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Ophthalmology General

An overview of current alternative models in the context of ocular surface toxicity.

Oct 18, 2021

The 21st century has seen a steadily increasing social awareness of animal suffering, with increased attention to ethical considerations. Developing new integrated approaches to testing and assessment...

Joint Learning of Multi-level Tasks for Diabetic Retinopathy Grading on Low-resolution Fundus Images.

Oct 18, 2021

Diabetic retinopathy (DR) is a leading cause of permanent blindness among the working-age people. Automatic DR grading can help ophthalmologists make timely treatment for patients. However, the existi...

Degree of Myopia and Glaucoma Risk: A Dose-Response Meta-Analysis.

Oct 18, 2021

To verify the dose-response relation between degree of myopia and open-angle glaucoma (OAG) risk DESIGN: Dose-response meta-analysis METHODS: We searched the PubMed, EMBASE, and Cochrane databases for...

Anterior Chamber Laser Flare Photometry After Diode Laser Cyclophotocoagulation.

Oct 18, 2021

The aim of this study was to evaluate changes in intraocular inflammation according to energy delivered per eye during transscleral diode laser cyclophotocoagulation (TDLC) in refractory glaucoma usin...

Blindness in glaucoma: primary open-angle glaucoma versus primary angle-closure glaucoma-a meta-analysis.

Oct 18, 2021

To estimate the risk of blindness with primary angle-closure glaucoma (PACG) compared to primary open-angle glaucoma (POAG) in those population-based studies that reported blindness rates for both PAC...

X-linked Retinoschisis: Novel Clinical Observations and Genetic Spectrum in 340 Patients.

Oct 11, 2021

To describe the natural course, phenotype and genotype of patients with X-linked retinoschisis (XLRS).Retrospective cohort study.Three hundred forty patients with XLRS from 178 presumably unrelated fa...

Single-vision spectacle use and myopia progression in children with low myopia, a propensity score matching study.

Oct 11, 2021

To investigate the impact of single-vision spectacle use on myopia progression in children with low myopia.MYOSOTIS is a prospective myopia screening survey including all 46 primary and junior high sc...

Comparison of subconjunctival microinvasive glaucoma surgery and trabeculectomy.

Oct 11, 2021

To assess surgical success and the post-operative development of intraocular pressure between XEN45 gelstent, Preserflo MicroShunt and trabeculectomy with mitomycin C.Data from 105 eyes from 105 patie...

Efficacy of the Systane iLux Thermal Pulsation System for the Treatment of Meibomian Gland Dysfunction After 1 Week and 1 Month: A Prospective Study.

Oct 11, 2021

To assess 1-week and 1-month efficacy of Systane iLux thermal pulsation treatment for meibomian gland dysfunction (MGD).This prospective, nonrandomized, open-label, multicenter study enrolled 30 adult...

Electrostatic and Covalent Assemblies of Anionic Hydrogel-Coated Gold Nanoshells for Detection of Dry Eye Biomarkers in Human Tears.

Oct 11, 2021

Although dry eye is highly prevalent, many challenges exist in diagnosing the symptom and related diseases. For this reason, anionic hydrogel-coated gold nanoshells (AuNSs) were used in the developmen...

Lycium barbarum polysaccharides attenuates high glucose-induced diabetic retinal angiogenesis by rescuing the expression of miR-15a-5p in RF/6A cells.

Oct 11, 2021

Lycium barbarum L., a classical traditional Chinese Medicine, has long been used to treat ocular diseases. Lycium barbarum polysaccharides (LBP) is an effective component of Lycium barbarum L. with a ...

Racial and socioeconomic differences in eye care utilization among Medicare beneficiaries with glaucoma.

Oct 11, 2021

Evaluate differences in eyecare utilization among glaucoma patients by race and socioeconomic status (SES).Retrospective cohort study.Representative 5% sample of Medicare beneficiaries >65 years wi...

Soft substrate stiffness modifies corneal epithelial stem cell phenotype through hippo-YAP/notch pathway crosstalk.

Oct 11, 2021

Corneal disease remains to be one of the leading causes of blindness in the world and limbal stem cell (LSC) therapy is a promising therapy for LSC deficiency, which is associated with the diseased co...

Health Care Price Transparency in Ophthalmology.

Oct 11, 2021

Health care price transparency legislation is intended to reduce the ambiguity of hospital charges and the resultant financial stress faced by patients.To evaluate the availability, usability, and var...

Modeling congenital cataract in vitro using patient-specific induced pluripotent stem cells.

Oct 04, 2021

Congenital cataracts are the leading cause of childhood blindness. To date, surgical removal of cataracts is the only established treatment, but surgery is associated with multiple complications, whic...

Effect of retinol dehydrogenase gene transfer in a novel rat model of Stargardt disease.

Oct 04, 2021

Dysfunction of the ATPase-binding Cassette Transporter protein (ABCA4) can lead to early onset macular degeneration, in particular to Stargardt disease. To enable translational research into this form...

Brain Activation Induced by Myopic and Hyperopic Defocus From Spectacles.

Oct 04, 2021

To assess neural changes in perceptual effects induced by myopic defocus and hyperopic defocus stimuli in ametropic and emmetropic subjects using functional magnetic resonance imaging (fMRI). This s...

Comparison between estimated and measured myopia progression in Hong Kong children without myopia control intervention.

Oct 04, 2021

To compare myopia progression estimated by the Brien Holden Vision Institute (BHVI) Myopia Calculator with cycloplegic measures in Hong Kong children wearing single-vision distance spectacles over a 1...

Conjunctival impression cytology and tear film parameters in patients with multiple sclerosis.

Oct 04, 2021

To evaluate conjunctival impression cytology (CIC) findings and tear film parameters in patients with multiple sclerosis (MS) compared with controls.Thirty-three patients with MS (MS group) and 33 age...

Topical tacrolimus progylcosomes nano-vesicles as a potential therapy for experimental dry eye syndrome.

Oct 04, 2021

The present work aimed to evaluate the efficacy of topical tacrolimus (0.01%) loaded propylene glycol (PG) modified nano-vesicles (Proglycosomes Nano-vesicles, PNVs) for the treatment of experimental ...

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