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Ophthalmology General

Treatment of diabetic retinopathy through neuropeptide Y-mediated enhancement of neurovascular microenvironment.

Mar 09, 2020

Diabetic retinopathy (DR) is one of the most severe clinical manifestations of diabetes mellitus and a major cause of blindness. DR is principally a microvascular disease, although the pathogenesis al...

Association between community outpatient clinic care accessibility and the uptake of diabetic retinopathy screening: A multi-level analysis.

Mar 09, 2020

To investigate the uptake rate variance of fundus examination for diabetes-related complications among demographically and geographically diverse communities and examine determinants that influence th...

The prevalence of uveitis in a population of donkeys in the UK.

Mar 09, 2020

Uveitis is a leading cause of blindness in horses. Little work has been undertaken to investigate whether donkeys are affected by a similar disease prevalence.To investigate the disease prevalence of ...

Lipofilling of the upper eyelid to treat paralytic lagophthalmos.

Mar 09, 2020

Lagophthalmos is one of the most unpleasant and dangerous conditions that affect patients with facial palsy. The lack of ocular protection leads to corneal problems (such as conjunctival infections, a...

Albrecht von Graefe in the present, the past, and the future.

Mar 09, 2020

Albrecht von Graefe (1828-1870) is the founder of this archive (1854) and the founder of modern ophthalmology. In 2020, the anniversary of his death will be observed for the 150th time. The "German Op...

Diagnostic power of scleral spur length in primary open-angle glaucoma.

Mar 09, 2020

To investigate the diagnostic capability of scleral spur length in discriminating eyes with primary open-angle glaucoma (POAG) from healthy eyes.Seventy-eight eyes of 78 patients with POAG and 93 eyes...

Vitrectomy with or without internal limiting membrane peeling for myopic foveoschisis.

Mar 09, 2020

The aim of this study was to compare the anatomical and visual outcomes of vitrectomy with or without internal limiting membrane (ILM) peeling for symptomatic myopic foveoschisis (MF).A retrospective ...

Pediatric ocular trauma: Characteristics and outcomes among a French cohort (2007-2016).

Mar 05, 2020

Pediatric ocular trauma is a major cause of acquired monocular blindness. Post-traumatic visual impairment can lead to significant handicap. In France, recent data on the epidemiology of pediatric ocu...

Validation and reliability of the Turkish version of Contact Lens Dry Eye Questionnaire-8 (CLDEQ-8).

Mar 05, 2020

Contact lens dry eye questionnaire-8 (CLDEQ-8) quantifies the disturbing symptoms with the aim of assessing the satisfaction and overall opinion of contact lens wearers. The aim of this study was to d...

Association between Dry Eye and Depressive Symptoms: Large-Scale Crowdsourced Research Using the DryEyeRhythm iPhone Application.

Mar 05, 2020

Dry eye (DE) disease and depression are increasing in modern times. We investigated the association between DE and depressive symptoms using the iPhone application, DryEyeRhythm.This large-scale crowd...

High-fat diet induces dry eye-like ocular surface damages in murine.

Mar 05, 2020

A high-fat diet leads to dysfunction in multiple systems of the body. Herein we investigate the effects of a high-fat diet on the ocular surface using a murine model.Four-week-old male C57BL/6 mice we...

Management of moderate-to-severe dry eye disease using chitosan-N-acetylcysteine (Lacrimera®) eye drops: a retrospective case series.

Mar 05, 2020

Dry eye disease is a highly prevalent condition that causes tear film instability, ocular discomfort, and visual disturbance. Lacrimera eye drops are approved for the short-term treatment of dry eye d...

Explanatory Model of Dry Eye Disease Using Health and Nutrition Examinations: Machine Learning and Network-Based Factor Analysis From a National Survey.

Mar 05, 2020

Dry eye disease (DED) is a complex disease of the ocular surface, and its associated factors are important for understanding and effectively treating DED.This study aimed to provide an integrative and...

Risk factors for dropped nucleus in cataract surgery as reflected by the European Registry of Quality Outcomes for Cataract and Refractive Surgery.

Mar 05, 2020

To analyze the incidence, risk factors, and outcomes of cataract surgery complicated by a dropped nucleus.Patients who have received cataract surgery in 18 European countries.Retrospective cross-secti...

Health-related quality of life and health utilities in insulin-treated type 2 diabetes: the impact of related comorbidities/complications.

Mar 05, 2020

To evaluate the impact of multiple comorbidities/complications on health-related quality of life (HRQoL) and health utilities in insulin-treated type 2 diabetes (T2DM).In a non-interventional, epidemi...

TRPV4 Channels as Therapeutic Targets in Diabetes and Diabetes-related Complications.

Mar 05, 2020

With an estimated 425 million diabetic patients worldwide in 2019, type 2 diabetes (T2D) has reached a pandemic proportion and represents a major unmet medical need. A key determinant of the developme...

Epigenetic silencing of heat shock protein 70 through DNA hypermethylation in pseudoexfoliation syndrome and glaucoma.

Mar 05, 2020

This study is intended to investigate the epigenetic regulation of the most conserved molecular chaperone, HSP70 and its potential role in the pathophysiology of pseudoexfoliation syndrome (PEXS) and ...

Factors associated with trachoma treatment and control treatment in schools of municipality of the Northeast Region, Brazil.

Mar 05, 2020

Trachoma maintains itself as a public health problem and an important cause of morbidity, visual impairment and preventable blindness in Brazil.To analyze factors associated with treatment and control...

The Role of Catecholamines in the Development of Pathological Retina Neovascularization in an Experimental Model of Retinopathy of Prematurity in Rats.

Mar 05, 2020

This work is dedicated to proving our hypothesis that catecholamines and their metabolites play a crucial role in the development of retinopathy of prematurity, which leads to progressive uncontrollab...

Intraocular Pressure Elevation in Keratoconus with Coexisting Pseudoexfoliation Glaucoma: How Important is the Method of Measurement?

Mar 05, 2020

In this report, we investigated the association between the intraocular pressure (IOP) values by two different measurement methods and the corneal biomechanical properties in a patient with keratoconu...

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