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Ophthalmology General

Factors associated with delayed diagnosis of Sjögren's syndrome among members of the Japanese Sjögren's Association for Patients.

Apr 08, 2021

The heterogeneous nature of the signs and symptoms of Sjögren's syndrome (SS) often causes delays in diagnosis. The reasons for these delays have not been investigated in Japan and need to be determi...

Dysbiosis and Implication of the Gut Microbiota in Diabetic Retinopathy.

Apr 08, 2021

The pathogenesis of type 2 diabetes mellitus (T2DM) is commonly associated with altered gut bacteria. However, whether the microbial dysbiosis that exists in human diabetic patients with or without re...

Assessment of quality of life of the patients with diabetic retinopathy using National Eye Institute Visual Functioning Questionnaire (VFQ-25).

Apr 08, 2021

Diabetes affects most of the organs causing macrovascular and microvascular complications. Diabetic retinopathy (DR) results from the prolonged uncontrolled hyperglycemia which causes impairment of vi...

Health system strengthening for vision care in The Gambia.

Apr 08, 2021

According to global estimates, 39 million people are blind and 285 million are at risk of severe vision loss, with a significant portion of this burden in Sub-Saharan Africa. Some African nations like...

Screening for open-angle glaucoma and its effect on blindness.

Apr 08, 2021

To evaluate the effect of population screening on low vision and blindness from open-angle glaucoma.Retrospective cohort study.A very large population based screening for glaucoma was conducted in Mal...

Clinic-based eye disease screening employing non-expert fundus photo-graders at the point of screening: diagnostic validity and yield.

Apr 08, 2021

to determine the diagnostic accuracy of several diagnostic tests for AMD, DR, glaucoma, and cataract, as well as the proportion with eye disease from each of three enrolling clinics.Diagnostic accurac...

Evaluating Awareness and Practices Towards Diabetes and Diabetic Retinopathy in Adult Patients Attending the Eye Clinic in a Tertiary Academic Hospital in Jordan.

Apr 08, 2021

Awareness of diabetes mellitus (DM) and its complications, particularly diabetic retinopathy (DR), is one of the main factors of early detection and improved management. This study aims to assess the ...

Case Report: Successful Management of Refractory Keratomycosis in an Alpaca Using Penetrating Keratoplasty and Combination Antifungal Therapy (Caspofungin 0.5% and Terbinafine 1%).

Apr 05, 2021

Fungal keratitis is a common disease in certain parts of the world and affects several species, including equids, camelids, and homo sapiens, leading to blindness or loss of the eye if the infection i...

Infrared Thermally Enhanced 3-Dimensional Time of Flight Magnetic Resonance Angiography Imaging for the Visualization of the Arteries of the Face.

Apr 05, 2021

The face is known for its extreme variation in vascular anatomy. Furthermore, the rapidly increasing number of filler treatments leads to an increase in severe filler-associated complications (such as...

Humanistic and Economic Burden of Blindness Associated with Retinal Disorders in a Brazilian Sample: A Cross-Sectional Study.

Apr 05, 2021

Vision impairment and blindness have been significantly associated with high medical care expenditures, decrease in health utility, and loss or reduction of productivity. The objective of this study w...

Longitudinal analysis of axial length growth in a German cohort of healthy children and adolescents.

Apr 05, 2021

To generate continuous growth curves for axial length (AL) in German children. We hypothesise that percentile curves of AL can be used as a predictive measure of myopia.In this longitudinal and cross-...

Astragalus Ⅳ ameliorates the dry eye injury in rabbit model via MUC1-ErbB1 pathway.

Apr 05, 2021

The therapeutic effects and potential mechanisms of astragaloside IV on a rabbits dry eye model induced by benzalkonium chloride (BAC) was examined. In our study, a BAC-induced dry eye rabbit model wa...

The Enduring Experience in Dry Eye Diagnosis: A Non-Interventional Study Comparing the Experiences of Patients Living With and Without Sjögren's Syndrome.

Apr 05, 2021

Previous studies have examined the patient experience regarding the diagnosis and management of dry eye disease (DED). The current study explored the ways in which the DED diagnostic pathway differs f...

Ocular Manifestations in Patients of HIV(Human Immunodeficiency Virus) Infection on Combined Anti-Retroviral Therapy (CART).

Apr 05, 2021

: To determine the prevalence and spectrum of ocular manifestations in PLHIV (people living with Human Immunodeficiency Virus) on cART (combined Antiretroviral Therapy) and correlate them with WHO cli...

The Relationship Between Circulating Growth Differentiation Factor 15 Levels and Diabetic Retinopathy in Patients With Type 2 Diabetes.

Apr 05, 2021

Growth differentiation factor 15 (GDF-15) is a member of the TGF- superfamily that has anti-inflammatory properties. The objective of this study was to evaluate the relationship between circulating GD...

Atg16L1 as a Novel Biomarker and Autophagy Gene for Diabetic Retinopathy.

Apr 05, 2021

Accumulating evidence suggests the critical role of autophagy in the pathogenesis of diabetic retinopathy (DR). In the current study, we aim to identify autophagy genes involved in DR via microarray a...

Transcriptome Landscape of Epithelial to Mesenchymal Transition of Human Stem Cell-Derived RPE.

Apr 05, 2021

RPE injury often induces epithelial to mesenchymal transition (EMT). Although RPE-EMT has been implicated in a variety of retinal diseases, including proliferative vitroretinopathy, neovascular and at...

Uveitis-Glaucoma-Hyphema Syndrome: Clinical Features and Differential Diagnosis.

Apr 05, 2021

to study the clinical features of uveitis-glaucoma-hyphema (UGH) syndrome, particularly those useful for a differential diagnosis from unilateral hypertensive acute anterior uveitis. A retrospective ...

Systemic Genotype-Phenotype Analysis of MYOC Variants Based on Exome Sequencing and Literature Review.

Apr 05, 2021

This study aims to characterize disease-causing variants in the myocilin gene (MYOC), which is associated with autosomal dominant primary open-angle glaucoma (adPOAG).Case-control study.MYOC variants ...

Characterizing and quantifying the temporal relationship between structural and functional change in glaucoma.

Apr 05, 2021

To characterize and quantify the temporal relationship between structural and functional change in glaucoma.120 eyes of 120 patients with ocular hypertension or primary open-angle glaucoma were select...

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