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Ophthalmology General

Arbutin inhibits inflammation and apoptosis by enhancing autophagy via SIRT1.

May 13, 2021

SIRT1 plays a protective role against diabetic retinopathy as it regulates inflammation, apoptosis and autophagy of cells.This study was designed to investigate the effects of arbutin and to identify ...

Presumed cytomegalovirus retinitis late after kidney transplant.

May 13, 2021

Cytomegalovirus (CMV) retinitis is a rare manifestation of CMV invasive disease and potentially threatening to vision in immunocompromised individuals. Clinical suspicion is fundamental since it is an...

Identification of peripheral anterior synechia with anterior segment optical coherence tomography.

May 13, 2021

To generate a model that evaluates the presence and extent of peripheral anterior synechia (PAS) based on anterior segment optical coherence tomography (AS-OCT).The extent of PAS involvement in the ey...

Searching for emotional salience.

May 13, 2021

In the emotion induced blindness (EIB) paradigm, participants search for a single target picture embedded in a rapidly presented sequence of "background" pictures. When the sequence also contains a ta...

Modeling the impact of COVID-19 on Retina Clinic Performance.

May 13, 2021

COVID-19, a highly contagious respiratory virus, presents unique challenges to ophthalmology practice as a high-volume, office-based specialty. In response to the COVID-19 pandemic, many operational c...

Melatonin prevents blood-retinal barrier breakdown and mitochondrial dysfunction in high glucose and hypoxia-induced in vitro diabetic macular edema model.

May 10, 2021

Diabetic macular edema (DME) is a leading cause of blindness in diabetic retinopathy. Prolonged hyperglycemia plus hypoxia contributes to DME pathogenesis. Retinal pigmented epithelial cells comprise ...

Elevated dimethylarginine, ATP, cytokines, metabolic remodeling involving tryptophan metabolism and potential microglial inflammation characterize primary open angle glaucoma.

May 10, 2021

Glaucoma of which primary open angle glaucoma (POAG) constitutes 75%, is the second leading cause of blindness. Elevated intra ocular pressure and Nitric oxide synthase (NOS) dysfunction are hallmarks...

The Risks and Benefits of Myopia Control.

May 10, 2021

The prevalence of myopia is increasing around the world, stimulating interest in methods to slow its progression. The primary justification for slowing myopia progression is to reduce the risk of visi...

Prediction of postoperative refractive astigmatism before toric intraocular lens implantation.

May 10, 2021

To determine the preoperative factors influencing refractive astigmatism after cataract surgery for astigmatism correction by toric intraocular lens (IOL) implantation and to evaluate the prediction m...

Quantitative proteomic analysis of scleras in guinea pig exposed to wavelength defocus.

May 10, 2021

Myopia is the most common optical disorder in the world, and wavelength defocus induced ametropia and myopia have attracted great attention. The objective was to identify and quantify scleral proteins...

Trehalose/sodium hyaluronate eye drops in post-cataract ocular surface disorders.

May 10, 2021

Prospective, randomised, open-label, comparative study to evaluate efficacy of trehalose/sodium hyaluronate eye drops for post-operative discomfort and tear film stability in patients undergoing catar...

Ophthalmologic findings and complications before and after hematopoietic stem cell transplantation: single-center study.

May 10, 2021

Different and various system complications and late effects may occur after hematopoietic stem cell transplantation (HSCT). It was aimed to obtain information about the frequency of ophthalmologic com...

Clinical practice patterns in the management of dry eye disease: A TFOS international survey.

May 10, 2021

To examine clinical management and prescribing patterns for dry eye disease (DED), in relation to severity and subtype, by eyecare practitioners across the globe.An online-anonymous cross-sectional su...

Obesity and risk of age-related eye diseases: a systematic review of prospective population-based studies.

May 10, 2021

Obesity is a public health challenge worldwide. The relationship between obesity and age-related eye diseases including cataract, glaucoma, age-related macular degeneration (AMD) and diabetic retinopa...

Remnant cholesterol predicts progression of diabetic nephropathy and retinopathy in type 1 diabetes.

May 10, 2021

We aimed to assess whether remnant cholesterol concentration and variability predict the progression of diabetic nephropathy (DN) and severe diabetic retinopathy (SDR) in type 1 diabetes.This observat...

Amelioration of diabetic retinopathy in db/db mice by treatment with different proportional three active ingredients from Tibetan medicine Berberis dictyophylla F.

May 10, 2021

Berberis dictyophylla F., a famous Tibetan medicine, has been used to prevent and treat diabetic retinopathy (DR) for thousands of years in clinic. However, its underlying mechanisms remain unclear.Th...

Inter-eye relationship of intraocular pressure change after unilateral trabeculectomy, filtering canaloplasty, or PreserFlo™ microshunt implantation.

May 10, 2021

This study assesses short-term intraocular pressure (IOP) change in the fellow eye of glaucoma patients after mitomycin C-augmented trabeculectomy, filtering canaloplasty, or PreserFlo™ microsh...

Joint optic disc and optic cup segmentation based on boundary prior and adversarial learning.

May 10, 2021

The most direct means of glaucoma screening is to use cup-to-disc ratio via colour fundus photography, the first step of which is the precise segmentation of the optic cup (OC) and optic disc (OD). In...

New Compound Heterozygous CYP4V2 Mutations in Bietti Crystalline Corneoretinal Dystrophy.

May 10, 2021

Bietti crystalline corneoretinal dystrophy (BCD) is an autosomal recessive retinal dystrophy which is caused by the mutations of CYP4V2, usually progressing to legal blindness by the 5th or 6th decade...

Patient and Resource Management of Emergency Walk-In Clinic During a COVID-19 Pandemic State Lockdown.

May 10, 2021

To gather data on the most common chief complaints, diagnoses, in-office procedures, and surgeries that presented to the Kresge Eye Institute's Emergency Clinic in Detroit, Michigan during the COVID-1...

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