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Ophthalmology General

US Population Disparities in Ophthalmic Care: Blindness and Visual Impairment in the IRIS® Registry (Intelligent Research In Sight).

Jun 19, 2023

To evaluate associations of patient characteristics with United States eyecare utilization and likelihood of blindness.Retrospective observational study.19,546,016 patients with 2018 visual acuity (VA...

Race, Ethnicity, Insurance and Population Density Associations with Pediatric Strabismus and Strabismic Amblyopia in the IRIS® Registry.

Jun 19, 2023

To evaluate associations of socio-demographic factors with pediatric strabismus diagnosis and outcomes.Retrospective cohort study.American Academy of Ophthalmology IRIS® Registry (Intelligent Researc...

Association of long-term exposure to ambient air pollution with retinal neurodegeneration: The prospective alienor study.

Jun 12, 2023

Chronic exposure to air pollution may have adverse effects on neurodegenerative diseases. Glaucoma, the second leading cause of blindness worldwide, is a neurodegenerative disease of the optic nerve, ...

Effect of Midface Surgery on Ocular Outcomes in Patients with Orbital and Midface Malformations.

Jun 12, 2023

(1) Background: Orbital and midface malformations occur in multiple craniofacial disorders. Depending on the deformity, surgical corrections include orbital box osteotomy (OBO), Le Fort III (LFIII), m...

Outcomes of standalone ab interno trabeculotomy in the treatment of open-angle glaucoma in eyes with high myopia.

Jun 12, 2023

We retrospectively evaluate the long-term efficacy and safety of trabeculotomy glaucoma surgery in treating open-angle glaucoma (OAG) in eyes with high myopia (HM).This study included 20 eyes with HM ...

Salidroside alleviates oxidative stress in dry eye disease by activating autophagy through AMPK-Sirt1 pathway.

Jun 12, 2023

Dry eye disease (DED) is a multifactorial disease, and oxidative stress plays a crucial role in its pathogenesis. Recently, multiple studies have shown that upregulation of autophagy can protect the c...

Gut microbiota and metabolites in diabetic retinopathy: Insights into pathogenesis for novel therapeutic strategies.

Jun 12, 2023

Diabetic retinopathy (DR) is the most common and detrimental microvascular complication of diabetes mellitus. It has become one of the top causes of blindness and visual impairment in the working-age ...

Clinical evaluation and management of badminton-related eye injuries: a retrospective case series.

Jun 12, 2023

To describe the clinical features, visual outcomes, management, and complications of ocular injury in badminton and investigate risk factors associated with visual impairment.Data on patients injured ...

Cystoid Macular Edema After Cataract Surgery in the United States: IRIS® Registry (Intelligent Research in Sight) Analysis.

Jun 12, 2023

To determine the incidence, risk factors, and visual outcomes of cystoid macular edema (CME) after cataract surgery in the United States.Retrospective longitudinal case-control study.Patients ≥18 ye...

Prevalence of visual impairment and availability of eye care providers in Florida.

Jun 05, 2023

To determine the association between prevalence of visual impairment and density of eye care providers in Florida counties.Cross-sectional study.SETTING: Population-based STUDY POPULATION: Ophthalmolo...

Analysis of biometric parameters of cataract eyes measured with optical biometer Lenstar LS900, IOL Master 700, and OPD-SCAN III.

Jun 05, 2023

To compare the characteristics of biometric measurements among the LS900, IOL Master, and OPD-SCAN III in patients with mild-to-moderate cataract.We recruited 85 eyes of 78 patients diagnosed with mil...

IgA nephropathy with minimal change disease associated with primary Sjögren's syndrome: A case report.

Jun 05, 2023

Only 1 case of IgA nephropathy (IgAN) with minimal change disease (MCD) associated with primary Sjögren's syndrome (SS) has been reported. We additionally describe IgAN with MCD associated with prima...

Hyperosmolarity promotes macrophage pyroptosis by driving the glycolytic reprogramming of corneal epithelial cells in dry eye disease.

Jun 05, 2023

Tear film hyperosmolarity plays a core role in the development of dry eye disease (DED) by mediating the disruption of ocular surface homeostasis and triggering inflammation in ocular surface epitheli...

Inner Retinal Thickness and Vasculature in Patients with Reticular Pseudodrusen.

Jun 05, 2023

To investigate retinal layer thickness and vessel density differences between patients with reticular pseudodrusen (RPD) and intermediate dry age-related macular degeneration (iAMD).Participants inclu...

Quantitatively evaluating the relationships between insulin resistance and retinal neurodegeneration with optical coherence tomography in early type 2 diabetes mellitus.

Jun 05, 2023

To quantitatively assess retinal neurodegenerative changes with optical coherence tomography (Cirrus HD-OCT) in type 2 diabetes mellitus (T2DM) patients without diabetic retinopathy (DR), and evaluate...

Macular Retinoschisis from Optic Disc Without a Visible Optic Pit or Advanced Glaucomatous Cupping (No Optic Pit Retinoschisis [NOPIR]).

Jun 05, 2023

To review eyes with peripapillary and macular retinoschisis without a visible optic pit or advanced glaucomatous optic atrophy, or NOPIR (No Optic Pit Retinoschisis) DESIGN: Retrospective multi-center...

Bibliometric Analysis of Ophthalmic Journals.

Jun 05, 2023

The primary vehicle for reporting and testing advances in eye care is refereed ophthalmic journals, which can be characterized using targeted bibliometric analyses.To identify all ophthalmic journals ...

Improved Detection of Dry Age-Related Macular Degeneration from Optical Coherence Tomography Images using Adaptive Window Based Feature Extraction and Weighted Ensemble Based Classification Approach.

May 29, 2023

Dry Age-related macular degeneration (AMD), which affects the older population, can lead to blindness when left untreated. Preventing vision loss in elderly needs early identification. Dry-AMD diagnos...

Corneal gene therapy: Structural and mechanistic understanding.

May 29, 2023

Cornea, a dome-shaped and transparent front part of the eye, affords 2/3rd refraction and barrier functions. Globally, corneal diseases are the leading cause of vision impairment. Loss of corneal func...

A case report: Marfan syndrome with X trisomy and FBN1 and SDHB mutations.

May 29, 2023

Marfan syndrome (MFS) is a rare autosomal dominant connective tissue disorder affecting the cardiovascular, skeletal, and ophthalmic systems. This report aimed to describe a novel genetic background a...

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