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Ophthalmology General

Bayesian posterior density estimation reveals degeneracy in three-dimensional multiple emitter localization.

Dec 18, 2023

Single-molecule localization microscopy requires sparse activation of emitters to circumvent the diffraction limit. In densely labeled or thick samples, overlap of emitter images is inevitable. Single...

FL-41 Tint Reduces Activation of Neural Pathways of Photophobia in Patients with Chronic Ocular Pain.

Dec 18, 2023

To assess the therapeutic effect of tinted lenses (FL-41) on photophobia and light-evoked brain activity using functional magnetic resonance imaging (fMRI) in individuals with chronic ocular surface p...

A PEDF peptide mimetic effectively relieves dry eye in a diabetic murine model by restoring corneal nerve, barrier, and lacrimal gland function.

Dec 18, 2023

The study investigated effectiveness of a novel PEDF peptide mimetic to alleviate dry eye-like pathologies in a Type I diabetic mouse model established using streptozotocin.Mice were treated topically...

Effects of CSF1R/p-ERK1/2 signaling pathway on RF/6A cells under high glucose conditions.

Dec 18, 2023

This study analyzed how high glucose affects CSF1R and p-ERK1/2 expression in RF/6A cells.The cells were cultured as high glucose (HG) and normal control (C) groups, and CSF1R shRNA was introduced. Re...

Evaluation of Microvascular Complications in Kidney Recipients with Post-Transplant Diabetes Mellitus.

Dec 18, 2023

Limited data on microvascular complications in patients with post-transplant diabetes (PTDM) is an obstacle to developing follow-up algorithms.To evaluate diabetic microvascular complications in patie...

Application of Patient Sentiment Analysis to Evaluate Glaucoma Care.

Dec 18, 2023

Patients utilize online physician reviews to decide between and rate ophthalmologists. Sentiment analysis allows for better understanding of patient experiences. In this study, Valence Aware Dictionar...

Primary Practice Emphasis Area and Diversity among Board-Certified Ophthalmologists.

Dec 18, 2023

To describe the ophthalmology primary practice emphasis area by underrepresented in medicine (URiM) status using the American Board of Ophthalmology (ABO) Diplomates database.Retrospective cohort stud...

Consensus Guidelines for Ocular Surveillance of von Hippel-Lindau Disease.

Dec 18, 2023

To develop guidelines for ocular surveillance and early intervention for individuals with von Hippel-Lindau (VHL) disease.Systematic review of the literature.Expert panel of retina specialists and ocu...

An evaluation of optometric advanced skills within a UK tertiary based setting.

Dec 18, 2023

Hospital-based optometrists are undertaking extended roles across ophthalmology that may require them to perform advanced skills (AS). Moorfields Eye Hospital (MEH) is the largest UK employer of hospi...

Systemic lupus erythematosus mimicking retinal migraine: a case report.

Dec 11, 2023

Retinal migraine is a diagnosis of exclusion and is characterized by repeated episodes of transient monocular blindness associated with migraine. We report a case of systemic lupus erythematosus with ...

Effect of myopia-control lenses on central and peripheral visual performance in myopic children.

Dec 11, 2023

To evaluate the short-term effects of three myopia-control lenses, which impose peripheral myopic defocus while providing clear central vision, on central and peripheral visual performance in myopic c...

Dry eye disease in the young: A narrative review.

Dec 11, 2023

Dry eye disease (DED), a multifactorial ocular disease that significantly impacts quality of life, is most commonly reported in adults. This review describes the prevalence, risk factors, diagnosis an...

Modified Danzhi Xiaoyao Powder (MDXP) improves the corneal damage in dry eye disease (DED) mice through phagocytosis.

Dec 11, 2023

Modified Danzhi Xiaoyao Powder (MDXP) is a traditional Chinese medicine formula remedy for treating Dry Eye Disease (DED). It showed the function of dispersing stagnated liver Qi for relieving Qi stag...

Exosomes derived from BMSCs alleviates high glucose-induced diabetic retinopathy via carrying miR-483-5p.

Dec 11, 2023

Diabetic retinopathy (DR) is a progressive disease which can cause health problem. It has been reported that bone marrow mesenchymal stem cells (BMSCs)-secreted exosomes could regulate the progression...

Advanced platelet-rich fibrin promotes healing of induced corneal ulcer in donkeys (Equus asinus).

Dec 11, 2023

Ulcerative keratitis is a common disease in horses which may cause blindness. To prevent secondary bacterial and fungal infections and promote quick re-growth of the epithelial layer, different treatm...

Central Visual Field Testing in Early Glaucoma: A Report by the American Academy of Ophthalmology.

Dec 11, 2023

To evaluate the current published literature on the utility of the 10-2 visual field (VF) testing strategy for the evaluation and management of early glaucoma, defined here as mean deviation (MD) bett...

Aqueous Shunts with Extraocular Reservoir for Open-Angle Adult Glaucoma: A Report by the American Academy of Ophthalmology.

Dec 11, 2023

To evaluate the recently published literature on the efficacy and safety of the use of aqueous shunts with extraocular reservoir for the management of adult open-angle glaucomas (OAGs).A search of pee...

Ocular morbidity among children (aged 6-18 yr) of the tribal area of Melghat, India: A community-based study.

Nov 27, 2023

Most of the ocular morbidities among school children are preventable or treatable. Melghat, a difficult to access, hilly, forest, tribal area with poorly developed infrastructure in the Amravati distr...

Treatment of Dry Eye Disease (DED) in Asia: Strategies for Short Tear Film Breakup Time-Type DED.

Nov 27, 2023

Dry eye disease (DED) is a multifactorial disorder in which tear fluid homeostasis is lost, resulting in increased tear film osmolarity and ocular surface irritation. In Asia, the short tear film brea...

Single-Cell Transcriptome Sequencing Unveils Unveils Proinflammatory Microenvironment in Dry Eye Disease

Nov 27, 2023

Dry eye disease (DED) is a prevalent chronic eye disease characterized by an aberrant inflammatory response in ocular surface mucosa. The immunological alterations underlying DED remain largely unknow...

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