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Ophthalmology General

Spotlight on the Corneal Back Surface Astigmatism: A Review.

Aug 05, 2021

Recent evidence indicates that the corneal back surface astigmatism (CBSA) contributes to the refractive state of the eye in cataract surgery, especially with the implantation of toric intraocular len...

Evaluation of the Repeatability of the LacryDiag Ocular Surface Analyzer for Assessment of the Meibomian Glands and Tear Film.

Aug 05, 2021

This study aimed to determine the intra- and interobserver repeatability of the new LacryDiag Ocular Surface Analyzer and compare it to a similar all-in-one device, the OCULUS Keratograph 5M.Thirty he...

The role of topical N-acetylcysteine in ocular therapeutics.

Aug 05, 2021

N-acetylcysteine (NAC) was first discovered as a mucolytic agent in 1960. We investigate the role of topical NAC in ocular therapeutics, including its mechanism of action, current applications, and ad...

[A multicenter, randomized, double-masked, placebo-controlled trial of compound wild chrysanthemum eye masks for mild and moderate dry eye].

Aug 05, 2021

To investigate the clinical efficacy and safety of compound wild chrysanthemum eye masks for mild and moderate dry eye. In this double-masked, multicenter, placebo-controlled, randomized trial, midd...

Nuclear factor of activated T-cells (NFAT) regulation of IL-1β-induced retinal vascular inflammation.

Aug 05, 2021

Chronic low-grade retinal inflammation is an essential contributor to the pathogenesis of diabetic retinopathy (DR). It is characterized by increased retinal cell expression and secretion of a variety...

Metabolomics in Diabetic Retinopathy: A Systematic Review.

Aug 05, 2021

Diabetic retinopathy (DR), a common microvascular complication of diabetes, is the leading cause of acquired blindness in the working-age population. Individuals with diabetes still develop DR despite...

Proliferative diabetic retinopathy treated with intravitreal ranibizumab and photocoagulation directed at ischemic retinal areas-A randomized study.

Aug 05, 2021

To compare ETDRS panretinal laser photocoagulation (PRP) combined with intravitreal injection of ranibizumab (IVR) and photocoagulation targeted to ischemic retina (PIR) combined with IVR in patients ...

Menstrual hygiene management strategies used by women who are blind or have low vision.

Aug 05, 2021

Menstrual hygiene management is a global public health issue that requires local and individualized support to reduce activity limitations and enable safe, independent task performance for people with...

Stimulation of α7 nAChR leads to regeneration of damaged neurons in adult mammalian retinal disease models.

Aug 05, 2021

The adult mammal lacks the ability to regenerate neurons lost to retinal damage or disease in a meaningful capacity. However, previous studies from this laboratory have demonstrated that PNU-282987, a...

Molecular regulation of neuroinflammation in glaucoma: Current knowledge and the ongoing search for new treatment targets.

Aug 05, 2021

Neuroinflammation relying on the inflammatory responses of glial cells has emerged as an impactful component of the multifactorial etiology of neurodegeneration in glaucoma. It has become increasingly...

Differentiating Diagnosed and Undiagnosed Primary Angle-Closure Glaucoma and Open-Angle Glaucoma: A Population-Based Study.

Aug 05, 2021

To study and compare factors contributing to the differentiation of diagnosed and undiagnosed primary angle-closure glaucoma (PACG) and primary open-angle glaucoma (POAG) in the same population.Popula...

Paraneoplastic ocular syndrome: a pandora's box of underlying malignancies.

Aug 05, 2021

Paraneoplastic syndromes affecting the visual system are a group of conditions that arise in the systemic malignancy framework. In this review, we have provided a detailed and comprehensive overview o...

A core-shell nanoplatform as a nonviral vector for targeted delivery of genes to the retina.

Aug 02, 2021

Retinal diseases, including age-related macular degeneration (AMD), are a major cause of blindness. Efficient delivery of therapeutic genes to retinal cells to treat retinal disease is a formidable ch...

Using electronic health records to develop and validate a machine-learning tool to predict type 2 diabetes outcomes: a study protocol.

Aug 02, 2021

Type 2 diabetes mellitus (T2DM) is a major cause of blindness, kidney failure, myocardial infarction, stroke and lower limb amputation. We are still unable, however, to accurately predict or identify ...

A Novel Stimuli-Responsive Injectable Antibacterial Hydrogel to Achieve Synergetic Photothermal/Gene-Targeted Therapy towards Uveal Melanoma.

Aug 02, 2021

Uveal melanoma (UM) is the most prevalent primary intraocular malignant tumor with a high lethal rate. Patients who undergo conventional enucleation treatments consistently suffer permanent blindness,...

Prevalence and time trends of refractive error in Chinese children: A systematic review and meta-analysis.

Aug 02, 2021

To investigate the prevalence and time trends of refractive error (RE) among Chinese children under 18 years old.PubMed, Embase, Web of Science were searched for articles that estimated prevalence of ...

Multiple Evanescent White Dot Syndrome (MEWDS) Associated with Progression of Lacquer Cracks in High Myopia.

Aug 02, 2021

To report a case of multiple evanescent white dot syndrome (MEWDS) associated with acute progression of lacquer cracks in high myopia.A 41-year-old female patient with high myopia developed typical si...

Biomechanics of Ophthalmic Crosslinking.

Aug 02, 2021

Crosslinking involves the formation of bonds between polymer chains, such as proteins. In biological tissues, these bonds tend to stiffen the tissue, making it more resistant to mechanical degradation...

Clinical evaluation of meibomian gland dysfunction in patients with keratoconus.

Aug 02, 2021

To investigate the association of keratoconus (KC) with meibomian gland dysfunction (MGD) and to describe the epidemiological characteristics of MGD in this disease.In this observational study, 120 KC...

The ocular surface findings in alopecia areata patients: clinical parameters and impression cytology.

Aug 02, 2021

The objective of this study was to examine the effects of alopecia areata (AA) on the ocular surface and conjunctival cytology.A total of 48 subjects were included in the present study. Twenty-three s...

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