Jul 08, 2021

Evaluation of marketed eye drops with or without trehalose, a nonreducing natural osmoprotector disaccharide, in autophagy modulation and its role in cell survival during desiccation. Eye drops cont...

Jul 08, 2021

Given the association of diabetic retinopathy (DR) and kidney disease, we investigated the urinary proteome to presence and deterioration of DR in a post hoc analysis of trials investigating the effec...

Jul 08, 2021

Diabetic retinopathy (DR) is one of the common complications in diabetic patients. Nowadays, VEGF pathway is subject to extensive research. However, about 27% of the patients have a poor visual outcom...

Jul 08, 2021

Despite advances in the treatments of diabetic complications, proliferative diabetic retinopathy (PDR) still remains a major cause leading to visual loss, mainly because of the lack of pathological me...

Jul 08, 2021

The dynamic contour tonometer PASCAL (DCT) is a direct noninvasive digital tonometer matching the corneal contour. We compared the DCT with the Goldmann applanation tonometer (GAT).A total of 100 eye...

Jul 08, 2021

Intraocular pressure reduction is the only available and evidence-based medical therapy for glaucoma. Currently, the first-line eye drops are prostaglandin analogues including latanoprost, travoprost,...

Jul 08, 2021

British-American ophthalmologist Edward Perkins, MD, PhD (1919-2015) held wide-ranging research interests during his career at the Institute of Ophthalmology in London, the University of Iowa, and as ...

Jul 08, 2021

As gonococcal infections continue to increase, we wanted to review the number and clinical course of recent ocular gonococcal cases presenting to ophthalmology departments in NHS Greater Glasgow and C...

Jul 08, 2021

This prospective, observational cohort study of 116 patients found that residents could participate in ∼40% of vitreoretinal surgery cases with good visual and anatomical outcomes. Ophthalmology res...

Jul 05, 2021

Glaucoma is the leading cause of irreversible blindness worldwide. The proteome characterization of glaucoma is not clearly understood. A total of 175 subjects, including 57 primary acute angle-closur...

Jul 05, 2021

Cataract surgery is very important to prevent blindness, but its productivity and efficiency in China are unknown. Our study aimed to evaluate the geographical distribution of cataract surgeons and pr...

Jul 05, 2021

The vertebrate retina develops from a specified group of precursor cells that adopt distinct identities and generate lineages of either the neural retina, retinal pigmented epithelium, or ciliary body...

Jul 05, 2021

Nitric oxide (NO) is acknowledged as a vital intercellular messenger in multiple systems in the body. Medicine has focused on its functions and therapeutic applications for decades, especially in card...

Jul 05, 2021

Evaluation of real-world outcomes of intravitreal anti-vascular endothelial growth factor (anti-VEGF) therapy in the primary treatment of choroidal neovascularization (CNV) secondary to pathological m...

Jul 05, 2021

Dry eye is one of the most common ocular surface disorders. Although artificial tear drops therapy is the most widely used treatment, it has recently been suggested that autologous serum could be a be...

Jul 05, 2021

To evaluate the safety of Fecal Microbial Transplant (FMT) in individuals with immune-mediated dry eye (DE).Open-label, non-randomized clinical trial.Ten individuals with DE symptoms and signs meeting...

Jul 05, 2021

Sjögren's syndrome is rare in children and most often secondary. It frequently affects girls and is characterized by dry eye syndrome, mouth and sometimes systemic involvement. Its diagnosis is diffi...

Jul 05, 2021

In this study, we test the hypothesis that diabetes promotes a greater than normal cytosolic calcium level in rod cells that activates a Ca-sensitive protease, calpain, resulting in oxidative stress a...

Jul 05, 2021

This article aims to review the impact of detecting and quantifying intraocular biomarkers (liquid biopsy) in both aqueous and vitreous humor in eyes of people affected by diabetes mellitus.This is a ...

Jul 05, 2021

We previously found the mutation frequency of cytoskeleton-associated protein 2 (CKAP2) was significantly increased in proliferative diabetic retinopathy (PDR) patients through whole exome sequencing....