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Ophthalmology General

Kearns-Sayre syndrome with a novel large-scale deletion: a case report.

Jan 31, 2022

Kearns-Sayre syndrome (KSS) is a rare, multisystem mitochondrial encephalomyopathy. We report a case of KSS with a novel 7.6-kb deletion as assessed through a long-range polymerase chain reaction (PCR...

From the Obesity Medicine Association - The Alarming Link Between Screen Time & Pediatric Obesity

Jan 26, 2022

It’s nearly impossible to avoid screen time these days; between smartphones, TVs, computers, and tablets, almost everyone’s daily routine revolves around time spent on screens. That includes child...

OPA1 Modulates Mitochondrial Ca Uptake Through ER-Mitochondria Coupling.

Jan 24, 2022

Autosomal Dominant Optic Atrophy (ADOA), a disease that causes blindness and other neurological disorders, is linked to mutations. OPA1, dependent on its GTPase and GED domains, governs inner mitocho...

Retinal Dopamine D2 Receptors Participate in the Development of Myopia in Mice.

Jan 24, 2022

To learn more about the locations of dopamine D2 receptors (D2Rs) that regulate form-deprivation myopia (FDM), using different transgenic mouse models.One eye of D2R-knockout (KO) mice and wild-type l...

Psoriasis and uveitis.

Jan 24, 2022

Psoriasis, which is a chronic, immune-mediated skin disease of unknown etiology, not only affects the skin, but also is linked to many systemic conditions such as arthritis, cardiovascular disease, d...

Impact of Diquafosol Ophthalmic Solution on Tear Film and Dry Eye Symptom in Type 2 Diabetic Dry Eye: A Pilot Study.

Jan 24, 2022

Diquafosol ophthalmic solution (DQS) stimulates P2Y2 receptors on the ocular surface, which enhances mucin secretion from goblet cells. Therefore, tear film stability and hydration of the ocular surf...

STARDUST SIGN AND RETINAL TEAR DETECTION ON SWEPT SOURCE OPTICAL COHERENCE TOMOGRAPHY.

Jan 24, 2022

The causes of floaters include posterior vitreous detachment and fundus hemorrhage, both of which are risk factors for retinal tears. We observed the vitreous of patients with floaters using swept sou...

Congenital primary aphakia.

Jan 24, 2022

To describe the natural history, management, and visual outcome in children with congenital primary aphakia (CPA).This is a multicenter retrospective consecutive case series from five academic centers...

Alginate in corneal tissue engineering.

Jan 24, 2022

Corneal blindness is the major cause of vision impairment and the fourth-largest leading cause of blindness worldwide. An allograft corneal transplant is the most routine treatment for visual loss. Fu...

GWAS identifies two common loci associated with pigment dispersion syndrome/pigmentary glaucoma and implicate myopia in its development.

Jan 17, 2022

- To identify genetic variants associated with pigment dispersion syndrome and pigmentary glaucoma in unrelated patients, and to further understand the genetic and potentially causal relationships bet...

First Experiences with Implantation of Phakic Lenses in Correction of Myopia in R. N. Macedonia.

Jan 17, 2022

Analysis of visual acuity parameters in patients with moderate to high myopia and myopic astigmatism 1 year after treatment with phakic intraocular lenses. This was a retrospective study on 35 patie...

Oculopharyngeal Muscular Dystrophy Ptosis, Mueller's Muscle Involvement, and a Review of Management Over 34 Years.

Jan 17, 2022

To review the management of the ptosis associated with oculopharyngeal muscular dystrophy (OPMD) from one author's experience over 34 years, demonstrate Mueller's muscle involvement in this disease, a...

Efficacy of Artificial Intelligence-based Screening for Diabetic Retinopathy in Type 2 Diabetes Mellitus Patients.

Jan 17, 2022

To explore the efficacy of artificial intelligence (AI)-based screening for diabetic retinopathy (DR) in type 2 diabetes mellitus (T2DM) patients.Data were obtained from 549 T2DM patients who visited ...

Proteomic changes of aqueous humor in proliferative diabetic retinopathy patients treated with different intravitreal anti-VEGF agents.

Jan 17, 2022

Anti-VEGF-based treatment have been regularly used in recent years in proliferative diabetic retinopathy (PDR) patients. However, some of these patients fail to respond effectively to anti-VEGF. Given...

Role and mechanism(s) of incretin-dependent therapies for treating diabetes mellitus.

Jan 17, 2022

Diabetes mellitus (DM) is a worldwide ailment which leads to chronic complications like cardiac disorders, renal perturbations, limb amputation and blindness. Type one diabetes (T1DM), Type two diabet...

Dermatological adverse effects of anti-glaucoma eye drops: a review.

Jan 17, 2022

Many patients are treated for glaucoma. Like other drugs, anti-glaucoma eye drops may induce dermatological adverse effects. We aim to review the dermatological adverse effects secondary to the active...

Evaluation of Artificial Intelligence-Based Intraoperative Guidance Tools for Phacoemulsification Cataract Surgery.

Jan 17, 2022

Complications that arise from phacoemulsification procedures can lead to worse visual outcomes. Real-time image processing with artificial intelligence tools can extract data to deliver surgical guida...

Visual Field Loss Impacts Vision-Specific Quality of Life by Race, Ethnicity: The Multiethnic Ophthalmology Cohorts of California Study.

Jan 17, 2022

To assess the impact of Visual Field Loss (VFL) on Vision-Specific Quality of Life (VSQOL) by race, ethnicity and age DESIGN: Pooled analysis of cross-sectional data from three population-based, prosp...

Arguments for 'ocular donation' as standardised terminology to reduce the 'ick factor' of 'eye donation'.

Jan 10, 2022

This brief report presents the global problem of the shortfall of donor corneal tissue for transplantation, a potential root cause ('ick factor' language), and a potential solution (modification of 'i...

Evaluation of peripapillary - macular microvascularity and choroidal vascularity index after refractive surgery.

Jan 10, 2022

To evaluate the microvascularity and choroidal vascularity index (CVI) using optical coherence tomography angiography (OCTA) and OCT following femtosecond laser-assisted in-situ keratomileusis (FS-LAS...

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