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Ophthalmology General

Altered ocular surface immune cell profile in patients with dry eye disease.

Apr 19, 2021

Aberrant inflammation and immune dysregulation are known pathogenic contributors in dry eye disease (DED). Aim of the study was to determine the proportions of immune cell subsets on the ocular surfac...

Amniotic membrane extract eye drops for ocular surface diseases: use and clinical outcome in real-world practice.

Apr 19, 2021

To study the indications and clinical outcomes, in a real-word setting, of amniotic membrane extract eye drops (AMEED) use for ocular surface disease (OSD).A retrospective study of patients treated wi...

Temporal evolution of the biological response to laser-induced refractive index change (LIRIC) in rabbit corneas.

Apr 19, 2021

Laser induced refractive index change (LIRIC) is a new, non-incisional, non-ablative, femtosecond photo-modification technique being developed for vision correction in humans. Prior, ex-vivo studies s...

Eye pain and blurred vision as main complaints in a new case with MDPL syndrome.

Apr 19, 2021

We report a novel phenotype of mandibular hypoplasia, deafness, and progeroid features with lipodystrophy (MDPL) syndrome with mutation in a Chinese girl.Diabetic retinopathy was detected as the prim...

Ophthalmology Services at Student-Run Free Clinics: A National Survey.

Apr 19, 2021

Student-run free clinics (SRFCs) primarily service the uninsured and are a unique way for medical students to gain hands-on exposure to ophthalmology. The free clinic model takes many different forms-...

Diabetic retinopathy, oxidative stress and sirtuins: an in depth look in enzymatic patterns and new therapeutic horizons.

Apr 19, 2021

Diabetic retinopathy (DR) is one of the leading causes of blindness in the world. DR represents the most common microvascular complication of diabetes, and its incidence is constantly rising. The comp...

Corneal Biomechanical Assessment with Ultra-High-Speed Scheimpflug Imaging During Non-Contact Tonometry: A Prospective Review.

Apr 19, 2021

In recent years, increasing interest has arisen in the application of data from corneal biomechanics in many areas of ophthalmology, particularly to assist in the detection of early corneal ectasia or...

Making Biological Sense of Genetic Studies of Age-Related Macular Degeneration.

Apr 15, 2021

Age-related macular degeneration (AMD) is a major cause of blindness in older individuals worldwide. The disease is characterized by deposition of drusen between the retinal pigment epithelium (RPE) a...

Cell-Based Therapies for Age-Related Macular Degeneration.

Apr 15, 2021

Age-related macular degeneration (AMD) is a leading cause of blindness worldwide. The pathogenesis of AMD involves dysfunction and loss of the retinal pigment epithelium (RPE), a monolayer of cells th...

Current Management of Age-Related Macular Degeneration.

Apr 15, 2021

Age-related macular degeneration (AMD) remains a leading cause of blindness worldwide. The assessment and management of patients with this condition has evolved in the last decades. In this chapter, c...

Objective evaluation of static and dynamic behavior of different toric silicone-hydrogel contact lenses.

Apr 15, 2021

The present study aimed to estimate how orientation position, recovery time, and contact lens decentration, associated with visual performance, may vary on several designs of the most recent toric sil...

Central and mid-peripheral corneal astigmatism in an elderly population: a retrospective analysis of Scheimpflug topography results.

Apr 15, 2021

Implantation of toric intraocular lenses (IOLs) has become standard in the correction of corneal astigmatism. The IOL selection is based on keratometric measurements of the central cornea. However, mi...

Decreased choroidal and scleral thicknesses in highly myopic eyes with posterior staphyloma.

Apr 15, 2021

In this cross-sectional study, we investigated choroidal thickness (CT) and scleral thickness (ST) in highly myopic eyes and their associations with ocular factors. Patients underwent widefield swept-...

Involvement of Laryngopharyngeal Reflux in Ocular Diseases: A State-of-the-Art Review.

Apr 15, 2021

Laryngopharyngeal reflux-associated symptoms embrace a wide variety of head and neck manifestations. Its participation in eye disorders has recently been postulated, and there is currently no consensu...

Evaluation of Online Information on Complementary and Alternative Treatments for Dry Eye Disease.

Apr 15, 2021

Dry eye disease is a common condition with many complementary and alternative therapies promoted online. Patients may inquire about these therapies, and clinicians should be aware of the existence, sa...

Visual and Ocular Conditions among a Homeless Adult Population of Boston.

Apr 15, 2021

The eye care needs of the homeless population in the United States are not well known. This study elucidates those needs for health care for the homeless programs and eye care practitioners. This info...

[Association between serum CTRP9 levels and diabetic retinopathy in patients with type 2 diabetes mellitus].

Apr 15, 2021

To investigate the relationship between serum C1q tumor necrosis factor-related protein 9 (CTRP9) level and the risk of diabetic retinopathy (DR) in patients with type 2 diabetes mellitus (T2DM).A tot...

Liraglutide-induced structural modulation of the gut microbiota in patients with type 2 diabetes mellitus.

Apr 15, 2021

Accumulating evidence has suggested the importance of gut microbiota in the development of type 2 diabetes mellitus (T2DM). In the present study, 40 patients with T2DM were treated with liraglutide fo...

Supplemental light exposure improves sleep architecture in people with type 2 diabetes.

Apr 15, 2021

People with type 2 diabetes (T2D) suffer from sleep disorders, with the mechanism not clearly understood. In T2D, the light transducing retinal photoreceptors that regulate sleep behaviours are dysfun...

Teleglaucoma Initiative at a Veterans Affairs Hospital: Pilot Safety Data and Early Experience.

Apr 15, 2021

To evaluate the safety, reliability and efficacy of telemedicine in delivering tertiary sub-specialty glaucoma care (herein referred to as teleglaucoma) to the Veteran patient population.Prospective c...

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