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Ophthalmology General

Computerised dynamic posturography for postural control assessment in subjects wearing multifocal contact lenses dedicated for myopia control.

May 03, 2021

To measure body balance using computerised dynamic posturography in young adults wearing multifocal contact lenses (MFCL) with high addition powers designed for myopia control.Twenty-four young adults...

Optimization of goblet cell density quantification methods.

May 03, 2021

The purpose of this study was to develop a standardized, accurate and efficient method for estimating conjunctival goblet cell density (GCD) via optimizing sample storage conditions and quantification...

Inducing dry eye disease using a custom engineered desiccation system: Impact on the ocular surface including keratin-14-positive limbal epithelial stem cells.

May 03, 2021

Dry eye disease (DED) is characterized by loss of tear film stability that becomes self-sustaining in a vicious cycle of pathophysiological events. Currently, desiccation stress (DS) is the dominant p...

Neuropathic corneal pain and dry eye: a continuum of nociception.

May 03, 2021

Throughout the body, damage to peripheral nerves normally involved in nociception may produce a constellation of symptoms-including irritation, itchiness and pain. The neurobiological processes involv...

Neurovascular unit in diabetic retinopathy: pathophysiological roles and potential therapeutical targets.

May 03, 2021

Diabetic retinopathy (DR), one of the common complications of diabetes, is the leading cause of visual loss in working-age individuals in many industrialized countries. It has been traditionally regar...

Plasma miR-26a-5p is a biomarker for retinal neurodegeneration of early diabetic retinopathy.

May 03, 2021

Retinal neurodegeneration is an early pathological change in diabetic retinopathy (DR). Early-stage retinal neurodegeneration is usually asymptomatic. This study aims to identify circulating microRNAs...

Simultaneous determination of six main components in Bushen Huoxue prescription by HPLC-CAD.

May 03, 2021

The Bushen Huoxue prescription is a traditional Chinese medicine formula treating diabetic retinopathy, which was developed by our research group. Catalpol, puerarin, salvianolic acid B, ginsenoside R...

[Micropulse cyclophotocoagulation lowers the intraocular pressure: half year results].

May 03, 2021

Cyclophotocoagulation (CPC) is a simple noninvasive and quickly available procedure for lowering intraocular pressure but due to its dreaded potential for complications it continues to play an outsid...

[Screening for retinopathy of prematurity-the most important changes in the new German guidelines 2020].

May 03, 2021

Due to improvements in neonatal care of premature infants and the development of novel treatment options for retinopathy of prematurity (ROP), the requirements for screening for ROP have changed since...

Naturalistic Driving Techniques and Association of Visual Risk Factors With At-Fault Crashes and Near Crashes by Older Drivers With Vision Impairment.

May 03, 2021

Government motor vehicle crash reports used in the study of driver safety can be biased and incomplete. Naturalistic driving methods using in-vehicle instrumentation have been developed in recent year...

Evaluation of the Manchester COVID-19 Urgent Eyecare Service (CUES).

May 03, 2021

Pressure on capacity in ophthalmology alongside the coronavirus (COVID-19) pandemic led to the development of the COVID-19 Urgent Eyecare Service (CUES), allowing patients to receive a prompt ophthalm...

The retinal pigment epithelium: Development, injury responses, and regenerative potential in mammalian and non-mammalian systems.

Apr 29, 2021

Diseases that result in retinal pigment epithelium (RPE) degeneration, such as age-related macular degeneration (AMD), are among the leading causes of blindness worldwide. Atrophic (dry) AMD is the mo...

Discovery of Novel Small-Molecule Antiangiogenesis Agents to Treat Diabetic Retinopathy.

Apr 29, 2021

Diabetic retinopathy is the leading cause of blindness which is associated with excessive angiogenesis. Using the structure of wondonin marine natural products, we previously created a scaffold to dev...

Automatic identification of myopic maculopathy related imaging features in optic disc region via machine learning methods.

Apr 29, 2021

Myopic maculopathy (MM) is the most serious and irreversible complication of pathologic myopia, which is a major cause of visual impairment and blindness. Clinic proposed limited number of factors rel...

Elongation of the disc-fovea distance and retinal vessel straightening in high myopia in a 10-year follow-up of the Beijing eye study.

Apr 29, 2021

To assess changes in the disc-fovea distance (DFD) in highly myopic eyes in a 10-year population-based follow-up study. The case control study included all highly myopic eyes (myopic refractive errorâ...

Carbon quantum dots as a dual platform for the inhibition and light-based destruction of collagen fibers: implications for the treatment of eye floaters.

Apr 29, 2021

Common in myopia and aging, vitreous opacities arise from clumped collagen fibers within the vitreous body that cast shadows on the retina, appearing as 'floaters' to the patient. Vitreous opacities d...

Gene therapy in the anterior eye segment.

Apr 29, 2021

This review provides comprehensive information about the advances in gene therapy in the anterior segment of the eye including cornea, conjunctiva, lacrimal gland, and trabecular meshwork. We discuss ...

Laser Acupuncture Improves Tear Film Stability in Patients with Dry Eye Disease: A Two-Center Randomized-Controlled Trial.

Apr 29, 2021

To investigate the efficacy of laser acupuncture (LA) therapy in patients with dry eye disease (DED). A two-center randomized controlled trial. The Department of Ophthalmology, Chinese Medicine at ...

Comparison of the effect of Tea tree oil shampoo with regular-lid shampoo in meibomian gland dysfunction treatment.

Apr 29, 2021

This study is aimed at comparing the effects of Tea Tree Oil shampoo (TTO) with regular-lid shampoo on the treatment of meibomian gland dysfunction (MGD) signs and symptoms.Double-masked randomized cl...

Testing the performance of risk prediction models to determine progression to referable diabetic retinopathy in an Irish type 2 diabetes cohort.

Apr 29, 2021

To evaluate the performance of existing prediction models to determine risk of progression to referable diabetic retinopathy (RDR) using data from a prospective Irish cohort of people with type 2 diab...

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