Mar 05, 2020

A high-fat diet leads to dysfunction in multiple systems of the body. Herein we investigate the effects of a high-fat diet on the ocular surface using a murine model.Four-week-old male C57BL/6 mice we...

Mar 05, 2020

Dry eye disease is a highly prevalent condition that causes tear film instability, ocular discomfort, and visual disturbance. Lacrimera eye drops are approved for the short-term treatment of dry eye d...

Mar 05, 2020

Dry eye disease (DED) is a complex disease of the ocular surface, and its associated factors are important for understanding and effectively treating DED.This study aimed to provide an integrative and...

Mar 05, 2020

To analyze the incidence, risk factors, and outcomes of cataract surgery complicated by a dropped nucleus.Patients who have received cataract surgery in 18 European countries.Retrospective cross-secti...

Mar 05, 2020

To evaluate the impact of multiple comorbidities/complications on health-related quality of life (HRQoL) and health utilities in insulin-treated type 2 diabetes (T2DM).In a non-interventional, epidemi...

Mar 05, 2020

With an estimated 425 million diabetic patients worldwide in 2019, type 2 diabetes (T2D) has reached a pandemic proportion and represents a major unmet medical need. A key determinant of the developme...

Mar 05, 2020

This study is intended to investigate the epigenetic regulation of the most conserved molecular chaperone, HSP70 and its potential role in the pathophysiology of pseudoexfoliation syndrome (PEXS) and ...

Mar 05, 2020

Trachoma maintains itself as a public health problem and an important cause of morbidity, visual impairment and preventable blindness in Brazil.To analyze factors associated with treatment and control...

Mar 05, 2020

This work is dedicated to proving our hypothesis that catecholamines and their metabolites play a crucial role in the development of retinopathy of prematurity, which leads to progressive uncontrollab...

Mar 05, 2020

In this report, we investigated the association between the intraocular pressure (IOP) values by two different measurement methods and the corneal biomechanical properties in a patient with keratoconu...

Mar 05, 2020

There is only limited information available on the effects of physical exercise on the posterior pole. Retinal circulation is autoregulated similarly to the brain vasculature in order to provide const...

Mar 02, 2020

Old age is often associated with functional decline and physical dependence, thus compromising the ability to carry out basic tasks required for daily living. There are very few community-based studie...

Mar 02, 2020

Cataract is the major reason for human blindness worldwide. α-Crystallin, as a key chaperone of eye lenses, keeps the lenticular tissues in its transparent state over time. In this study, cataract-ca...

Mar 02, 2020

To review the role of antigen-presenting cells (APC) in the pathogenesis of ocular surface diseases (OSD).A thorough literature search was performed in PubMed database. An additional search was made i...

Mar 02, 2020

Several blood derivatives have been proposed for the treatment of various ocular diseases that affect either the anterior or the posterior segment of the eye. Blood sources may range from the patient'...

Mar 02, 2020

Certain diabetic and hypertensive patients started on intravitreal vascular endothelial growth factor inhibition for diabetic retinopathy may experience worsening of hypertension and proteinuria. The ...

Mar 02, 2020

To evaluate change in best-corrected visual acuity (BCVA) in patients with diabetes and diabetic retinopathy (DR) after cataract extraction (CE).Retrospective cohort study.Diabetic eyes of patients 18...

Mar 02, 2020

To compare microaneurysm (MA) counts using ultrawide field colour images (UWF-CI) and ultrawide field fluorescein angiography (UWF-FA).Retrospective study including patients with type 1 or 2 diabetes ...

Mar 02, 2020

This research aimed to investigate whether diabetic blood-stasis syndrome had a relationship with ROS-ERK1/2 signaling pathway in rat retina Müller cells and explore the effects of traditional Chines...

Mar 02, 2020

Despite safety concerns, β-sympathomimetics are still widely used as tocolytic agents. β-Blockers in turn are used to treat vasculo-proliferative diseases of the newborn such as retinopathy of prema...