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Ophthalmology General

Gene therapy: perspectives from young adults with Leber's congenital amaurosis.

Sep 20, 2021

To investigate Leber congenital amaurosis (LCA) patients' expectations, decision-making processes and gene therapy-related concerns.Using a qualitative approach, we explored perceptions of gene therap...

Outcomes of Cataract Surgeries Performed in Makeshift Operating Rooms in Rural Camps, Compared to Hospital-based Surgeries in Nepal.

Sep 13, 2021

This study was undertaken to evaluate the complication rates and visual outcomes of outreach cataract surgeries done in makeshift operating rooms.In this retrospective study, surgical outcomes of cons...

Deep feed forward neural network-based screening system for diabetic retinopathy severity classification using the lion optimization algorithm.

Sep 13, 2021

Diabetic Retinopathy (DR) has become a major cause of blindness in recent years. Diabetic patients should be screened on a regular basis for early detection, which can help them avoid blindness. Furth...

EFFECT OF PHARMACOLOGICAL PUPIL DILATION ON INTRAOCULAR LENS POWER CALCULATION IN PATIENTS INDICATED FOR CATARACT SURGERY.

Sep 13, 2021

To evaluate the influence of pupil dilation on ocular parameters measured by optical biometry and the influence of pupil dilation on intraocular lens (PC IOL) power calculation by using the third-gene...

Magnitude of astigmatism - A comparison between eyes.

Sep 13, 2021

Astigmatism is a highly prevalent refractive error and while studies typically focus to describe the axis symmetry between eyes, little is known about the refractive symmetry. Therefore, this study de...

Impact of residual astigmatism and defocus in eyes with trifocal intraocular lenses.

Sep 13, 2021

To assess the impact on visual function of different residual astigmatic situations combined with 0.50D negative defocus at different distances in patients with trifocal intraocular lenses (IOLs).Clí...

Comparison of 6.0 mm versus 6.5 mm Optical Zone on Visual Outcomes after LASIK.

Sep 13, 2021

Previous studies have demonstrated safety and efficacy using 6.0 and 6.5 mm optical zones in the WaveLight EX500 Excimer Laser System but have not evaluated if differing optical zone sizes influence r...

Effects of warm compress on tear film, blink pattern and Meibomian gland function in dry eyes after corneal refractive surgery.

Sep 13, 2021

To assess the effects of warm compress (WC) on tear film lipid layer, blink pattern and Meibomian gland function in patients with dry eye following femtosecond laser small incision lenticule extractio...

Ocular Immune-Related Adverse Events Associated With Immune Checkpoint Inhibitors in Lung Cancer.

Sep 13, 2021

Immune checkpoint inhibitors (ICIs) are novel immunotherapy-based drugs that have become increasingly popular in the treatment of lung cancer. Researchers have recognized ocular immune-related adverse...

PRE-RETINOPATHY OF TYPE 1 DIABETES IN THE CONTEXT OF FUNCTIONAL, STRUCTURAL AND MICROCIRCULATORY CHANGES IN THE MACULAR AREA.

Sep 13, 2021

The authors assessed the development of intraocular changes in type 1 diabetes (T1DM) from the onset of the disease leading to diabetic retinopathy (DR). The quote: “There must be an intermediat...

Incidence of diabetic retinopathy in newly diagnosed subjects with type 2 diabetes mellitus over 5 years: Contribution of Β-cell function.

Sep 13, 2021

Identifying and modulating risk factors is essential to prevent visual impairment due to diabetic retinopathy (DR). This study examines incident DR with metabolic and hormonal factors in newly-diagnos...

Fundus Photography as the Base of Three-Tier Diabetic Retinopathy Care System to Its Wider Roles: Learning from a Case Experience.

Sep 13, 2021

A case experience of initiating the ocular fundus photography (OFP) service in a diabetes outpatient clinic of a tertiary-care institution is presented. In the community and within the hospitals, the ...

Prevalence of Type II Diabetes Mellitus Among Adult Population in Medical Department of A Tertiary Care Centre.

Sep 13, 2021

Diabetes mellitus is a chronic metabolic disease that is mainly associated with a number of lifestyle behaviors. There is a high discrepancy among urban and rural populations with the prevalence of di...

Age-related changes in the rhesus macaque eye.

Sep 13, 2021

To assess age-related changes in the rhesus macaque eye and evaluate them to corresponding human age-related eye disease.Data from eye exams and imaging tests including intraocular pressure (IOP), len...

The Effect of Achieving Target Intraocular Pressure on Visual Field Worsening.

Sep 13, 2021

To estimate the effect of achieving target intraocular pressure (IOP) values on visual field (VF) worsening in a treated clinical population.Retrospective analysis of longitudinal data.2,852 eyes of 1...

Atypical macular hole formation after Anti-VEGF therapy for neovascular age-related macular degeneration: Coincidence or consequence?

Sep 06, 2021

Age-related macular degeneration (AMD) is the primary cause of blindness in developed countries, particularly in older adults. Anti-vascular endothelial growth factor (anti-VEGF) intravitreal injectio...

Change in the ophthalmoscopical optic disc size and shape in a 10-year follow-up: the Beijing Eye Study 2001-2011.

Sep 06, 2021

To assess prevalence and associated factors of changes in the ophthalmoscopic optic disc size and shape.The case-control study included all highly myopic eyes (myopic refractive error ≤-6.0 diopters...

Combined fovea-sparing internal limiting membrane peeling with internal limiting membrane flap technique for progressive myopic traction maculopathy.

Sep 06, 2021

To present the anatomical and functional outcomes of combined fovea-sparing internal limiting membrane peeling (FSIP) with internal limiting membrane flap (ILMF) for myopic traction maculopathy (MTM)....

Effect of upper eyelid blepharoplasty on corneal biomechanical, topographic and tomographic parameters 4 weeks after surgery.

Sep 06, 2021

To investigate the effect of "skin-only" upper eyelid blepharoplasty on corneal biomechanics and central as well as peripheral topographic/tomographic parameters before and 4 weeks after surgery.In a...

Direct-acting antivirals inducing HCV-RNA sustained suppression improve Xerophthalmia in HCV-infected patients.

Sep 06, 2021

Hepatitis C virus (HCV) infection represents a global problem, and it is related to both hepatic and extra-hepatic manifestations (e.g., xerophthalmia). New direct-acting antivirals (DAAs), IFN-free t...

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