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Ophthalmology General

Study on HSPGs of the Ocular Lens: Functions and Implications

Apr 04, 2023

The following is a summary of the “Heparan sulfate proteoglycans (HSPGs) of the ocular lens,” published in the March 2023 issue of Progress in retinal and eye research by Wishart, et al. Mo...

Study of the Visionary Light-sensor Rhodopsin

Apr 03, 2023

The following is a summary of the “Rhodopsin, light-sensor of vision,” published in the March 2023 issue of Progress in retinal and eye research by Hofmann, et al. Rhodopsin is a G-protein-...

The adhesion G-protein-coupled receptor VLGR1/ADGRV1 controls autophagy.

Apr 03, 2023

VLGR1/ADGRV1 (very large G protein-coupled receptor-1) is the largest known adhesion G protein-coupled receptor. Mutations in VLGR1/ADGRV1 cause Usher syndrome (USH), the most common form of hereditar...

Sigma 1 receptor activation improves retinal structure and function in the Rho mouse model of autosomal dominant retinitis pigmentosa.

Apr 03, 2023

Retinitis pigmentosa (RP) is a group of devastating inherited retinal diseases that leads to visual impairment and oftentimes complete blindness. Currently no cure exists for RP thus research into pro...

Elevated Neuropeptides in Dry Eye Disease and Their Clinical Correlations.

Apr 03, 2023

The goal of this study was to assess neuropeptide levels in patients with dry eye disease (DED) and investigate their correlations with clinical characteristics.This study included 38 eyes of 38 patie...

The epidemiology of dry eye disease in the UK: The Aston dry eye study.

Apr 03, 2023

Cross-sectional studies on dry eye disease (DED) have relied on different diagnoses hindering conclusions about the disease epidemiology. This study offers an insight into DED epidemiology in the UK u...

The Association between Decreased Choriocapillary Flow and Electroretinogram Impairments in Patients with Diabetes.

Apr 03, 2023

To evaluate the association between choriocapillary flow (CCF) and electroretinogram (ERG) in patients with diabetes.This was a cross-sectional study. Patients with type 2 diabetes and healthy control...

Metabolomic analysis of aqueous humor reveals potential metabolite biomarkers for differential detection of macular edema.

Apr 03, 2023

Macular edema (ME) is a major complication of retinal disease with multiple mechanisms involved in its development. This study aimed to investigate the metabolite profile of aqueous humor (AH) in pati...

A Scoping Review of Patients' Barriers to Eye Care for Glaucoma and Keratitis.

Apr 03, 2023

In this scoping review, we examine underlying causes of loss to follow-up for chronic (glaucoma) and acute (corneal ulcers) eye conditions using the Penchansky and Thomas access to care framework. We ...

Systematic analysis of levels of evidence supporting American Academy of Ophthalmology Preferred Practice Pattern guidelines, 2012-2021.

Apr 03, 2023

Despite the increased emphasis on evidence-based medicine, the current state of evidence behind ophthalmology clinical practice guidelines is unknown. The purpose of this systematic analysis was to un...

Retinal Glial Cell Activation Contributes to Glaucoma-Induced Ganglion Cell Degeneration

Mar 31, 2023

The following is a summary of the “Activation of retinal glial cells contributes to the degeneration of ganglion cells in experimental glaucoma,” published in the March 2023 issue of Progress in r...

Gut Microbiome's Impact on Eye Health

Mar 30, 2023

The following is a summary of the “Role of the gut microbiome in eye diseases,” published in the January 2023 issue of Progress in retinal and eye research by Burri, et al. The intestinal m...

Measuring Success in Voretigene Neparvovec Therapy

Mar 29, 2023

The following is a summary of the “Therapy with voretigene neparvovec. How to measure success?,” published in the January 2023 issue of Progress in retinal and eye research by Stingl, et al. ...

Retinal TRP Channels: Regulators of Multimodal Integration and Retinal Homeostasis

Mar 28, 2023

The following is a summary of the “Retinal TRP channels: Cell-type-specific regulators of retinal homeostasis and multimodal integration,” published in the January 2023 issue of Progress in retina...

Exploring Macular Neovascularization and Non-Exudative Choroidal

Mar 27, 2023

The following is a summary of the “Towards a better understanding of non-exudative choroidal and macular neovascularization,” published in the Jan 2023 issue of Progress in retinal and eye researc...

Changes in choroidal thickness in myopic children with 0.01% atropine: evidence from a 12-month follow-up.

Mar 27, 2023

To investigate the changes of low-dose atropine (0.01%) on the choroidal thickness (ChT) of young children with low myopia.A total of 25 eyes of 25 low myopic children were included. All subjects were...

Inhibitory effect of miR-138-5p on choroidal fibrosis in lens-induced myopia guinea pigs via suppressing the HIF-1α signaling pathway.

Mar 27, 2023

Myopia is one of the most common eye diseases in children and adolescents worldwide. Currently, there is no effective treatment in clinical practice. Ocular tissue fibrosis is involved in the developm...

Most Common Ophthalmic Diagnoses in Eye Emergency Departments: A Multicenter Study.

Mar 27, 2023

To characterize the most common ophthalmic conditions seen in the emergency department (ED) DESIGN: Cross-sectional study METHODS: Multicenter study of 64988 patients who visited the Bascom Palmer Eye...

Vision-related quality of life after surgery for vitreoretinal disorders in a Mexican population: an observational study.

Mar 27, 2023

Visual-related quality of life in retinal diseases has not been explored in the Mexican population, so the study aims to identify it in patients undergoing surgery due to advanced diabetic retinopathy...

Altered functional connectivity between the default mode network in diabetic retinopathy patients.

Mar 27, 2023

Previous studies have demonstrated that diabetic retinopathy is associated with cognitive impairment. This study aimed to investigate the intrinsic functional connectivity pattern within the default m...

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