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Ophthalmology General

Ocular surface and meibomian gland evaluation in euthyroid Graves' ophthalmopathy.

Mar 04, 2024

Euthyroid Graves' ophthalmology (EGO) refers to the subgroup of thyroid eye disease patients with distinct clinical presentations. This study evaluated the ocular surface and meibomian gland changes i...

Saikosaponin F ameliorates depression-associated dry eye disease by inhibiting TRIM8-induced TAK1 ubiquitination.

Mar 04, 2024

Saikosaponin F (SsF) is one of the major active ingredients of Radix Bupleuri, an herb widely used in the treatment of depression. Studies have shown that dry eye disease often occurs together with de...

Glucose tolerance and insulin resistance/sensitivity associate with retinal layer characteristics: the LIFE-Adult-Study.

Mar 04, 2024

As the prevalence of insulin resistance and glucose intolerance is increasing throughout the world, diabetes-induced eye diseases are a global health burden. We aim to identify distinct optical bands ...

Determinants of non-diabetic kidney diseases in type 2 diabetic patients: Twenty years of single center experience.

Mar 04, 2024

Diabetic nephropathy is one of the most common complications associated with diabetes. However, non-diabetic kidney disease has been reported in patients with type 2 diabetes at varying incidence rate...

Evaluating the accuracy of the Ophthalmologist Robot for multiple blindness-causing eye diseases: a multicentre, prospective study protocol.

Mar 04, 2024

Early eye screening and treatment can reduce the incidence of blindness by detecting and addressing eye diseases at an early stage. The Ophthalmologist Robot is an automated device that can simultaneo...

Circadian rhythm of intraocular pressure.

Mar 04, 2024

Intraocular pressure (IOP) plays a crucial role in glaucoma development, involving the dynamics of aqueous humor (AH). AH flows in from the ciliary body and exits through the trabecular meshwork (TM)....

Accuracy of an Artificial Intelligence Chatbot's Interpretation of Clinical Ophthalmic Images.

Mar 04, 2024

Ophthalmology is reliant on effective interpretation of multimodal imaging to ensure diagnostic accuracy. The new ability of ChatGPT-4 (OpenAI) to interpret ophthalmic images has not yet been explored...

How Can Artificial Intelligence Be Implemented Effectively in Diabetic Retinopathy Screening in Japan?

Feb 26, 2024

Diabetic retinopathy (DR) is a major microvascular complication of diabetes, affecting a substantial portion of diabetic patients worldwide. Timely intervention is pivotal in mitigating the risk of bl...

Ultra-Wide-Field Optical Coherence Tomography and Gaussian Curvature to Assess Macular and Paravascular Retinoschisis in High Myopia.

Feb 26, 2024

To evaluate the severity and related factors of macular retinoschisis (MRS) and paravascular retinoschisis (PVRS) in high myopia (HM) using ultra-wide-field optical coherence tomography (UWF-OCT) and ...

Effect of capsular tension ring on the refractive outcomes of patients with extreme high axial myopia after phacoemulsification.

Feb 26, 2024

The aim of the study is to evaluate the effect of capsular tension ring (CTR) implantation following cataract surgery on the refractive outcomes of patients with extreme high axial myopia.Sixty eyes (...

Enhancing Ocular Surface in Dry Eye Disease Patients: A Clinical Evaluation of a Topical Formulation Containing Sesquiterpene Lactone Helenalin.

Feb 26, 2024

The aim of this work was to assess the tolerability, safety, and efficacy of an ophthalmic topical formulation containing helenalin from and hyaluronic acid 0.4% (HA) in patients with mild-to-moderat...

Efficacy and Safety of Artificial Tears Containing Lipidure and Hypromellose for the Treatment of Moderate Dry Eye Disease in Contact Lens Wearers.

Feb 26, 2024

: Dry eye disease (DED) affects 5-50% of the global population and deeply influences everyday life activities. This study compared the efficacy, tolerability, and safety of novel Respilac artificial t...

Ocular microvascular alteration in patients with myocardial infarction-a new OCTA study.

Feb 26, 2024

Myocardial infarction is defined as a sudden decrease or interruption in blood flow to the coronary arteries, causing ischemic necrosis of the corresponding cardiomyocytes. It is unclear whether syste...

Macula vs periphery in diabetic retinopathy: OCT-angiography and ultrawide field fluorescein angiography imaging of retinal non perfusion.

Feb 26, 2024

To investigate the association between peripheral non-perfusion index (NPI) on ultrawide-field fluorescein angiography (UWF-FA) and quantitative OCT-Angiography (OCT-A) metrics in the macula.In total,...

A comparative analysis of IOP measurement accuracy with reused iCare probes.

Feb 26, 2024

To assess the accuracy of reused iCare probes after disinfection with 70% isopropyl alcohol and ethylene glycol compared to new iCare probes and Goldmann Applanation Tonometry (GAT).Prospective compar...

Effectiveness and safety of XEN63 in patients with primary-open-angle glaucoma.

Feb 26, 2024

This paper evaluates the effectiveness and safety of XEN63 stent, either standalone or in combination with phacoemulsification, in patients with primary open-angle glaucoma (POAG). Eighty eyes from 80...

Assessment of a Large Language Model's Responses to Questions and Cases About Glaucoma and Retina Management.

Feb 26, 2024

Large language models (LLMs) are revolutionizing medical diagnosis and treatment, offering unprecedented accuracy and ease surpassing conventional search engines. Their integration into medical assist...

Comparison of early changes in tear film protein profiles after small incision lenticule extraction (SMILE) and femtosecond LASIK (FS-LASIK) surgery.

Feb 19, 2024

Small incision lenticule extraction (SMILE) and femtosecond laser-assisted in situ keratomileusis (LASIK) are widely used surgical methods to correct myopia with comparable efficacy, predictability, a...

Evaluation of Dry Eye Severity and Ocular Surface Inflammation in Patients with Autoimmune Rheumatic Diseases.

Feb 19, 2024

To evaluate dry eye severity and ocular surface inflammation in autoimmune rheumatic diseases (ARDs).Seventy-nine patients with ARDs were enrolled, including 26 patients with rheumatoid arthritis (RA)...

Resilient back-propagation machine learning-based classification on fundus images for retinal microaneurysm detection.

Feb 19, 2024

The timely diagnosis of medical conditions, particularly diabetic retinopathy, relies on the identification of retinal microaneurysms. However, the commonly used retinography method poses a challenge ...

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