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Ophthalmology General

How Can Artificial Intelligence Be Implemented Effectively in Diabetic Retinopathy Screening in Japan?

Feb 26, 2024

Diabetic retinopathy (DR) is a major microvascular complication of diabetes, affecting a substantial portion of diabetic patients worldwide. Timely intervention is pivotal in mitigating the risk of bl...

Ultra-Wide-Field Optical Coherence Tomography and Gaussian Curvature to Assess Macular and Paravascular Retinoschisis in High Myopia.

Feb 26, 2024

To evaluate the severity and related factors of macular retinoschisis (MRS) and paravascular retinoschisis (PVRS) in high myopia (HM) using ultra-wide-field optical coherence tomography (UWF-OCT) and ...

Effect of capsular tension ring on the refractive outcomes of patients with extreme high axial myopia after phacoemulsification.

Feb 26, 2024

The aim of the study is to evaluate the effect of capsular tension ring (CTR) implantation following cataract surgery on the refractive outcomes of patients with extreme high axial myopia.Sixty eyes (...

Enhancing Ocular Surface in Dry Eye Disease Patients: A Clinical Evaluation of a Topical Formulation Containing Sesquiterpene Lactone Helenalin.

Feb 26, 2024

The aim of this work was to assess the tolerability, safety, and efficacy of an ophthalmic topical formulation containing helenalin from and hyaluronic acid 0.4% (HA) in patients with mild-to-moderat...

Efficacy and Safety of Artificial Tears Containing Lipidure and Hypromellose for the Treatment of Moderate Dry Eye Disease in Contact Lens Wearers.

Feb 26, 2024

: Dry eye disease (DED) affects 5-50% of the global population and deeply influences everyday life activities. This study compared the efficacy, tolerability, and safety of novel Respilac artificial t...

Ocular microvascular alteration in patients with myocardial infarction-a new OCTA study.

Feb 26, 2024

Myocardial infarction is defined as a sudden decrease or interruption in blood flow to the coronary arteries, causing ischemic necrosis of the corresponding cardiomyocytes. It is unclear whether syste...

Macula vs periphery in diabetic retinopathy: OCT-angiography and ultrawide field fluorescein angiography imaging of retinal non perfusion.

Feb 26, 2024

To investigate the association between peripheral non-perfusion index (NPI) on ultrawide-field fluorescein angiography (UWF-FA) and quantitative OCT-Angiography (OCT-A) metrics in the macula.In total,...

A comparative analysis of IOP measurement accuracy with reused iCare probes.

Feb 26, 2024

To assess the accuracy of reused iCare probes after disinfection with 70% isopropyl alcohol and ethylene glycol compared to new iCare probes and Goldmann Applanation Tonometry (GAT).Prospective compar...

Effectiveness and safety of XEN63 in patients with primary-open-angle glaucoma.

Feb 26, 2024

This paper evaluates the effectiveness and safety of XEN63 stent, either standalone or in combination with phacoemulsification, in patients with primary open-angle glaucoma (POAG). Eighty eyes from 80...

Assessment of a Large Language Model's Responses to Questions and Cases About Glaucoma and Retina Management.

Feb 26, 2024

Large language models (LLMs) are revolutionizing medical diagnosis and treatment, offering unprecedented accuracy and ease surpassing conventional search engines. Their integration into medical assist...

Comparison of early changes in tear film protein profiles after small incision lenticule extraction (SMILE) and femtosecond LASIK (FS-LASIK) surgery.

Feb 19, 2024

Small incision lenticule extraction (SMILE) and femtosecond laser-assisted in situ keratomileusis (LASIK) are widely used surgical methods to correct myopia with comparable efficacy, predictability, a...

Evaluation of Dry Eye Severity and Ocular Surface Inflammation in Patients with Autoimmune Rheumatic Diseases.

Feb 19, 2024

To evaluate dry eye severity and ocular surface inflammation in autoimmune rheumatic diseases (ARDs).Seventy-nine patients with ARDs were enrolled, including 26 patients with rheumatoid arthritis (RA)...

Resilient back-propagation machine learning-based classification on fundus images for retinal microaneurysm detection.

Feb 19, 2024

The timely diagnosis of medical conditions, particularly diabetic retinopathy, relies on the identification of retinal microaneurysms. However, the commonly used retinography method poses a challenge ...

Epiretinal membrane development after Ex-Press glaucoma filtration device implant: 2-year results of a case control study.

Feb 19, 2024

The most common retinal complications after glaucoma surgery are choroidal detachment, hypotony maculopathy, malignant glaucoma, vitreous hemorrhage, endophthalmitis and retinal detachment. However, i...

Infectious eye disease in the 21st century-an overview.

Feb 19, 2024

Infectious diseases affecting the eye often cause unilateral or asymmetric visual loss in children and people of working age. This group of conditions includes viral, bacterial, fungal and parasitic d...

The role of transforming growth factor beta in myopia development.

Feb 12, 2024

Myopia is widely recognized as an epidemic. Studies have found a link between Transforming Growth Factor-beta (TGF-β) and myopia, but the specific molecular mechanisms are not fully understood. In th...

A novel variant of DNM1L expanding the clinical phenotypic spectrum: a case report and literature review.

Feb 12, 2024

Mitochondrial diseases are heterogeneous in terms of clinical manifestations and genetic characteristics. The dynamin 1-like gene (DNM1L) encodes dynamin-related protein 1 (DRP1), a member of the GTPa...

A Systematic Review of Tear Vascular Endothelial Growth Factor and External Eye Diseases.

Feb 12, 2024

We aim to summarize the current evidence of Vascular endothelial growth factors (VEGF)s in external eye diseases and determine whether serum and plasma VEGF levels are associated with tear and ocular ...

Two-Photon and Multiphoton Microscopy in Anterior Segment Diseases of the Eye.

Feb 12, 2024

Two-photon excitation microscopy (TPM) and multiphoton fluorescence microscopy (MPM) are advanced forms of intravital high-resolution functional microscopy techniques that allow for the imaging of dyn...

PFKFB3 in neovascular eye disease: unraveling mechanisms and exploring therapeutic strategies.

Feb 12, 2024

Neovascular eye disease is characterized by pathological neovascularization, with clinical manifestations such as intraocular exudation, bleeding, and scar formation, ultimately leading to blindness i...

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