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Ophthalmology General

Visualising the choriocapillaris: Histology, imaging modalities and clinical research.

Aug 16, 2021

The choriocapillaris plays a considerable role in the normal physiology of the eye as well as in various diseases. Assessing the changes in the choriocapillaris can therefore provide important informa...

The impact of diabetes on visual acuity in Ethiopia, 2021.

Aug 16, 2021

Diabetes mellitus is a complex metabolic disorder characterized by hyperglycemia that results from defects in insulin secretion, insulin action, or both. Glaucoma is the ocular complication of diabeti...

Novel area-based optic nerve head parameter to distinguish glaucoma from non-glaucomatous retinal nerve fiber layer defect in branch retinal vein occlusion.

Aug 16, 2021

The purpose of this study was to assess the diagnostic ability of the new area-based parameter retinal nerve fiber layer to disc ratio (RDR) for discriminating between glaucoma and non-glaucomatous re...

Effects of acute stress, general anesthetics, tonometry, and temperature on intraocular pressure in rats.

Aug 16, 2021

Intraocular pressure (IOP) is important for eye health as abnormal levels can led to ocular tissue damage. IOP is typically estimated by tonometry, which only provides snapshots of pressure history. T...

Overexpression of BMP4 protects retinal ganglion cells in a mouse model of experimental glaucoma.

Aug 16, 2021

Activation of bone morphogenetic protein (BMP) 4 signaling promotes the survival of retinal ganglion cell (RGC) after acute injury. Chordin-like 1 (CHRDL1) is an endogenous BMP antagonist. In this stu...

Female Editorial Authorship Trends in High-Impact Ophthalmology Journals.

Aug 16, 2021

Individuals with perceived experience and expertise are invited by editorial boards to provide commentary through editorials. Female representation among editorialists is not yet defined.To determine ...

Prednisolone and Ketorolac vs Ketorolac Monotherapy or Sub-Tenon Prophylaxis for Macular Thickening in Cataract Surgery: A Randomized Clinical Trial.

Aug 16, 2021

The choice of anti-inflammatory prophylaxis parallel to cataract surgery is important for patient safety and successful outcome of surgery, but which regimen to choose is contested.To determine whethe...

A Systematic Review of Carotenoids in the Management of Diabetic Retinopathy.

Aug 12, 2021

Diabetic retinopathy, which was primarily regarded as a microvascular disease, is the leading cause of irreversible blindness worldwide. With obesity at epidemic proportions, diabetes-related ocular p...

The Effect of Treatment Discontinuation During the COVID-19 Pandemic on Visual Acuity in Exudative Neovascular Age-Related Macular Degeneration: 1-Year Results.

Aug 12, 2021

To evaluate the effect of a 9-week treatment deferral due to healthcare restrictions caused by Austria's first governmental lockdown associated with the coronavirus disease 2019 (COVID-19) pandemic on...

Metabolomics Analyses of Mouse Retinas in Oxygen-Induced Retinopathy.

Aug 12, 2021

Retinal neovascularization is a severe pathological process leading to irreversible blindness. This study aims to identify the altered metabolites and their related pathways that are involved in retin...

Femtosecond LASIK for the correction of low and high myopic astigmatism.

Aug 12, 2021

Higher preoperative myopic astigmatism is associated with a higher probability of retreatment due to patient dissatisfaction as a result of residual cylindrical error. Nonetheless, retreatment is safe...

Long-Term Changes in Manifest Refraction Subsequent to Cataract Surgery.

Aug 12, 2021

To examine the long-term refractive changes after stabilization of surgically induced changes (SICs) subsequent to cataract surgery.Private hospital.Case-control study.Manifest refraction of 300 eyes ...

Repeatability and comparability of the Galilei-G4 and Cassini in measuring corneal power and astigmatism in normal and post-refractive surgery eyes.

Aug 12, 2021

To assess the repeatability and comparability of the Galilei G4 versus the Cassini topographer in post-refractive eyes and in normal eyes, including older patients representative of an initial catarac...

The effects of tobacco waterpipe smoking on the ocular surface.

Aug 12, 2021

This study was conducted to determine the effect of tobacco waterpipe smoking on the ocular surface. The findings could be useful in understanding ocular surface changes and associated symptoms in wat...

A systematic review assessing the quality of patient reported outcomes measures in dry eye diseases.

Aug 12, 2021

Patient-reported outcome measures (PROMs) can provide valuable insights on the impact of a disease or treatment on a patient's health-related quality of life. In ophthalmology, particularly in dry eye...

Efficacy and safety of a vectored thermal pulsation system (Lipiflow®) in the treatment of meibomian gland dysfunction: a systematic review and meta-analysis.

Aug 12, 2021

To investigate the efficacy and safety of a vectored thermal pulsation system (Lipiflow®) in the treatment of dry eye disease resulting from meibomian gland dysfunction (MGD).We searched for randomiz...

A Review to Populate A Proposed Cost-Effectiveness Analysis of Glaucoma Screening in Sub-Saharan Africa.

Aug 12, 2021

To populate a proposed cost-effectiveness analysis of glaucoma screening in Sub-Saharan Africa (SSA).A complete search was conducted on PubMed, Medline and African Journals Online (AJOL) to obtain rel...

Deep learning-enabled ultra-widefield retinal vessel segmentation with an automated quality-optimized angiographic phase selection tool.

Aug 12, 2021

To demonstrate the feasibility of a deep learning-based vascular segmentation tool for UWFA and evaluate its ability to automatically identify quality-optimized phase-specific images.Cumulative retina...

Diagnostic performance of deep-learning-based screening methods for diabetic retinopathy in primary care-A meta-analysis.

Aug 12, 2021

Diabetic retinopathy (DR) affects 10-24% of patients with diabetes mellitus type 1 or 2 in the primary care (PC) sector. As early detection is crucial for treatment, deep learning screening methods in...

Forkhead domain inhibitory-6 attenuates subconjunctival fibrosis in rabbit model with trabeculectomy.

Aug 12, 2021

Antiproliferative therapies are crucially important for improving the success rate of the glaucoma filtration surgeries. In this study, we investigated the potential efficacy of Forkhead Domain Inhibi...

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