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Ophthalmology General

The Effect of Physical Exercise on the Retina and Choroid.

Mar 05, 2020

There is only limited information available on the effects of physical exercise on the posterior pole. Retinal circulation is autoregulated similarly to the brain vasculature in order to provide const...

Functional disability among elderly: A community-based cross-sectional study.

Mar 02, 2020

Old age is often associated with functional decline and physical dependence, thus compromising the ability to carry out basic tasks required for daily living. There are very few community-based studie...

The congenital cataract-causing mutations P20R and A171T are associated with important changes in the amyloidogenic feature, structure and chaperone-like activity of human αB-crystallin.

Mar 02, 2020

Cataract is the major reason for human blindness worldwide. α-Crystallin, as a key chaperone of eye lenses, keeps the lenticular tissues in its transparent state over time. In this study, cataract-ca...

Antigen-presenting cells in ocular surface diseases.

Mar 02, 2020

To review the role of antigen-presenting cells (APC) in the pathogenesis of ocular surface diseases (OSD).A thorough literature search was performed in PubMed database. An additional search was made i...

Umbilical Cord Blood and Serum for the Treatment of Ocular Diseases: A Comprehensive Review.

Mar 02, 2020

Several blood derivatives have been proposed for the treatment of various ocular diseases that affect either the anterior or the posterior segment of the eye. Blood sources may range from the patient'...

Intravitreal bevacizumab-induced exacerbation of proteinuria in diabetic nephropathy, and amelioration by switching to ranibizumab.

Mar 02, 2020

Certain diabetic and hypertensive patients started on intravitreal vascular endothelial growth factor inhibition for diabetic retinopathy may experience worsening of hypertension and proteinuria. The ...

Visual Acuity Outcomes after Cataract Extraction with Intraocular Lens Implantation in Eyes with Diabetic Retinopathy.

Mar 02, 2020

To evaluate change in best-corrected visual acuity (BCVA) in patients with diabetes and diabetic retinopathy (DR) after cataract extraction (CE).Retrospective cohort study.Diabetic eyes of patients 18...

Disparity of microaneurysm count between ultrawide field colour imaging and ultrawide field fluorescein angiography in eyes with diabetic retinopathy.

Mar 02, 2020

To compare microaneurysm (MA) counts using ultrawide field colour images (UWF-CI) and ultrawide field fluorescein angiography (UWF-FA).Retrospective study including patients with type 1 or 2 diabetes ...

Effect of diabetes blood-stasis syndrome and Xuefu Zhuyu decoction on ROS-ERK1/2 signaling pathway in rat retina Müller cells.

Mar 02, 2020

This research aimed to investigate whether diabetic blood-stasis syndrome had a relationship with ROS-ERK1/2 signaling pathway in rat retina Müller cells and explore the effects of traditional Chines...

Antenatal exposure to fenoterol is not associated with the development of retinopathy of prematurity in infants born before 32 weeks of gestation.

Mar 02, 2020

Despite safety concerns, β-sympathomimetics are still widely used as tocolytic agents. β-Blockers in turn are used to treat vasculo-proliferative diseases of the newborn such as retinopathy of prema...

Systemic and ocular determinants of mean ocular perfusion pressure in a population-based sample.

Mar 02, 2020

To investigate the associations between mean ocular perfusion pressure (MOPP) and several variables including body mass index (BMI), comorbid medical conditions and various ocular parameters in a popu...

[Endophthalmitis after perforation of the conjunctiva by a glaucoma gel-stent implant].

Mar 02, 2020

Intraocular infections associated with Abiotrophia defectiva are rare. This article reports the case of a 57-year-old woman with endophthalmitis associated with Abiotrophia defectiva 3 months after u...

Ten-year outcomes of anti-vascular endothelial growth factor treatment for neovascular age-related macular disease: a single center French study.

Mar 02, 2020

Long-term data of intravitreal injections of vascular endothelial growth factor (VEGF) inhibitors are lacking.This study aims to assess visual and anatomic outcomes of eyes with neovascular age-relate...

Zinc oxide nanoparticles induce human tenon fibroblast apoptosis through reactive oxygen species and caspase signaling pathway.

Mar 02, 2020

Glaucoma is the leading cause of irreversible blindness in the world and trabeculectomy remains still the most commonly performed filtration surgery. Failure of trabeculectomy is due to the formation ...

Vitreoretinal Interface Slab in OCT Angiography for Detecting Diabetic Retinal Neovascularization.

Mar 02, 2020

To compare neovascularization identified in proliferative diabetic retinopathy (PDR) eyes by widefield swept-source (SS) OCT angiography (OCTA) using vitreoretinal interface (VRI) slab images, compose...

Intraoperative Floppy Iris Syndrome: Updated Perspectives.

Mar 02, 2020

Almost fifteen years since its initial description, intraoperative floppy iris syndrome (IFIS) during phacoemulsification surgery remains a challenge for cataract surgeons in all its key aspects that ...

Direct OPTOS Nerve Size Determination of Prevalent Optic Nerve Hypoplasia in Alaska.

Mar 02, 2020

Optic nerve hypoplasia (ONH), one of the most common causes of pediatric blindness in developed countries, has been difficult to directly quantify. We sought to measure optic nerve size in Alaskan ped...

Resetting outcome targets of community surgery camps: The case of the Chhattisgarh tragedy.

Feb 28, 2020

State-driven community surgery camps have been organised in India for nearly five decades. Despite their being extremely beneficial to people not having ready access to surgical healthcare (SHC), they...

Research progress of in-situ gelling ophthalmic drug delivery system.

Feb 28, 2020

Blindness and vision impairment are the most devastating global health problems resulting in a substantial economic and social burden. Delivery of drug to particular parts of the anterior or posterior...

Associations Between Systemic Omega-3 Fatty Acid Levels With Moderate-to-Severe Dry Eye Disease Signs and Symptoms at Baseline in the Dry Eye Assessment and Management Study.

Feb 28, 2020

Omega-3 (n-3) fatty acid supplementation is used to treat systemic inflammatory diseases, but the role of n-3 in the pathophysiology and therapy of dry eye disease (DED) is not definitive. We evaluate...

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