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Ophthalmology General

Effect of preoperative keratometry on visual outcomes after small-incision lenticule extraction for myopia.

Jan 10, 2022

To investigate the relationship between preoperative keratometry (K) and postoperative refraction and compare the visual outcomes after small-incision lenticule extraction (SMILE) between preoperative...

Scleral Lens and Prosthetic Replacement of the Ocular Surface Ecosystem Utilization in Ocular Graft-versus-Host Disease: A Survey Study.

Jan 10, 2022

To evaluate the utilization of scleral lenses and prosthetic replacement of the ocular surface ecosystem devices (SL/PDs) in the management of ocular graft-versus-host disease (oGVHD).A survey of 15 q...

Assessment of meibomian gland drop-out and visibility through a new quantitative method in scleral lens wearers: A one-year follow-up study.

Jan 10, 2022

To validate a previously developed algorithm based on the visibility of meibomian gland images obtained with Cobra fundus camera and to assess the changes in meibomian glands in scleral lens wearers o...

Deep CNN with Hybrid Binary Local Search and Particle Swarm Optimizer for Exudates Classification from Fundus Images.

Jan 10, 2022

Diabetic retinopathy is a chronic condition that causes vision loss if not detected early. In the early stage, it can be diagnosed with the aid of exudates which are called lesions. However, it is ard...

The association between serum interleukin-1 beta and heparin sulphate in diabetic nephropathy patients.

Jan 10, 2022

Inflammation is considered an important mechanism in the development of diabetes mellitus (DM) and persists for a long time before the occurrence of diabetic nephropathy (DN). Many studies have demons...

Functional assays of non-canonical splice-site variants in inherited retinal dystrophies genes.

Jan 10, 2022

Inherited retinal dystrophies are a group of disorders characterized by the progressive degeneration of photoreceptors leading to loss of the visual function and eventually to legal blindness. Althoug...

Visual Outcomes Associated With Patterns of Macular Edema Resolution in Central Retinal Vein Occlusion Treated With Anti-Vascular Endothelial Growth Factor Therapy: A Post Hoc Analysis of the Lucentis, Eylea, Avastin in Vein Occlusion (LEAVO) Trial.

Jan 10, 2022

It is unclear how visual outcomes vary between patterns of macular edema (ME) resolution in eyes with central retinal vein occlusion (CRVO).To assess best-corrected visual acuity (BCVA) outcomes at 10...

Stabilization of refractive error and associated factors following small incision phacoemulsification cataract surgery.

Jan 10, 2022

Accumulating evidence suggests that refractive stabilization occurs rapidly following small incision cataract surgery. Nonetheless, many guidelines still suggest waiting four to 6 weeks before prescri...

Group identity in blindness groups predicts life satisfaction and lower anxiety and depression.

Jan 03, 2022

Group disability identity (GDI) refers to feelings of connection to the disability community. Researchers have proposed that disability identity protects against disability-related stressors. However,...

Decreased Choroidal Blood Perfusion Induces Myopia in Guinea Pigs.

Jan 03, 2022

The development of myopia in guinea pigs can be inhibited by attenuating scleral hypoxia by increasing choroidal blood perfusion (ChBP). In this study, we reduced ChBP through surgical and pharmacolog...

Characterization of the thickness of the Tear Film Lipid Layer in Meibomian Gland Dysfunction using high resolution optical microscopy.

Jan 03, 2022

To evaluate the thickness of the tear film lipid layer (TFLL) in meibomian gland dysfunction (MGD) using a high-resolution optical microscope.The Ocular Surface Disease Index (OSDI) and meibum grade s...

The link module of human TSG-6 (Link_TSG6) promotes wound healing, suppresses inflammation and improves glandular function in mouse models of Dry Eye Disease.

Jan 03, 2022

To investigate the potential of the Link_TSG6 polypeptide comprising the Link module of human TSG-6 (TNF-stimulated gene/protein-6) as a novel treatment for dry eye disease (DED). We analyzed the the...

Long-term Efficacy of a Treat-and-Extend Regimen With Ranibizumab in Patients With Neovascular Age-Related Macular Disease: An Open-label 12-month Extension to the CANTREAT Study.

Jan 03, 2022

To assess the long-term effectiveness of a treat-and-extend (T&E) anti-vascular endothelial growth factor regimen in patients with neovascular age-related macular degeneration who remain on T&...

The role of microRNAs in glaucoma.

Jan 03, 2022

In this review, we aim to provide a comprehensive summary of the various microRNAs (miRNAs) shown to be involved in glaucoma and intraocular pressure regulation. miRNAs are short, single-stranded, and...

Mitochondrial Dysfunction in Primary Open-angle Glaucoma Characterized by Flavoprotein Fluorescence at the Optic Nerve Head.

Jan 03, 2022

To investigate the presence of flavoprotein fluorescence (FPF) at the optic nerve head (ONH) rim as a marker of mitochondrial dysfunction in primary open-angle glaucoma (POAG) and control eyes.Retrosp...

Botulinum Toxin for the Treatment of Hemifacial Spasm: An Update on Clinical Studies.

Dec 27, 2021

Hemifacial spasm (HFS) is a movement disorder characterized by involuntary contractions of the facial muscles innervated by the seventh cranial nerve. Generally, it is associated with a poor quality o...

Progression of myopia in teenagers and adults: a nationwide longitudinal study of a prevalent cohort.

Dec 27, 2021

The prevalence of myopia is increasing worldwide. The purpose of this study was to evaluate the progression of myopia in teenagers and adults in France.This nationwide prospective study followed 630�...

The Association of Choroidal Thickening by Atropine with Treatment Effects for Myopia: Two-Year Clinical Trial of the LAMP Study.

Dec 27, 2021

To evaluate longitudinal changes in subfoveal choroidal thickness (SFChT) among children receiving 0.05%, 0.025%, 0.01% atropine over two-years and their associations with treatment outcomes in myopia...

Mean Tear-Film Lipid Layer Thickness and Video Display Terminal Time as Risk Factors for Abnormal Blinking in Children.

Dec 27, 2021

To explore the risk factors for abnormal blinking in children and the role of the tear-film lipid layer thickness (LLT) as a function of duration of video display terminal (VDT) use in children. Chi...

Formulation and development of tacrolimus-gellan gum nanoformulation for treatment of dry eye disease.

Dec 27, 2021

The present study aimed at the development and evaluation of tacrolimus gellan gum nanoparticles (TGNPs) for the effective management of dry eye disease (DED) following topical application. TGNPs were...

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