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Ophthalmology General

Functional integration of eye tissues and refractive eye development: Mechanisms and pathways.

Jul 08, 2021

Refractive eye development is a tightly coordinated developmental process. The general layout of the eye and its various components are established during embryonic development, which involves a compl...

Online Vs In-person Education: Evaluating the Potential Influence of Teaching Modality on Dry Eye Symptoms and Risk Factors During the COVID-19 Pandemic.

Jul 08, 2021

To assess the potential effects of switching to online lecture format on dry eye symptoms and dry eye disease (DED) risk factors.An anonymous cross-sectional online survey was conducted in 812 univers...

Meibomian Gland Dysfunction and Lipid Profile: A Study Among Pregnant Women.

Jul 08, 2021

This study aimed to estimate the frequency of meibomian gland dysfunction (MGD) and its associated factors among pregnant women.This was a hospital-based cross-sectional study of consecutive pregnant ...

Commercially Available Eye Drops Containing Trehalose Protect Against Dry Conditions via Autophagy Induction.

Jul 08, 2021

Evaluation of marketed eye drops with or without trehalose, a nonreducing natural osmoprotector disaccharide, in autophagy modulation and its role in cell survival during desiccation. Eye drops cont...

Urinary proteome and diabetic retinopathy in the DIRECT-Protect 1 and 2 trials.

Jul 08, 2021

Given the association of diabetic retinopathy (DR) and kidney disease, we investigated the urinary proteome to presence and deterioration of DR in a post hoc analysis of trials investigating the effec...

Mfsd2a overexpression alleviates vascular dysfunction in diabetic retinopathy.

Jul 08, 2021

Diabetic retinopathy (DR) is one of the common complications in diabetic patients. Nowadays, VEGF pathway is subject to extensive research. However, about 27% of the patients have a poor visual outcom...

Identification of connexin43 in diabetic retinopathy and its downregulation by O-GlcNAcylation to inhibit the activation of glial cells.

Jul 08, 2021

Despite advances in the treatments of diabetic complications, proliferative diabetic retinopathy (PDR) still remains a major cause leading to visual loss, mainly because of the lack of pathological me...

[Intraocular pressure elevation after vitrectomy-Goldmann applanation tonometry measures lower intraocular pressure than dynamic contour tonometry].

Jul 08, 2021

The dynamic contour tonometer PASCAL (DCT) is a direct noninvasive digital tonometer matching the corneal contour. We compared the DCT with the Goldmann applanation tonometer (GAT).A total of 100 eye...

Prostanoid receptor agonists for glaucoma treatment.

Jul 08, 2021

Intraocular pressure reduction is the only available and evidence-based medical therapy for glaucoma. Currently, the first-line eye drops are prostaglandin analogues including latanoprost, travoprost,...

Edward S Perkins, MD, PhD (1919-2015): In the vanguard of ophthalmic physician-scientists.

Jul 08, 2021

British-American ophthalmologist Edward Perkins, MD, PhD (1919-2015) held wide-ranging research interests during his career at the Institute of Ophthalmology in London, the University of Iowa, and as ...

Five-year review of ocular Neisseria gonorrhoeae infections presenting to ophthalmology departments in Greater Glasgow & Clyde, Scotland.

Jul 08, 2021

As gonococcal infections continue to increase, we wanted to review the number and clinical course of recent ocular gonococcal cases presenting to ophthalmology departments in NHS Greater Glasgow and C...

Resident Participation and Patient Outcomes in Vitreoretinal Surgery.

Jul 08, 2021

This prospective, observational cohort study of 116 patients found that residents could participate in ∼40% of vitreoretinal surgery cases with good visual and anatomical outcomes. Ophthalmology res...

Proteome characterization of glaucoma aqueous humour.

Jul 05, 2021

Glaucoma is the leading cause of irreversible blindness worldwide. The proteome characterization of glaucoma is not clearly understood. A total of 175 subjects, including 57 primary acute angle-closur...

Distribution and determinants of hospital efficiency and relative productivity in county-level hospitals in rural China: an observational study.

Jul 05, 2021

Cataract surgery is very important to prevent blindness, but its productivity and efficiency in China are unknown. Our study aimed to evaluate the geographical distribution of cataract surgeons and pr...

Retinal Stem Cell 'Retirement Plans': Growth, Regulation and Species Adaptations in the Retinal Ciliary Marginal Zone.

Jul 05, 2021

The vertebrate retina develops from a specified group of precursor cells that adopt distinct identities and generate lineages of either the neural retina, retinal pigmented epithelium, or ciliary body...

Nitric Oxide Interaction with the Eye.

Jul 05, 2021

Nitric oxide (NO) is acknowledged as a vital intercellular messenger in multiple systems in the body. Medicine has focused on its functions and therapeutic applications for decades, especially in card...

Real-World Anti-Vascular Endothelial Growth Factor Therapy Outcomes in Myopic Choroidal Neovascularization.

Jul 05, 2021

Evaluation of real-world outcomes of intravitreal anti-vascular endothelial growth factor (anti-VEGF) therapy in the primary treatment of choroidal neovascularization (CNV) secondary to pathological m...

Autologous serum compared to artificial tear drops for dry eye disease.

Jul 05, 2021

Dry eye is one of the most common ocular surface disorders. Although artificial tear drops therapy is the most widely used treatment, it has recently been suggested that autologous serum could be a be...

Fecal Microbial Transplant in Individuals with Immune-mediated Dry Eye.

Jul 05, 2021

To evaluate the safety of Fecal Microbial Transplant (FMT) in individuals with immune-mediated dry eye (DE).Open-label, non-randomized clinical trial.Ten individuals with DE symptoms and signs meeting...

Sjögren's syndrome in children: about 15 cases in Guinea Conakry.

Jul 05, 2021

Sjögren's syndrome is rare in children and most often secondary. It frequently affects girls and is characterized by dry eye syndrome, mouth and sometimes systemic involvement. Its diagnosis is diffi...

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