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Ophthalmology General

Identification of novel key molecular signatures in the pathogenesis of experimental diabetic retinopathy.

Aug 19, 2021

Deep mining of the molecular mechanisms underlying diabetic retinopathy (DR) is critical for the development of novel therapeutic targets. This study aimed to identify key molecular signatures involve...

Performance and Limitation of Machine Learning Algorithms for Diabetic Retinopathy Screening: Meta-analysis.

Aug 19, 2021

Diabetic retinopathy (DR), whose standard diagnosis is performed by human experts, has high prevalence and requires a more efficient screening method. Although machine learning (ML)-based automated DR...

Intraocular Pressure Reduction by Femtosecond Laser Created Trabecular Channels in Perfused Human Anterior Segments.

Aug 19, 2021

This study investigated the initial feasibility of using femtosecond laser trabeculotomy (FLT) to create open channels through the trabecular meshwork into Schlemm's canal to lower intraocular pressur...

Effects of topical low-dose preservative-free hydrocortisone on intraocular pressure in patients affected by ocular surface disease with and without glaucoma.

Aug 19, 2021

This study aims to investigate the safety and efficacy of short-term treatment for ocular surface disease (OSD) with topical low-dose (1,005 mg) preservative-free hydrocortisone in one hundred patien...

Erythropoietin is not a risk factor for severe retinopathy of prematurity among high risk preterm infants.

Aug 19, 2021

Retinopathy of prematurity (ROP) is a developmental retinal vaso-proliferative disease and a leading cause of blindness in children. Early gestational age, low birth weight and unregulated oxygen expo...

Association of Retinal Vascular Manifestation and Obstructive Sleep Apnea (OSA): A Narrative Review.

Aug 19, 2021

Obstructive sleep apnea (OSA) is characterized by frequent episodes of partial or complete obstruction of the airway during sleep causing repeated episodes of apnea. OSA is more prevalent in middle-ag...

Altered Metabolic Phenotype of Immune Cells in a Spontaneous Autoimmune Uveitis Model.

Aug 16, 2021

As one of the leading causes of blindness worldwide, uveitis is an important disease. The exact pathogenesis of autoimmune uveitis is not entirely elucidated to date. Equine recurrent uveitis (ERU) re...

Parental stress around ophthalmological health conditions: a systematic review of literature protocol.

Aug 16, 2021

Parents can be psychologically impacted when their children are diagnosed with eye diseases, such as blindness, strabismus, and eye cancer. Stress can reduce the quality of parental care and may be li...

Comparison of IOL Power Calculation Formulas for a Trifocal IOL in Eyes With High Myopia.

Aug 16, 2021

To analyze the results of new intraocular lens (IOL) formulas (Emmetropia Verifying Optical [EVO], Kane, Olsen, and Barrett Universal II), traditional formulas (Haigis and SRK/T), and modified Wang-Ko...

Small Incision Lenticule Extraction for Correction of Pediatric Unilateral Anisometropic Myopia.

Aug 16, 2021

To evaluate the effects of femtosecond laser small incision lenticule extraction (SMILE) on treating unilateral myopic anisometropia in children with spectacles or contact lens intolerance.This was a ...

Association of high myopia with peripapillary retinal nerve fiber layer in patients with hypertension.

Aug 16, 2021

To identify the impacts of hypertension (HTN), high myopia, and the combination thereof on peripapillary retinal nerve fiber layer (pRNFL) thickness.All subjects were divided into four groups: control...

Effect of microincisional cataract surgery on inflammatory indicators in tears and corneal endothelial cells in cataract patients.

Aug 16, 2021

To analyze the effect of microincisional cataract surgery on inflammation in tears and corneal endothelial cells in cataract patients.A total of 103 patients with cataracts in our hospital were enroll...

Assessment of receptor affinities of ophthalmic and systemic agents in dry eye disease.

Aug 16, 2021

To explore our current understanding of receptor profiles acted upon by medications used to treat dry eye disease (DED).Research into histaminic and muscarinic receptor affinities for drugs targeting ...

regulated diabetic retinal epithelial-mesenchymal transition through regulating miR-204/SOX4 axis.

Aug 16, 2021

Epithelial-mesenchymal transition (EMT) of retinal pigment epithelium (RPE) cells is the key of the development of diabetic retinopathy (DR), and lncRNA NEAT1 could accelerate EMT in diabetic nephropa...

Visualising the choriocapillaris: Histology, imaging modalities and clinical research.

Aug 16, 2021

The choriocapillaris plays a considerable role in the normal physiology of the eye as well as in various diseases. Assessing the changes in the choriocapillaris can therefore provide important informa...

The impact of diabetes on visual acuity in Ethiopia, 2021.

Aug 16, 2021

Diabetes mellitus is a complex metabolic disorder characterized by hyperglycemia that results from defects in insulin secretion, insulin action, or both. Glaucoma is the ocular complication of diabeti...

Novel area-based optic nerve head parameter to distinguish glaucoma from non-glaucomatous retinal nerve fiber layer defect in branch retinal vein occlusion.

Aug 16, 2021

The purpose of this study was to assess the diagnostic ability of the new area-based parameter retinal nerve fiber layer to disc ratio (RDR) for discriminating between glaucoma and non-glaucomatous re...

Effects of acute stress, general anesthetics, tonometry, and temperature on intraocular pressure in rats.

Aug 16, 2021

Intraocular pressure (IOP) is important for eye health as abnormal levels can led to ocular tissue damage. IOP is typically estimated by tonometry, which only provides snapshots of pressure history. T...

Overexpression of BMP4 protects retinal ganglion cells in a mouse model of experimental glaucoma.

Aug 16, 2021

Activation of bone morphogenetic protein (BMP) 4 signaling promotes the survival of retinal ganglion cell (RGC) after acute injury. Chordin-like 1 (CHRDL1) is an endogenous BMP antagonist. In this stu...

Female Editorial Authorship Trends in High-Impact Ophthalmology Journals.

Aug 16, 2021

Individuals with perceived experience and expertise are invited by editorial boards to provide commentary through editorials. Female representation among editorialists is not yet defined.To determine ...

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