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Ophthalmology General

Tear metabolomics highlights new potential biomarkers for differentiating between Sjögren's syndrome and other causes of dry eye.

Aug 02, 2021

The lacrimal exocrinopathy of primary Sjögren's syndrome (pSS) is one of the main causes of severe dry eye syndrome and a burden for patients. Early recognition and treatment could prevent irreversib...

Association between Dietary Choline Intake and Diabetic Retinopathy: National Health and Nutrition Examination Survey 2005-2008.

Aug 02, 2021

To explore whether there is an association between dietary choline intake and odds of diabetic retinopathy (DR) in the US diabetic population.A cross-sectional study was conducted using the combined d...

Multi-label classification of fundus images based on graph convolutional network.

Aug 02, 2021

Diabetic Retinopathy (DR) is the most common and serious microvascular complication in the diabetic population. Using computer-aided diagnosis from the fundus images has become a method of detecting r...

Five regions, five retinopathy screening programmes: a systematic review of how Portugal addresses the challenge.

Aug 02, 2021

The implementation of a population-based screening programme for diabetic retinopathy involves several challenges, often leading to postponements and setbacks at high human and material costs. Thus, i...

PRESERFLO™ MicroShunt versus trabeculectomy: first results on efficacy and safety.

Aug 02, 2021

To report efficacy and safety outcomes of the PRESERFLO™ MicroShunt compared with trabeculectomy, the current gold-standard treatment for advanced glaucoma, in the early and intermediate postop...

Incidence of ocular hypertension in patients receiving intravitreal anti-VEGF injections: comparing filtered drug in plastic silicone-free syringes to nonfiltered drug in silicone-lined insulin plastic syringes.

Aug 02, 2021

To examine the difference in incidence of ocular hypertension (OHT) following the introduction of filtered anti-vascular endothelial growth factor (anti-VEGF) medication in silicone-free syringes.Retr...

Cyclodextrin-based formulation of carbonic anhydrase inhibitors for ocular delivery - A review.

Aug 02, 2021

Carbonic anhydrase inhibitors (CAIs) are used as systemic and topical agents for lowering intraocular pressure (IOP) in patients with glaucoma. Owing to the wide distribution of CAs and their physiolo...

Microbial Contamination of Extended Use Ophthalmic Drops in Ophthalmology Clinic.

Aug 02, 2021

The objectives of this study were to determine the prevalence of microbial contamination of multi-user preserved ophthalmic drops (POD) in Ophthalmology Outpatient Clinic (OOC), to compare the rate of...

Recommendations for Dosing & Administering Medical Cannabis for Chronic Pain

Jul 31, 2021

Despite a need for more robust evidence, many patients with chronic pain are being treated with medical cannabis and cannabinoids. In the Journal of Cannabis Research, the Global Task Force on Dosing ...

Nrf2 deficiency decreases NADPH from impaired IDH shuttle and pentose phosphate pathway in retinal pigmented epithelial cells to magnify oxidative stress-induced mitochondrial dysfunction.

Jul 29, 2021

The nuclear factor-erythroid 2-related factor-2 (Nrf2), a major antioxidant transcription factor, is decreased in several age-related diseases including age-related macular degeneration (AMD), the mos...

Outcomes of toric IOL implantation guided by iris-registered femtosecond laser capsulotomy markings.

Jul 29, 2021

To assess the accuracy and stability of iris-registered femtosecond laser-assisted anterior capsule axis markings (compensating cyclotorsion) along with refractive and visual outcomes after toric IOL ...

Carbon myopia: the urgent need for integrated social, economic and environmental action in the livestock sector.

Jul 29, 2021

Livestock have long been integral to food production systems, often not by choice but by need. While our knowledge of livestock greenhouse gas emissions (GHG) mitigation has evolved, the prevailing fo...

Ocular Biometric Characteristics Measured by Swept-Source Optical Coherence Tomography in Individuals Undergoing Cataract Surgery.

Jul 29, 2021

To study the distribution of ocular biometric parameters utilizing a swept-source optical coherence tomography (SS-OCT) biometer in adult candidates for cataract surgery.A retrospective cross-sectiona...

The importance of tears stability in SARS-CoV-2 transmission: COVID-19 prevalance in dry eye patients.

Jul 29, 2021

To investigate whether dry eye disease (DED) is a risk factor for COVID-19.In this retrospective cohort study, patients who were diagnosed with DED by an ophthalmologist and whose Schirmer test was le...

Correlation of Measures From the OCULUS Keratograph and Clinical Assessments of Dry Eye Disease in the Dry Eye Assessment and Management Study.

Jul 29, 2021

The purpose of this study was to compare objective, noninvasive assessments of tear function using the OCULUS Keratograph with the corresponding clinical assessments [tear break-up time (TBUT), Schirm...

Physiological and pathophysiological roles of acidic mammalian chitinase (CHIA) in multiple organs.

Jul 29, 2021

Acidic mammalian chitinase (CHIA) belongs to the 18-glycosidase family and is expressed in epithelial cells and certain immune cells (such as neutrophils and macrophages) in various organs. Under phys...

The Impact of Delayed Anti-vascular Endothelial Growth Factor Treatment for Retinal Diseases During the COVID-19 Lockdown.

Jul 29, 2021

To assess the clinical status of treatment-naive patients who had to delay 3-dose loading anti-VEGF (anti-vascular endothelial growth factor) injections during the COVID-19 lockdown, and to evaluate t...

Current Status and Associated Factors of Annual Eye Examination Among People with Type 2 Diabetes Mellitus: Using the 7th National Health and Nutrition Examination Survey.

Jul 29, 2021

To evaluate the level of annual eye examination (AEE) and identify the associated factors among people with diabetes mellitus (DM).A secondary data analysis was conducted using data from the Korean Na...

Inhibition of the HIF-1α/BNIP3 pathway has a retinal neuroprotective effect.

Jul 29, 2021

Retinal ischemia is a leading cause of irreversible blindness worldwide. Inner retinal dysfunction including loss of retinal ganglion cells is encountered in a number of retinal ischemic disorders. We...

Multicolor imaging for detection of retinal nerve fiber layer defect in myopic eyes with glaucoma.

Jul 29, 2021

To investigate the diagnostic performance of multicolor imaging for detection of retinal nerve fiber layer (RNFL) defect in myopic eyes with glaucoma.Comparative diagnostic analysis.A total of 150 myo...

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