of increasingly pressurised clini...

Development and Characterization of a Benchtop Corneal Puncture Injury Model.

Mar 09, 2020

During recent military operations, eye-related injuries have risen in frequency due to increased use of explosive weaponry which often result in corneal puncture injuries. These have one of the poores...

Data-driven modelling and spatial complexity supports heterogeneity-based integrative management for eliminating Simulium neavei-transmitted river blindness.

Mar 09, 2020

Concern is emerging regarding the challenges posed by spatial complexity for modelling and managing the area-wide elimination of parasitic infections. While this has led to calls for applying heteroge...

Deployed ophthalmic workload in support of US and NATO operations in Afghanistan.

Mar 09, 2020

The extent and types of ophthalmic disease and non-battle injury (DNBI) seen by expeditionary ophthalmologists at deployed military medical treatment facilities have not previously been reported. We a...

Analysis of factors leading to lid wiper epitheliopathy.

Mar 09, 2020

Lid wiper epitheliopathy (LWE) has received more attention during the diagnosis and treatment of the dry eye. However, its causes and pathogenesis remain unclear. We aimed to explore the etiology of L...

Agreement and repeatability of four different devices to measure non-invasive tear breakup time (NIBUT).

Mar 09, 2020

Since tear film stability can be affected by fluorescein, the Dry Eye Workshop (DEWSII) recommended non-invasive measurement of tear breakup time (NIBUT). The aim of this study was to investigate the ...

The effect of sodium fluorescein on anterior eye surface measurements.

Mar 09, 2020

During image acquisition, certain topographers require the addition of sodium fluorescein (NaFl) dye to the tear film. This study investigates the effect of NaFl dye on corneal topography and tear sur...

Comparison of true-colour wide-field confocal scanner imaging with standard fundus photography for diabetic retinopathy screening.

Mar 09, 2020

Screening of diabetic retinopathy (DR) reduces blindness by early identification of retinopathy. This study compares DR grades derived from a two-field imaging protocol from two imaging platforms, one...

Activation of retinal angiogenesis in hyperglycemic zebrafish mutants.

Mar 09, 2020

Progression from the initial vascular response upon hyperglycemia to a proliferative stage with neovacularizations is the hallmark of proliferative diabetic retinopathy. Here we report on the novel di...

Antagonist of nucleolin, N6L, inhibits neovascularization in mouse models of retinopathies.

Mar 09, 2020

Retinal vascular diseases (RVD) have been identified as a major cause of blindness worldwide. These pathologies, including the wet form of age-related macular degeneration, retinopathy of prematurity,...

Treatment of diabetic retinopathy through neuropeptide Y-mediated enhancement of neurovascular microenvironment.

Mar 09, 2020

Diabetic retinopathy (DR) is one of the most severe clinical manifestations of diabetes mellitus and a major cause of blindness. DR is principally a microvascular disease, although the pathogenesis al...

Association between community outpatient clinic care accessibility and the uptake of diabetic retinopathy screening: A multi-level analysis.

Mar 09, 2020

To investigate the uptake rate variance of fundus examination for diabetes-related complications among demographically and geographically diverse communities and examine determinants that influence th...

The prevalence of uveitis in a population of donkeys in the UK.

Mar 09, 2020

Uveitis is a leading cause of blindness in horses. Little work has been undertaken to investigate whether donkeys are affected by a similar disease prevalence.To investigate the disease prevalence of ...

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