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Ophthalmology General

Visual Restoration Through Optogenetics

Jan 20, 2023

The following is the summary of “Optogenetics for visual restoration: From proof of principle to translational challenges” published in November 2022 issue of Retinal and Eye by  Lindner, et al. ...

A novel biosensing platform for detection of glaucoma biomarker GDF15 via an integrated BLI-ELASA strategy.

Jan 16, 2023

Glaucoma is a leading cause of irreversible blindness worldwide. Early discovery and prioritized intervention significantly impact its prognosis. Precise monitoring of the biomarker GDF15 contributes ...

Photoreceptor laminin drives differentiation of human pluripotent stem cells to photoreceptor progenitors that partially restore retina function.

Jan 16, 2023

Blindness caused by advanced stages of inherited retinal diseases and age-related macular degeneration are characterized by photoreceptor loss. Cell therapy involving replacement with functional photo...

Influence of location, season and time of day on the spectral composition of ambient light: Investigation for application in myopia.

Jan 16, 2023

Given the possible role of spectral composition of light and myopia, this study aimed at investigating the variation in the spectral composition of ambient light in different (a) outdoor/indoor locati...

Preoperative geometric parameters predict the outcome of lamellar keratoscleroplasty in patients with limbal dermoids.

Jan 16, 2023

To find preoperative simple geometric parameters to predict the outcome of lamellar keratoscleroplasty in patients with corneal limbal dermoids.We retrospectively analyzed the data of 30 patients with...

Evaluation of Dry Eye Severity and Ocular Surface Inflammation in Patients with Pemphigus and Pemphigoid.

Jan 16, 2023

To evaluate ocular surface involvement, tear cytokine levels, and histopathological changes in pemphigus and pemphigoid patients.A total of 22 patients (15 pemphigus and 7 pemphigoids) and 21 non-dise...

The protective effect of luteolin on the depression-related dry eye disorder through Sirt1/NF-κB/NLRP3 pathway.

Jan 16, 2023

Luteolin has been reported to exhibit therapeutic effect on depressive-like behaviors in mice. Nevertheless, the therapeutic effect of luteolin on the depression-related dry eye disorder remains incon...

25-hydroxyvitamin D3 inhibits oxidative stress and ferroptosis in retinal microvascular endothelial cells induced by high glucose through down-regulation of miR-93.

Jan 16, 2023

The decrease of vitamin D plays a critical role in diabetes mellitus (DM)-induced oxidative stress and vascular endothelial injury. Therefore, we investigated the effect and mechanism of 25-hydroxyvit...

HIF-1α accumulation in response to transient hypoglycemia may worsen diabetic eye disease.

Jan 16, 2023

Tight glycemic control (TGC), the cornerstone of diabetic management, reduces the incidence and progression of diabetic microvascular disease. However, TGC can also lead to transient episodes of hypog...

An Association between Large Optic Cupping and Total and Regional Brain Volume: The Women's Health Initiative.

Jan 16, 2023

To investigate the relationships between optic nerve cupping and total and regional brain volumes.Secondary analysis of randomized clinical trial data.Women, aged 65 to 79, without glaucoma with cup-t...

The effect of citicoline oral solution on quality of life in patients with glaucoma: the results of an international, multicenter, randomized, placebo-controlled cross-over trial.

Jan 16, 2023

This study aims to evaluate whether the use of citicoline oral solution could improve quality of life in patients with chronic open-angle glaucoma (OAG).Randomized, double-masked, placebo-controlled, ...

Association Between Preresidency Peer-reviewed Publications and Future Academic Productivity or Career Choice Among Ophthalmology Residency Applicants.

Jan 16, 2023

Ophthalmology-residency selection committees require robust metrics to review applicants. Participation in research activities is a core component of the application process for its perceived associat...

A Phone Triage System for Patients Calling with Symptoms of a Posterior Vitreous Detachment.

Jan 16, 2023

Develop a simple phone questionnaire, without physical exam input, that predicts which patients calling with symptoms of a posterior vitreous detachment (PVD) have a retinal tear or rhegmatogenous ret...

Analysis of Non-vasogenic Cystoid Maculopathies (NVCM)

Jan 12, 2023

The following is the summary of “Non-vasogenic cystoid maculopathies” published in the November 2022 issue of Progress in retinal and eye research by Gaudric, et al. Non-vasogenic cystoid m...

Early Retinal Development: Cell Destiny Choices, Signalling, and Transcription Factors

Jan 12, 2023

The following is the summary of “Cell fate decisions, transcription factors and signaling during early retinal development” published in November 2022 issue of Retinal and eye research by Diacou, ...

Using a Paradigm Shift to Repair Retinal Detachments

Jan 12, 2023

The following is the summary of “A paradigm shift in retinal detachment repair: The concept of integrity” published in November 2022 issue of Retinal and Eye by Muni, et al. Rhegmatogenous ...

In Vitro Evaluation of α-amylase and α-glucosidase Inhibition of 2,3-Epoxyprocyanidin C1 and Other Constituents from Poir.

Jan 09, 2023

Diabetes mellitus is a metabolic disorder which is one of the leading causes of mortality and morbidities in elderly humans. Chronic diabetes can lead to kidney failure, blindness, limb amputation, he...

A Deep-Learning-Based Collaborative Edge-Cloud Telemedicine System for Retinopathy of Prematurity.

Jan 09, 2023

Retinopathy of prematurity is an ophthalmic disease with a very high blindness rate. With its increasing incidence year by year, its timely diagnosis and treatment are of great significance. Due to th...

Impact of peripapillary staphylomas on the vascular and structural characteristics in myopic eyes: a propensity score matching analysis.

Jan 09, 2023

To apply propensity score matching to evaluate the impact of peripapillary staphylomas (PPS) on vascular and structural characteristics in the myopic eyes.This was a prospective, cross-sectional study...

Nasopharyngeal Carcinoma and Its Effect on Dry Eye Disease: A Nationwide Cohort Study.

Jan 09, 2023

The aim of the current study was to investigate the relationship between nasopharyngeal carcinoma (NPC) and dry eye disease (DED) using the National Health Insurance Research Database (NHIRD) of Taiwa...

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