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Ophthalmology General

Prevalence of primary open angle glaucoma in the last 20 years: a meta-analysis and systematic review.

Jul 05, 2021

Primary open-angle glaucoma (POAG) is a leading cause of irreversible blindness in the world and is influenced by various sociodemographic factors. This meta-analysis aims to determine the worldwide p...

Colour Doppler imaging of retrobulbar circulation in different severity of glaucoma optic neuropathy.

Jul 05, 2021

To compare retrobulbar hemodynamic measured by colour Doppler imaging (CDI) in patients with a different severity of glaucoma and to correlate variables CDI with the structural parameters of the retin...

Predictive models of aging of the human eye based on ocular anterior segment morphology.

Jul 05, 2021

Aging is a major risk factor for various eye diseases, such as cataract, glaucoma, and age-related macular degeneration. Age-related changes are observed in almost all structures of the human eye. Con...

The American Glaucoma Society 100: Articles with Significant Impact on Clinical Glaucoma Care.

Jul 05, 2021

To identify 100 articles with significant impact on the clinical care of patients with glaucoma.Cross-sectional study.108 members of the American Glaucoma Society (AGS) in the original survey and 63 i...

Five-year review of ocular Neisseria gonorrhoeae infections presenting to ophthalmology departments in Greater Glasgow & Clyde, Scotland.

Jul 05, 2021

As gonococcal infections continue to increase, we wanted to review the number and clinical course of recent ocular gonococcal cases presenting to ophthalmology departments in NHS Greater Glasgow and C...

Prevalence, Patterns, and Characteristics of Eye Injuries in Professional Mixed Martial Arts.

Jul 05, 2021

To describe the frequency and type of eye injuries in fighters in mixed martial arts (MMA) competition.Fight result data were collected from the Nevada Athletic Commission database from 2001 to 2020. ...

TPC2 promotes choroidal angiogenesis and inflammation in a mouse model of neovascular age-related macular degeneration.

Jul 01, 2021

Age-related macular degeneration (AMD) is the most common cause of blindness among the elderly and can be classified either as dry or as neovascular (or wet). Neovascular AMD is characterized by a str...

Automated segmentation of macular edema for the diagnosis of ocular disease using deep learning method.

Jul 01, 2021

Macular edema is considered as a major cause of visual loss and blindness in patients with ocular fundus diseases. Optical coherence tomography (OCT) is a non-invasive imaging technique, which has bee...

Cationic Polyelectrolyte Nanocapsules of Moxifloxacin for Microbial Keratitis Therapy: Development, Characterization, and Pharmacodynamic Study.

Jul 01, 2021

Microbial keratitis (MK) is a vision-threatening disease and the fourth leading cause of blindness worldwide. In this work, we aim to develop moxifloxacin (MXN)-loaded chitosan-based cationic mucoadhe...

Centration of myopic refractive ablation: should we center treatment on the pupil or the visual axis?

Jul 01, 2021

The purpose of this study is to compare pupil versus corneal vertex-centered ablation for myopic laser refractive surgery. This study is a retrospective case series of right eyes of consecutive myopi...

Regional analysis of segmented-macular structure in patients with myopic anisometropia.

Jul 01, 2021

To compare intraretinal layers between the eyes in patients with myopic anisometropia, and evaluate the relationship between the layers with spherical equivalent (SE) and axial length (AL).In this ret...

Towards transforming community eye care: an observational study and time-series analysis of optometrists' prescribing for eye disorders.

Jul 01, 2021

This study aimed to provide evidence on the therapeutic prescribing activity by community optometrists in Scotland and to determine its impact on workload in general practice and ophthalmology clinics...

Corneal neuropathic pain in irritable bowel syndrome: clinical findings and in vivo corneal confocal microscopy.

Jul 01, 2021

Ocular discomfort is a common symptom in central sensitization syndromes. The aim of this study was to evaluate ocular surface discomfort and related corneal changes in patients with irritable bowel s...

Mucin-Like Glycoproteins Modulate Interfacial Properties of a Mimetic Ocular Epithelial Surface.

Jul 01, 2021

Dry eye disease (DED) has high personal and societal costs, but its pathology remains elusive due to intertwined biophysical and biochemical processes at the ocular surface. Specifically, mucin defici...

Probabilistic Forecasting of Anti-VEGF Treatment Frequency in Neovascular Age-Related Macular Degeneration.

Jul 01, 2021

To probabilistically forecast needed anti-vascular endothelial growth factor (anti-VEGF) treatment frequency using volumetric spectral domain-optical coherence tomography (SD-OCT) biomarkers in neovas...

Emerging roles of exosomal miRNAs in diabetes mellitus.

Jul 01, 2021

Exosomes are small extracellular vesicles 40-160 nm in diameter that are secreted by almost all cell types. Exosomes can carry diverse cargo including RNA, DNA, lipids, proteins, and metabolites. Exo...

Safety and Efficacy of Intravitreal Risuteganib for Non-Exudative AMD: A Multicenter, Phase 2a, Randomized, Clinical Trial.

Jul 01, 2021

To evaluate the safety and efficacy of 1.0 mg risuteganib in subjects with nonexudative age-related macular degeneration (AMD).This was a phase 2a, prospective, double-masked, sham-controlled study. E...

Comparison of long-term surgical outcomes for scleral-fixated verses retropupillary iris-claw intraocular lens.

Jul 01, 2021

To compare the clinical features and long-term treatment outcomes of patients undergoing secondary intraocular lens (IOL) surgery with scleral-fixated (SFIOL) versus retropupillary iris-claw IOL (RPIC...

Trabeculectomy with Mitomycin-C in Post-Traumatic Angle Recession Glaucoma in Phakic Eyes With no Prior Intraocular Intervention.

Jul 01, 2021

: To evaluate the outcomes of primary trabeculectomy with mitomycin-C (trab MMC) in phakic eyes with post-traumatic angle recession glaucoma with no prior intraocular surgeries.: We included 32 phakic...

Outcomes of Management of Glaucoma in Phacomatosis Pigmentovascularis over the last three decades: a single-center experience.

Jul 01, 2021

To report the clinical outcomes of glaucoma management in patients with phacomatosis pigmentovascularis (PPV) treated over a period of three decades.Retrospective cohort study.Fifty-five eyes of 38 pa...

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