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Ophthalmology General

Strain by virtual extensometers and video-imaging optical coherence tomography as a repeatable metric for IOP-Induced optic nerve head deformations.

Aug 12, 2021

To determine if in vivo strain response of the Optic Nerve Head (ONH) to IOP elevation visualized using Optical Coherence Tomography (OCT) video imaging and quantified using novel virtual extensometer...

Brachytherapy for Peripheral Retinal Capillary Haemangioblastoma in von Hippel-Lindau Disease.

Aug 12, 2021

To report our experience with ruthenium-brachytherapy of peripheral capillary haemangioblastomas in patients with von Hippel-Lindau disease.Retrospective case series.A total of 53 haemangioblastomas, ...

A simple eye model for objectively assessing the competency of direct ophthalmoscopy.

Aug 12, 2021

Direct ophthalmoscopy is an important investigative technology not only for ophthalmologists, but also for general practitioners and other specialists. The purpose of this study was to develop a simpl...

Prevention of the Onset of Age-Related Macular Degeneration.

Aug 09, 2021

Age-related macular degeneration (AMD) represents the leading cause of irreversible blindness in elderly people, mostly after the age of 65. The progressive deterioration of visual function in patient...

XIAP gene therapy effects on retinal ganglion cell structure and function in a mouse model of glaucoma.

Aug 09, 2021

Glaucoma is a prevalent neurodegenerative disease that is characterized by progressive visual field loss. It is the leading cause of irreversible blindness in the world. The main risk factor for glauc...

The association of myopia progression with the morphological changes of optic disc and β-peripapillary atrophy in primary school students.

Aug 09, 2021

To study the association of myopia progression with the morphological changes of optic disc and β-peripapillary atrophy (β-PPA) in 8-11 years old primary school students.This study was a prospectiv...

Customized eye modeling for optical quality assessment in myopic femto-LASIK surgery.

Aug 09, 2021

Refractive surgery is recognized as an effective method for myopia treatment, but it can induce night vision disturbances such as glare. We present an eye modeling method for the optical quality asses...

Integrins: An Important Link between Angiogenesis, Inflammation and Eye Diseases.

Aug 09, 2021

Integrins belong to a group of cell adhesion molecules (CAMs) which is a large group of membrane-bound proteins. They are responsible for cell attachment to the extracellular matrix (ECM) and signal t...

Inhibition of Aberrant α(1,2)-Fucosylation at Ocular Surface Ameliorates Dry Eye Disease.

Aug 09, 2021

Fucosylation is involved in a wide range of biological processes from cellular adhesion to immune regulation. Although the upregulation of fucosylated glycans was reported in diseased corneas, its imp...

A spectroscopic approach to measuring meibum lipid composition and conformation in donors with Sjӧgren's syndrome.

Aug 09, 2021

Patients with Sjӧgren's syndrome (SS) have dry eye associated with meibomian gland dysfunction (MGD). The meibum from donors with dry eye due to MGD but without SS (M) presents with lower levels of c...

Human Leukocyte Antigens class II (HLA II) gene profile from an admixed population of patients with type 1 diabetes with severe diabetic retinopathy: a nested case-control study in Brazil.

Aug 09, 2021

Although the well-established role of the HLA genes on the predisposition of type 1 diabetes (T1D), its contribution to the development and progression of diabetic retinopathy is still unclear, especi...

DNMT1-mediated PPARα methylation aggravates damage of retinal tissues in diabetic retinopathy mice.

Aug 09, 2021

Peroxisome proliferator-activated receptor alpha (PPARα) is associated with diabetic retinopathy (DR), and the underlying mechanism is still unclear. Aim of this work was to investigate the mechanism...

Support vector machine and deep-learning object detection for localisation of hard exudates.

Aug 09, 2021

Hard exudates are one of the main clinical findings in the retinal images of patients with diabetic retinopathy. Detecting them early significantly impacts the treatment of underlying diseases; theref...

Vascular biomarkers from optical coherence tomography angiography and glaucoma: where do we stand in 2021?

Aug 09, 2021

Biomarkers of ocular blood flow originating from a wide variety of imaging modalities have been associated with glaucoma onset and progression for many decades. Advancements in imaging platforms inclu...

The Layered Anatomy of the Nose: An Ultrasound-Based Investigation.

Aug 09, 2021

An increasing number of soft tissue filler procedures in the nasal region has been reported. Concomitant with demand, the number of complications has risen due to the difficulty in administering fille...

Comparing a Home Vision Self-Assessment Test to Office-Based Snellen Visual Acuity.

Aug 09, 2021

To evaluate the agreement of a home vision screening test compared to standard in-office technician-measured Snellen visual acuity to allow for remote screening and triaging of patients.In this prospe...

Ophthalmic Injuries After the Port of Beirut Blast-One of Largest Nonnuclear Explosions in History.

Aug 09, 2021

A review of the injury patterns, treatment strategies, and responding physicians' experience during the Port of Beirut blast may help guide future ophthalmic disaster response plans.To present the oph...

Review: Perspective on ocular toxicity of presurgical skin preparations utilizing Chlorhexidine Gluconate/Hibiclens/Chloraprep.

Aug 05, 2021

Chlorhexidine Gluconate (CHG), Hibiclens (4% CHG with 4% Isopropyl Alcohol Detergent), and Chloraprep (i.e. labeled CHG-based solutions), utilized as preoperative surgical preparatory solutions may al...

Associations of refractive errors and retinal changes measured by optical coherence tomography: A systematic review and meta-analysis.

Aug 05, 2021

Studies reporting alteration in retinal thickness using optical coherence tomography (OCT) have been performed in different populations and various degrees of refractive error, producing inconsistent ...

Missense mutation in the gene can cause a complex mild variable phenotype predominated by concomitant strabismus.

Aug 05, 2021

We aimed to reveal the underlying genetic defect in a multigenerational Chinese family with autosomal dominant concomitant strabismus complicated by multiple ocular developmental abnormalities.Compreh...

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