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Ophthalmology General

Segmentation-Assisted Fully Convolutional Neural Network Enhances Deep Learning Performance to Identify Proliferative Diabetic Retinopathy.

Jan 09, 2023

With the progression of diabetic retinopathy (DR) from the non-proliferative (NPDR) to proliferative (PDR) stage, the possibility of vision impairment increases significantly. Therefore, it is clinica...

3D-printed long-acting 5-fluorouracil implant to prevent conjunctival fibrosis in glaucoma.

Jan 09, 2023

To develop a sustained release 5-fluorouracil (5-FU) implant by three-dimensional (3D) printing to effectively prevent conjunctival fibrosis after glaucoma surgery.3D-printed implants composed of poly...

Analysis of Optogenetics Therapy for Vision Restoration

Jan 06, 2023

The following is the summary of “Optogenetics for visual restoration: From proof of principle to translational challenges” published in November 2022 issue of Retinal and Eye by  Lindner, et al. ...

Using a Paradigm Shift to Repair Retinal Detachments

Jan 06, 2023

The following is the summary of “A paradigm shift in retinal detachment repair: The concept of integrity” published in November 2022 issue of progress in Retinal and Eye by Muni, et al. Rhe...

Prevalence of myopia and associated risk factors among key schools in Xi'an, China.

Jan 02, 2023

The aim of this study is to investigate the prevalence of myopia and high myopia and the associated risk factors in key schools in Xi'an, China.This cross-sectional study started in September 2021 and...

Changes in Vector Astigmatism After Superotemporal Versus Temporal Clear Corneal Incision Cataract Surgery.

Jan 02, 2023

To investigate vector and refractive astigmatism changes after superotemporal versus temporal clear corneal incision cataract surgery.Patients were diagnosed with age-related cataract with corneal ast...

A phase 2a, double-masked, randomized, vehicle-controlled trial of VVN001 in subjects with dry eye disease.

Jan 02, 2023

Evaluate the initial ocular safety and tolerability and efficacy of VVN001 Ophthalmic Solution (VVN001), a small-molecule antagonist of lymphocyte function-associated antigen-1 (LFA-1), in subjects wi...

Pathological changes in a model of retinal cholesterol dyshomeostasis and their mitigation by pharmacologic treatment.

Jan 02, 2023

CYP46A1 is a CNS-specific enzyme, which eliminates cholesterol from the brain and retina by metabolism to 24-hydroxycholesterol, thus contributing to cholesterol homeostasis in both organs. 2-Hydroxyp...

Vitreous humor proteome: unraveling the molecular mechanisms underlying proliferative and neovascular vitreoretinal diseases.

Jan 02, 2023

Proliferative diabetic retinopathy (PDR), proliferative vitreoretinopathy (PVR), and neovascular age-related macular degeneration (nAMD) are among the leading causes of blindness. Due to the multifact...

Reverse engineering for reconstructing baseline features of dry age-related macular degeneration in optical coherence tomography.

Jan 02, 2023

Age-related macular degeneration (AMD) is the most widespread cause of blindness and the identification of baseline AMD features or biomarkers is critical for early intervention. Optical coherence tom...

The UCI EyeMobile Preschool Vision Screening Program: Refractive Error and Amblyopia Results from the 2019-2020 School Year.

Jan 02, 2023

To introduce the University of California Irvine (UCI) EyeMobile for Children preschool vision screening program and describe the ophthalmic examination results of children who failed screening with t...

Choroidal melanoma tumor profile and treatment pattern for newly diagnosed patients at a reference public hospital in Sao Paulo, Brazil.

Jan 02, 2023

Choroid, ciliary body, and iris melanomas are often grouped as uveal melanoma, the most common intraocular primary malignancy. The purpose of the current study was to analyze the tumor profile of newl...

The Impact of Latanoprost on CVI in Ocular and Glaucoma Hypertension

Dec 30, 2022

The following is the summary of “Effect of Latanoprost on Choroidal Vascularity Index in Glaucoma and Ocular Hypertension” published in the December 2022 issue of Glaucoma by Cakir, et al. ...

Using a PreserFlo MicroShunt Device After Needling to Relieve Blood Reflux

Dec 30, 2022

The following is the summary of “Blood Reflux Through a PreserFlo MicroShunt Device After Needling” published in the December 2022 issue of Glaucoma by Cassottana, et al. The purpose of thi...

Trabeculotomy Failure Risk Factors in Primary Congenital Glaucoma

Dec 30, 2022

The following is the summary of “Risk Factors for Trabeculotomy Failure in Primary Congenital Glaucoma” published in the December 2022 issue of Glaucoma by Aktas, et al. Baseline corneal di...

NPDS and XEN Gel Stent Effectiveness and Safety

Dec 23, 2022

The following is the summary of “One-Year Outcomes of Standalone XEN Gel Stent Versus Non Penetrating Deep Sclerectomy” published in the December 2022 issue of Glaucoma by Touboul, et al. T...

OCT Methods for Glaucoma Detection in Myopic Eyes: Structural and Vascular Evaluation

Dec 23, 2022

The following is the summary of “Glaucoma Detection in Myopic Eyes: Structural and Vascular Assessment by Optic Coherence Tomography Methods” published in the December 2022 issue of Glaucoma by Ca...

Cushing's Disease Patients are More Likely to Have Ocular Hypertension

Dec 23, 2022

The following is the summary of “Increased Risk of Ocular Hypertension in Patients With Cushing’s Disease” published in the December 2022 issue of Glaucoma by Ma, et al. Ocular hypertensi...

Limited bandwidth short-wavelength light produces slowly-developing myopia in tree shrews similar to human juvenile-onset myopia.

Dec 19, 2022

During postnatal development, an emmetropization feedback mechanism uses visual cues to modulate the axial growth of eyes so that, with maturation, images of distant objects are in focus on the retina...

Infectious keratitis: an update on the prevalence, risk factors, culture results, clinical features, visual outcomes, and therapeutic strategies of infectious keratitis.

Dec 19, 2022

This study aimed to assess the prevalence, risk factors, culture results, clinical features, visual outcomes, and therapeutic strategies of infectious keratitis after surface ablation (PRK).This singl...

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