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Ophthalmology General

Subthreshold Nanosecond Laser, from Trials to Real-Life Clinical Practice: A Cohort Study.

May 17, 2021

Age-related macular degeneration (AMD), a degenerative disorder, is a major cause of irreversible severe visual deterioration in the older Western population. Thus, treatments that resolve drusen may ...

Molecular genetics with clinical characteristics of Leber congenital amaurosis in the Han population of western China.

May 13, 2021

: Leber congenital amaurosis (LCA) is one of the earliest inherited retinal dystrophies (IRD) that leads to blindness. To date, there have been 25 LCA-associated genes reported in China as well as oth...

Ocular Anatomical and Functional Characteristics in Anisometropic Chinese Children.

May 13, 2021

This research found that anterior and posterior biometrics differ in many aspects between fellow eyes of anisometropic children. This might shed light on the mechanisms underlying the onset and progre...

Comparison of corneal surgically induced astigmatism calculations as measured by two biometric devices, and by standard anterior vs total keratometric measurements.

May 13, 2021

To compare calculated corneal surgically induced astigmatism (SIA) by means of anterior-based keratometry (K) and total keratometry (TK) measurements made by 2 biometric devices.Ophthalmology Departme...

Compression Factor and Visual Performance in Adults Treated With Orthokeratology.

May 13, 2021

To investigate the effect of compression factor on visual performance in orthokeratology (ortho-k).Myopic adults were fitted with ortho-k lenses with either a 0.75 diopter (D) or 1.75 D compression fa...

A spectroscopic study of the composition and conformation of cholesteryl and wax esters purified from meibum.

May 13, 2021

Elucidating wax ester (WE) and cholesteryl ester (CE) compositional, structural and functional relationships is key to our understanding of how these lipids are involved in natural and pathological pr...

Demographic and lifestyle risk factors of dry eye disease subtypes: A cross-sectional study.

May 13, 2021

To evaluate demographic and lifestyle factors associated with aqueous deficient and evaporative dry eye disease.A total of 1125 general public visitors (707 females, mean ± SD age, 33 ± 21, ...

Ocular Manifestations and Neuropathy in Type 2 Diabetes Patients With Charcot Arthropathy.

May 13, 2021

Diabetes can affect the eye in many ways beyond retinopathy. This study sought to evaluate ocular disease and determine any associations with peripheral neuropathy (PN) or cardiac autonomic neuropathy...

Capturing the clinical decision-making processes of expert and novice diabetic retinal graders using a 'think-aloud' approach.

May 13, 2021

Diabetic eye screening programmes have been developed worldwide based on evidence that early detection and treatment of diabetic retinopathy are crucial to preventing sight loss. However, little is kn...

Arbutin inhibits inflammation and apoptosis by enhancing autophagy via SIRT1.

May 13, 2021

SIRT1 plays a protective role against diabetic retinopathy as it regulates inflammation, apoptosis and autophagy of cells.This study was designed to investigate the effects of arbutin and to identify ...

Presumed cytomegalovirus retinitis late after kidney transplant.

May 13, 2021

Cytomegalovirus (CMV) retinitis is a rare manifestation of CMV invasive disease and potentially threatening to vision in immunocompromised individuals. Clinical suspicion is fundamental since it is an...

Identification of peripheral anterior synechia with anterior segment optical coherence tomography.

May 13, 2021

To generate a model that evaluates the presence and extent of peripheral anterior synechia (PAS) based on anterior segment optical coherence tomography (AS-OCT).The extent of PAS involvement in the ey...

Searching for emotional salience.

May 13, 2021

In the emotion induced blindness (EIB) paradigm, participants search for a single target picture embedded in a rapidly presented sequence of "background" pictures. When the sequence also contains a ta...

Modeling the impact of COVID-19 on Retina Clinic Performance.

May 13, 2021

COVID-19, a highly contagious respiratory virus, presents unique challenges to ophthalmology practice as a high-volume, office-based specialty. In response to the COVID-19 pandemic, many operational c...

Melatonin prevents blood-retinal barrier breakdown and mitochondrial dysfunction in high glucose and hypoxia-induced in vitro diabetic macular edema model.

May 10, 2021

Diabetic macular edema (DME) is a leading cause of blindness in diabetic retinopathy. Prolonged hyperglycemia plus hypoxia contributes to DME pathogenesis. Retinal pigmented epithelial cells comprise ...

Elevated dimethylarginine, ATP, cytokines, metabolic remodeling involving tryptophan metabolism and potential microglial inflammation characterize primary open angle glaucoma.

May 10, 2021

Glaucoma of which primary open angle glaucoma (POAG) constitutes 75%, is the second leading cause of blindness. Elevated intra ocular pressure and Nitric oxide synthase (NOS) dysfunction are hallmarks...

The Risks and Benefits of Myopia Control.

May 10, 2021

The prevalence of myopia is increasing around the world, stimulating interest in methods to slow its progression. The primary justification for slowing myopia progression is to reduce the risk of visi...

Prediction of postoperative refractive astigmatism before toric intraocular lens implantation.

May 10, 2021

To determine the preoperative factors influencing refractive astigmatism after cataract surgery for astigmatism correction by toric intraocular lens (IOL) implantation and to evaluate the prediction m...

Quantitative proteomic analysis of scleras in guinea pig exposed to wavelength defocus.

May 10, 2021

Myopia is the most common optical disorder in the world, and wavelength defocus induced ametropia and myopia have attracted great attention. The objective was to identify and quantify scleral proteins...

Trehalose/sodium hyaluronate eye drops in post-cataract ocular surface disorders.

May 10, 2021

Prospective, randomised, open-label, comparative study to evaluate efficacy of trehalose/sodium hyaluronate eye drops for post-operative discomfort and tear film stability in patients undergoing catar...

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