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Ophthalmology General

Searching for the Antioxidant, Anti-Inflammatory, and Neuroprotective Potential of Natural Food and Nutritional Supplements for Ocular Health in the Mediterranean Population.

Jun 03, 2021

Adherence to a healthy diet offers a valuable intervention to compete against the increasing cases of ocular diseases worldwide, such as dry eye disorders, myopia progression, cataracts, glaucoma, dia...

Comparison of the Safety and Efficacy between Preserved and Preservative-Free Latanoprost and Preservative-Free Tafluprost.

Jun 03, 2021

In this study, we investigated the effect of preservative-free (PF) 0.0015% tafluprost (TA), to the preservative containing (PC) and the PF 0.005% latanoprost (LA) in Korean subjects. This study was c...

Reliability and efficacy of maximum fluorescein tear break-up time in diagnosing dry eye disease.

Jun 03, 2021

This study aims to investigate the reliability and efficacy of maximum fluorescein tear break-up time (FTBUTmax) in diagnosing dry eye disease (DED). 147 participants were enrolled in this study. Ocul...

Risk factors for posterior capsule rupture in cataract surgery as reflected in the European Registry of Quality Outcomes for Cataract and Refractive Surgery.

Jun 03, 2021

To analyze the incidence and risk factors of posterior capsule rupture (PCR) in cataract surgery.European clinics affiliated with the European Registry of Quality Outcomes for Cataract and Refractive ...

Sulodexide reduces glucose induced senescence in human retinal endothelial cells.

Jun 03, 2021

Chronic exposure of retinal endothelium cells to hyperglycemia is the leading cause of diabetic retinopathy. We evaluated the effect of high glucose concentration on senescence in human retinal endoth...

2-Year Real-World Outcomes with Intravitreal Aflibercept in Neovascular Age-Related Macular Degeneration: Literature Review and Meta-analysis of Patient-Relevant Outcomes.

Jun 03, 2021

The 96 weeks' assessment from the VIEW studies provided insights into the long-term efficacy of intravitreal aflibercept (IVT-AFL) in neovascular age-related macular degeneration (nAMD) and demonstra...

Pretreatment with frequent topical betamethasone in Ahmed glaucoma valve implantation.

Jun 03, 2021

To evaluate the efficacy of pretreatment with topical betamethasone in Ahmed glaucoma valve (AGV) implantation.Randomized clinical trial.Sixty-two eyes from 62 patients undergoing AGV.We randomly assi...

Large-scale machine learning-based phenotyping significantly improves genomic discovery for optic nerve head morphology.

Jun 03, 2021

Genome-wide association studies (GWASs) require accurate cohort phenotyping, but expert labeling can be costly, time intensive, and variable. Here, we develop a machine learning (ML) model to predict ...

Automated AI labeling of optic nerve head enables insights into cross-ancestry glaucoma risk and genetic discovery in >280,000 images from UKB and CLSA.

Jun 03, 2021

Cupping of the optic nerve head, a highly heritable trait, is a hallmark of glaucomatous optic neuropathy. Two key parameters are vertical cup-to-disc ratio (VCDR) and vertical disc diameter (VDD). Ho...

AUTHENTIC RESEARCH IN THE CLASSROOM INCREASES APPRECIATION FOR PLANTS IN UNDERGRADUATE BIOLOGY STUDENTS.

May 31, 2021

Engaging students in authentic research increases student knowledge, develops STEM skills, such as data analysis and scientific communication, and builds community. Creating authentic research opportu...

Risk Factors for Corneal Striae in Eyes after Glaucoma Surgery.

May 31, 2021

Eyes with corneal striae had steeper cornea, induced astigmatism, and higher corneal hysteresis, which implies a relationship between striae, corneal shape, and the cornea's resistance to deformation ...

Intraocular epidermal growth factor concentration, axial length, and high axial myopia.

May 31, 2021

Various molecules such as dopamine have been found to be associated with axial elongation in experimental studies. Here, we examined whether intraocular EGF is associated with axial length in myopic p...

A multicenter clinical trial of orthokeratology in school-aged children and adolescents in Japan.

May 31, 2021

This study investigated the safety and efficacy of orthokeratology in myopic children in Japan.Prospective clinical trial.This study enrolled myopic children aged 6-16 years with a spherical equivale...

Impact of virtual reality headset use on eye blinking and lipid layer thickness.

May 31, 2021

Blinking plays an important role in protecting the eyes, and the use of computers has been associated with a reduction in the blink rate. The goal of this study was to evaluate the effect of a virtual...

Combined Intense Pulsed Light and Low-Level Light Therapy for the Treatment of Dry Eye: A Retrospective Before-After Study with One-Year Follow-Up.

May 31, 2021

To assess the effectiveness of a combination of intense pulsed light and low-level light therapy (IPL/LLLT) for the treatment of dry eye.Retrospective before-after single-center clinical study.Patient...

Proteoglycan 4 (PRG4) expression and function in dry eye associated inflammation.

May 31, 2021

Dry eye disease (DED) affects hundreds of millions of people worldwide. It is characterized by the production of inflammatory cytokines and chemokines as well as damaging matrix metalloproteinases (MM...

Efficacy of calcium dobesilate in treating Chinese patients with mild-to-moderate non-proliferative diabetic retinopathy (CALM-DR): protocol for a single-blind, multicentre, 24-armed cluster-randomised, controlled trial.

May 31, 2021

Calcium dobesilate (CaD) has been used in the treatment of diabetic retinopathy (DR) due to its potential in protecting against retinal vascular damage. However, there is limited evidence exploring it...

A deep learning system for detecting diabetic retinopathy across the disease spectrum.

May 31, 2021

Retinal screening contributes to early detection of diabetic retinopathy and timely treatment. To facilitate the screening process, we develop a deep learning system, named DeepDR, that can detect ear...

Analysis of progressive neovascularization in diabetic retinopathy using widefield optical coherence tomography angiography.

May 31, 2021

To quantitatively and morphologically document enlarged neovascularization elsewhere (NVE) using widefield swept-source (SS) optical coherence tomography angiography (OCTA) with vitreoretinal interfac...

Ab-externo MicroShunt versus Trabeculectomy in Primary Open-Angle Glaucoma: 1-year Results from a 2-year Randomized, Multicenter Study.

May 31, 2021

To compare the effectiveness and safety of the MicroShunt versus trabeculectomy in patients with primary open-angle glaucoma (POAG).One-year results from a 2-year, prospective, randomized, multicenter...

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