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Ophthalmology General

Epiretinal membrane development after Ex-Press glaucoma filtration device implant: 2-year results of a case control study.

Feb 19, 2024

The most common retinal complications after glaucoma surgery are choroidal detachment, hypotony maculopathy, malignant glaucoma, vitreous hemorrhage, endophthalmitis and retinal detachment. However, i...

Infectious eye disease in the 21st century-an overview.

Feb 19, 2024

Infectious diseases affecting the eye often cause unilateral or asymmetric visual loss in children and people of working age. This group of conditions includes viral, bacterial, fungal and parasitic d...

The role of transforming growth factor beta in myopia development.

Feb 12, 2024

Myopia is widely recognized as an epidemic. Studies have found a link between Transforming Growth Factor-beta (TGF-β) and myopia, but the specific molecular mechanisms are not fully understood. In th...

A novel variant of DNM1L expanding the clinical phenotypic spectrum: a case report and literature review.

Feb 12, 2024

Mitochondrial diseases are heterogeneous in terms of clinical manifestations and genetic characteristics. The dynamin 1-like gene (DNM1L) encodes dynamin-related protein 1 (DRP1), a member of the GTPa...

A Systematic Review of Tear Vascular Endothelial Growth Factor and External Eye Diseases.

Feb 12, 2024

We aim to summarize the current evidence of Vascular endothelial growth factors (VEGF)s in external eye diseases and determine whether serum and plasma VEGF levels are associated with tear and ocular ...

Two-Photon and Multiphoton Microscopy in Anterior Segment Diseases of the Eye.

Feb 12, 2024

Two-photon excitation microscopy (TPM) and multiphoton fluorescence microscopy (MPM) are advanced forms of intravital high-resolution functional microscopy techniques that allow for the imaging of dyn...

PFKFB3 in neovascular eye disease: unraveling mechanisms and exploring therapeutic strategies.

Feb 12, 2024

Neovascular eye disease is characterized by pathological neovascularization, with clinical manifestations such as intraocular exudation, bleeding, and scar formation, ultimately leading to blindness i...

Effect of non-overlapping visual field defects on vision related quality of life in glaucoma.

Feb 12, 2024

Glaucoma patients may be considered to have normal vision as long as each point of visual space is perceived by at least one eye, that is, with an intact binocular visual field. We aimed to investigat...

Geometric transformation adaptive optics (GTAO) for volumetric deep brain imaging through gradient-index lenses.

Feb 05, 2024

The advance of genetic function indicators has enabled the observation of neuronal activities at single-cell resolutions. A major challenge for the applications on mammalian brains is the limited opti...

Extending the Scope of Conceptual Density Functional Theory with Second Order Analytical Methodologies.

Feb 05, 2024

In the context of the growing impact of conceptual density functional theory (DFT) as one of the most successful chemical reactivity theories, response functions up to second order have now been widel...

Characterizing the Robustness of Distinct Clinical Assessments in Identifying Dry Eye Condition of Animal Models.

Feb 05, 2024

The study aims to characterize the robustness of distinct clinical assessments in identifying the underlying conditions of dry eye disease (DED), with a specific emphasis on the involvement of conjunc...

Association between systemic medication use and severity of dry eye signs and symptoms in the DRy eye assessment and management (DREAM) study.

Feb 05, 2024

Some systemic medications are reported to be associated with dry eye disease (DED), yet their associations with the severity of DED signs and symptoms are not well studied. To evaluate these associati...

Present and future screening programs for diabetic retinopathy: a narrative review.

Feb 05, 2024

Diabetes is a prevalent global concern, with an estimated 12% of the global adult population affected by 2045. Diabetic retinopathy (DR), a sight-threatening complication, has spurred diverse screenin...

Deciphering Immune-Related Gene Signatures in Diabetic Retinopathy: Insights from In Silico Analysis and In vitro Experiment.

Feb 05, 2024

Diabetes retinopathy (DR) is one of the most common microvascular consequences of diabetes, and the economic burden is increasing. Our aim is to decipher the relevant mechanisms of immune-related gene...

Fabrication of carboxymethyl cellulose-based thermo-sensitive hydrogels and inhibition of corneal neovascularization.

Feb 05, 2024

Corneal neovascularization (CNV) is a common multifactorial sequela of anterior corneal segment inflammation, which could lead to visual impairment and even blindness. The main treatments available ar...

Validation of WINROP algorithm as screening tool of retinopathy of prematurity among Egyptian preterm neonates.

Feb 05, 2024

Retinopathy of prematurity (ROP) is a leading cause of preventable childhood blindness worldwide. Proper screening for ROP can prevent loss of vision. WINROP (weight, insulin-like growth factor 1, neo...

Amblyopia Care Trends Following Widespread Photoscreener Adoption.

Feb 05, 2024

Amblyopia can result in permanent vision loss if not properly treated before age 7 years. In 2017, the US Preventive Services Task Force recommended that vision screening should occur at least once in...

The incidence, clinical features, and management of essential infantile esotropia in the United Kingdom. A British Ophthalmology Surveillance Unit (BOSU) study.

Feb 05, 2024

A national study was undertaken through the British ophthalmology surveillance unit (BOSU) to determine the incidence, presenting features and management of essential infantile esotropia (EIE) in the ...

Sterile granulomatous panuveitis in dogs in the United Kingdom: A review of 33 cases.

Jan 29, 2024

To describe the clinical and histopathological features of a sterile granulomatous panuveitis syndrome in 33 dogs that underwent enucleation and ocular histopathology.Retrospective review of the medic...

Nutraceutical potential of olive pomace: insights from cell-based and clinical studies.

Jan 29, 2024

Olive oil production yields a substantial volume of by-products, constituting up to 80% of the processed fruits. The olive pomace by-product represents a residue of significant interest due to the div...

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