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Ophthalmology General

A phase 2a, double-masked, randomized, vehicle-controlled trial of VVN001 in subjects with dry eye disease.

Jan 02, 2023

Evaluate the initial ocular safety and tolerability and efficacy of VVN001 Ophthalmic Solution (VVN001), a small-molecule antagonist of lymphocyte function-associated antigen-1 (LFA-1), in subjects wi...

Pathological changes in a model of retinal cholesterol dyshomeostasis and their mitigation by pharmacologic treatment.

Jan 02, 2023

CYP46A1 is a CNS-specific enzyme, which eliminates cholesterol from the brain and retina by metabolism to 24-hydroxycholesterol, thus contributing to cholesterol homeostasis in both organs. 2-Hydroxyp...

Vitreous humor proteome: unraveling the molecular mechanisms underlying proliferative and neovascular vitreoretinal diseases.

Jan 02, 2023

Proliferative diabetic retinopathy (PDR), proliferative vitreoretinopathy (PVR), and neovascular age-related macular degeneration (nAMD) are among the leading causes of blindness. Due to the multifact...

Reverse engineering for reconstructing baseline features of dry age-related macular degeneration in optical coherence tomography.

Jan 02, 2023

Age-related macular degeneration (AMD) is the most widespread cause of blindness and the identification of baseline AMD features or biomarkers is critical for early intervention. Optical coherence tom...

The UCI EyeMobile Preschool Vision Screening Program: Refractive Error and Amblyopia Results from the 2019-2020 School Year.

Jan 02, 2023

To introduce the University of California Irvine (UCI) EyeMobile for Children preschool vision screening program and describe the ophthalmic examination results of children who failed screening with t...

Choroidal melanoma tumor profile and treatment pattern for newly diagnosed patients at a reference public hospital in Sao Paulo, Brazil.

Jan 02, 2023

Choroid, ciliary body, and iris melanomas are often grouped as uveal melanoma, the most common intraocular primary malignancy. The purpose of the current study was to analyze the tumor profile of newl...

The Impact of Latanoprost on CVI in Ocular and Glaucoma Hypertension

Dec 30, 2022

The following is the summary of “Effect of Latanoprost on Choroidal Vascularity Index in Glaucoma and Ocular Hypertension” published in the December 2022 issue of Glaucoma by Cakir, et al. ...

Using a PreserFlo MicroShunt Device After Needling to Relieve Blood Reflux

Dec 30, 2022

The following is the summary of “Blood Reflux Through a PreserFlo MicroShunt Device After Needling” published in the December 2022 issue of Glaucoma by Cassottana, et al. The purpose of thi...

Trabeculotomy Failure Risk Factors in Primary Congenital Glaucoma

Dec 30, 2022

The following is the summary of “Risk Factors for Trabeculotomy Failure in Primary Congenital Glaucoma” published in the December 2022 issue of Glaucoma by Aktas, et al. Baseline corneal di...

NPDS and XEN Gel Stent Effectiveness and Safety

Dec 23, 2022

The following is the summary of “One-Year Outcomes of Standalone XEN Gel Stent Versus Non Penetrating Deep Sclerectomy” published in the December 2022 issue of Glaucoma by Touboul, et al. T...

OCT Methods for Glaucoma Detection in Myopic Eyes: Structural and Vascular Evaluation

Dec 23, 2022

The following is the summary of “Glaucoma Detection in Myopic Eyes: Structural and Vascular Assessment by Optic Coherence Tomography Methods” published in the December 2022 issue of Glaucoma by Ca...

Cushing's Disease Patients are More Likely to Have Ocular Hypertension

Dec 23, 2022

The following is the summary of “Increased Risk of Ocular Hypertension in Patients With Cushing’s Disease” published in the December 2022 issue of Glaucoma by Ma, et al. Ocular hypertensi...

Limited bandwidth short-wavelength light produces slowly-developing myopia in tree shrews similar to human juvenile-onset myopia.

Dec 19, 2022

During postnatal development, an emmetropization feedback mechanism uses visual cues to modulate the axial growth of eyes so that, with maturation, images of distant objects are in focus on the retina...

Infectious keratitis: an update on the prevalence, risk factors, culture results, clinical features, visual outcomes, and therapeutic strategies of infectious keratitis.

Dec 19, 2022

This study aimed to assess the prevalence, risk factors, culture results, clinical features, visual outcomes, and therapeutic strategies of infectious keratitis after surface ablation (PRK).This singl...

The efficacy of ocular surface assessment approaches in evaluating dry eye treatment with artificial tears.

Dec 19, 2022

This study evaluates the effectiveness of objective techniques in assessing dry eye disease (DED) treatment compared with the subjective assessment commonly used in clinical practice. Thirty subjects ...

Quantification of risk factors for diabetic retinopathy progression.

Dec 19, 2022

To determine the importance of blood sugar control, blood pressure, and other key systemic factors on the risk of progression from no retinopathy to various stages of diabetic retinopathy.Restrospecti...

An efficient registration-based approach for retinal blood vessel segmentation using generalized Pareto and fatigue pdf.

Dec 19, 2022

Segmentation of Retinal Blood Vessel (RBV) extraction in the retina images and Registration of segmented RBV structure is implemented to identify changes in vessel structure by ophthalmologists in dia...

Optical coherence tomography imaging biomarkers associated with neovascular age-related macular degeneration: a systematic review.

Dec 19, 2022

The aim of this systematic literature review is twofold, (1) detail the impact of retinal biomarkers identifiable via optical coherence tomography (OCT) on disease progression and response to treatmen...

Corneal Hysteresis for the Diagnosis of Glaucoma and Assessment of Progression Risk: A Report by the American Academy of Ophthalmology.

Dec 19, 2022

To review the current published literature on the utility of corneal hysteresis (CH) to assist the clinician in the diagnosis of glaucoma or in the assessment of risk for disease progression in existi...

Transformational Apparent Motion Based on High-level Shape Representations: Endogenous Attention

Dec 12, 2022

The following is a summary of "Endogenous attention biases transformational apparent motion based on high-level shape representations" published in the November 2022 issue of Vision by Saleki, et al. ...

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