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Ophthalmology General

Adversarial learning-based domain adaptation algorithm for intracranial artery stenosis detection on multi-source datasets.

Jan 29, 2024

Intracranial arterial stenosis (ICAS) is characterized by the pathological narrowing or occlusion of the inner lumen of intracranial blood vessels. However, the retina can indirectly react to cerebrov...

Lipid Mediators in Glaucoma: Unraveling Their Diverse Roles and Untapped Therapeutic Potential.

Jan 29, 2024

Glaucoma is a complex neurodegenerative disease characterized by optic nerve damage and visual field loss and remains a leading cause of irreversible blindness. Elevated intraocular pressure (IOP) is ...

Managing the apparently blind child presenting in the first year of life: A review.

Jan 22, 2024

Severe vision impairment and blindness in childhood have a significant health burden on the child, family and society. This review article seeks to provide a structured framework for managing the appa...

A multi-cohort genome-wide association study in African ancestry individuals reveals risk loci for primary open-angle glaucoma.

Jan 22, 2024

Primary open-angle glaucoma (POAG), the leading cause of irreversible blindness worldwide, disproportionately affects individuals of African ancestry. We conducted a genome-wide association study (GWA...

Open Fundus Photograph Dataset with Pathologic Myopia Recognition and Anatomical Structure Annotation.

Jan 22, 2024

Pathologic myopia (PM) is a common blinding retinal degeneration suffered by highly myopic population. Early screening of this condition can reduce the damage caused by the associated fundus lesions a...

Relationship between dynamic visual acuity and static visual acuity, refractive error, and binocular vision in elite soccer players.

Jan 22, 2024

In many sports, dynamic visual acuity is used. In order to improve dynamic visual acuity, it is important to understand the aspects of the visual system that can cause compromise.To investigate the pa...

ER-1 deficiency induces inflammation and lipid deposition in meibomian gland and lacrimal gland.

Jan 22, 2024

To investigated the role of estrogen receptor-1 (ER-1) in maintaining homeostasis in ocular surface.ER-1-knockout (ER-1KO) mice were studied at 4 months of age. The ocular surface was examined using a...

Social Determinants of Dry Eye in the United States: A Systematic Review.

Jan 22, 2024

Goal To conduct a systematic review to summarize current evidence on associations between social determinants of health (SDOH) indicators and dry eye in the U.S. Systematic review We followed...

Salidroside protects RGC from pyroptosis in diabetes-induced retinopathy associated with NLRP3, NFEZL2 and NGKB1, revealed by network pharmacology analysis and experimental validation.

Jan 22, 2024

To investigate the effect of salidroside (SAL) in protecting retinal ganglion cell (RGC) from pyroptosis and explore associated molecular network mechanism in diabetic retinapathy (DR) rats.HE, Nissl ...

Comparison between 24-2 ZEST and 24-2 ZEST FAST Strategies in Glaucoma and Ocular Hypertension using a Fundus Perimeter.

Jan 22, 2024

Using a Compass (CMP, Centervue, Padova, Italy) fundus perimeter, ZEST FAST strategy showed a significant reduction in examination time compared to ZEST, with good agreement in the quantification of p...

Deep Learning Model Successfully Identifies Clinically Significant Glaucoma Progression in Macular OCT Imaging Studies

Jan 22, 2024

To use macular OCT imaging to predict future and detect concurrent visual field progression, respectively, using deep learning. Retrospective cohort study. A pre-training dataset was comprised of 7,...

Reliability and accuracy of artificial intelligence ChatGPT in providing information on ophthalmic diseases and management to patients.

Jan 22, 2024

To assess the accuracy of ophthalmic information provided by an artificial intelligence chatbot (ChatGPT).Five diseases from 8 subspecialties of Ophthalmology were assessed by ChatGPT version 3.5. Thr...

Causal relationships between Gut microbiota and primary open-angle Glaucoma: A Mendelian randomization and mediation analysis of Glaucoma endophenotypes.

Jan 15, 2024

Primary open-angle glaucoma (POAG) is a widespread condition responsible for irreversible blindness, and its prevalence is expected to increase substantially in the coming decades. Despite its signifi...

Outcome of combined cataract surgery and iris prosthesis implantation in iris melanoma patients previously treated with iridocyclectomy: A national retrospective non-comparative case series.

Jan 15, 2024

To examine complications, visual outcomes, photic patient-reported symptoms, corneal morphology, IOL tilt, and intraocular pressure after implantation of an intraocular lens (IOL) and iris prosthesis ...

Biodegradable microneedle acupuncture has equivalent efficacy to traditional intradermal acupuncture for dry eye disease: A pilot single-blinded, randomized controlled trial.

Jan 15, 2024

Dry eye disease (DED) is a common ocular disorder in which the tear film cannot maintain homeostasis. Acupuncture has been used to treat DED in Korean medicine. Particularly, intradermal acupuncture (...

The Influence of Lid-Parallel Conjunctival Folds and Conjunctivochalasis on Dry Eye Symptoms with and Without Contact Lens Wear: A Review of the Literature.

Jan 15, 2024

Lid-parallel conjunctival folds (LIPCOF) and conjunctivochalasis (CCH) are similar conditions that seem to be related to dry eye severity. In addition, there is a lack of studies on the topic of LIPCO...

Association between serum heavy metal levels and diabetic retinopathy in NHANES 2011-2020.

Jan 15, 2024

The present study utilized the National Health and Nutrition Examination Survey (NHANES) database to examine the relationship between serum levels of heavy metals and Diabetic retinopathy (DR) in indi...

Gene knockout of RNA binding motif 5 in the brain alters RIMS2 protein homeostasis in the cerebellum and Hippocampus and exacerbates behavioral deficits after a TBI in mice.

Jan 15, 2024

RNA binding motif 5 (RBM5) is a tumor suppressor in cancer but its role in the brain is unclear. We used conditional gene knockout (KO) mice to test if RBM5 inhibition in the brain affects chronic cor...

Incidence of Sympathetic Ophthalmia Following Intraocular Surgery: A Systematic Review and Meta-Analysis.

Jan 15, 2024

Sympathetic ophthalmia (SO) is a rare bilateral granulomatous panuveitis that can present after trauma or intraocular surgery (IOS). The incidence of SO following IOS varies between studies. The purpo...

Individual differences in inattentional blindness.

Jan 08, 2024

People often fail to notice unexpected objects and events when they are performing an attention-demanding task, a phenomenon known as inattentional blindness. We might expect individual differences in...

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