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Ophthalmology General

Toric Intraocular Lens Calculation considering anterior Surgically Induced Astigmatism and Posterior Corneal Astigmatism.

Jun 28, 2021

to evaluate the prediction error (PE) after applying the Abulafia-Koch formula in an online calculator with and without consideration of anterior corneal surgically induced astigmatism (SIA).SIA model...

Ocular Surface Changes in Patients with Thyroid Eye Disease: An Observational Clinical Study.

Jun 28, 2021

This study aimed to compare ocular surface parameter changes in active and inactive thyroid eye disease (TED) patients and controls.This is an observational clinical study that included 60 eyes divide...

Effects of Topical Gabapentin on Ocular Pain and Tear Secretion.

Jun 28, 2021

Neuropathic ocular pain is a frequent occurrence in medium to severe dry eye disease (DED). Only palliative treatments, such as lubricants and anti-inflammatory drugs, are available to alleviate patie...

The effects of caffeic acid phenethyl ester on retina in a diabetic rat model.

Jun 28, 2021

We aimed to investigate the effect of caffeic acid phenethyl ester (CAPE) on retinal apoptosis and oxidative stress parameters in streptozotocin (STZ) induced diabetic rat model.This study included 3 ...

Gene Set Enrichment Analyses Identify Pathways Involved in Genetic Risk for Diabetic Retinopathy.

Jun 28, 2021

To identify functionally related genes associated with diabetic retinopathy (DR) risk using gene set enrichment analyses (GSEA) applied to genome-wide association study (GWAS) meta-analyses.We analyze...

Development and Validation of a Preference-Based Glaucoma Utility Instrument Using Discrete Choice Experiment.

Jun 28, 2021

A glaucoma-specific instrument for estimating utilities across the spectrum of glaucoma severity is currently lacking, hindering the assessment of the cost-effectiveness of glaucoma treatments.To deve...

Thiazide and other Cl-benzenesulfonamide-bearing clinical drug affinities for human carbonic anhydrases.

Jun 28, 2021

Twelve carbonic anhydrase (CA) isoforms catalyze carbon dioxide hydration to bicarbonate and acid protons and are responsible for many biological functions in human body. Despite their vital functions...

Active Rap1-mediated inhibition of choroidal neovascularization requires interactions with IQGAP1 in choroidal endothelial cells.

Jun 28, 2021

Neovascular age-related macular degeneration (nAMD) is a leading cause of blindness. The pathophysiology involves activation of choroidal endothelial cells (CECs) to transmigrate the retinal pigment e...

A Community Based Cross Sectional Study to Estimate the Prevalence and Associated Factors of Hypertension in Rural Nepal.

Jun 24, 2021

Background Hypertension is a major global public health problem because of its high prevalence as it significantly increases the risk of heart attack, stroke, kidney failure and blindness. Epidemiolog...

High irisin and low BDNF levels in aqueous humor of high myopia.

Jun 24, 2021

The pathogenesis of myopia remains unclear. Both genetic and environmental factors play a role in the disease progression. Reasons including reduced physical activity (PA) and low-grade intraocular in...

Acute Attack of Primary Angle Closure in a Highly Axially Myopic Eye: A Case Report.

Jun 24, 2021

BACKGROUND Primary angle closure (PAC) is common in hyperopic eyes, but it is rarely observed in highly myopic eyes. Myopic eyes have a longer axial length and a deeper anterior chamber compared with ...

[COMPUTER VISION SYNDROME].

Jun 24, 2021

Computer vision syndrome (CVS) is a very common phenomenon amongst computer users. A total of 90% of computer users, who spend more than 3 hours a day in front of the computer screen, suffer from CVS....

The clinical effects of sodium hyaluronate, polyethylene glycol, and dextran-70 eye drops in relieving dry eye after phacoemulsification.

Jun 24, 2021

To compare the clinical efficacy of sodium hyaluronate eye drops, polyethylene glycol eye drops, and compound dextran eye drops in the treatment of dry eye after phacoemulsification of cataract.A tota...

ACE2 Expression Is Upregulated in Inflammatory Corneal Epithelial Cells and Attenuated by Resveratrol.

Jun 24, 2021

The ocular surface is considered an important route for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) transmission. The expression level of the SARS-CoV-2 receptor angiotensin-convertin...

Vision, Eye Disease, and the Onset of Balance Problems: The Canadian Longitudinal Study on Aging: Vision and Balance Problems.

Jun 24, 2021

To understand the relationship between visual impairment, self-reported eye disease, and the onset of balance problems.Population-based prospective cohort study METHODS: : Baseline and 3-year follow-u...

Association of periodontitis and diabetic macular edema in various stages of diabetic retinopathy.

Jun 24, 2021

Periodontitis and diabetes are known to have a bidirectional relationship. Diabetic macular edema is a complication of diabetes that is strongly influenced by inflammatory pathways. However, it remain...

Retinal arteriolar tortuosity and fractal dimension are associated with long-term cardiovascular outcomes in people with type 2 diabetes.

Jun 24, 2021

Our aim was to determine whether quantitative retinal traits in people with type 2 diabetes are independently associated with incident major cardiovascular events including CHD and stroke.A total of 1...

Ocular Toxoplasmosis among Livestock Farmers and Raw Meat Handlers in Uyo, Nigeria.

Jun 24, 2021

Toxoplasmosis is the commonest cause of infectious posterior uveitis in humans and can lead to blindness and low vision in both immune-competent and immunecompromised persons worldwide. The aim of thi...

The association between hormonal contraceptive use and glaucoma in women of reproductive age.

Jun 24, 2021

We aimed to investigate the association between hormonal contraceptive (HC) use and the incidence of glaucoma in females of reproductive age with a focus on duration and type of HCs used.A retrospecti...

Cell-based therapy for ocular disorders: A promising frontier.

Jun 24, 2021

As the ocular disorders causing long-term blindness or optical abnormalities of the ocular tissue affect the quality of life of patients to a large extent, awareness of their corresponding pathogenesi...

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