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Ophthalmology General

Topically instilled caffeine selectively alters emmetropizing responses in infant rhesus monkeys.

Jan 14, 2021

Oral administration of the adenosine receptor (ADOR) antagonist, 7-methylxanthine (7-MX), reduces both form-deprivation and lens-induced myopia in mammalian animal models. We investigated whether topi...

Visual and Refractive Outcomes With the Eyecryl Phakic Toric IOL Versus the Visian Toric Implantable Collamer Lens: Results of a 2-Year Prospective Comparative Study.

Jan 14, 2021

To compare the 2-year visual and refractive outcomes with the Eyecryl Phakic Toric IOL (EP TIOL) (Biotech Vision Care Pvt Ltd) and Visian Toric ICL (TICL) (STAAR Surgical) for correction of high myopi...

Accuracy of Intraoperative Aberrometry, Barrett True-K With and Without Posterior Cornea Measurements, Shammas-PL, and Haigis-L Formulas After Myopic Refractive Surgery.

Jan 14, 2021

To assess the accuracy of intraoperative aberrometry, the Barrett True-K No History (Barrett TKNH), Barrett TKNH with posterior corneal measurements (Barrett TKNH with PC), Shammas-PL, and Haigis-L fo...

Stabilization of eye drops containing autologous serum and recombinant human epidermal growth factor for dry eye syndrome.

Jan 14, 2021

Human epidermal growth factor (hEGF) and autologous serum are considered safer and more effective in treating dry eye syndrome. However, suitable formulas and preparation methods are needed to obtain ...

The Association between Meibomian Gland Atrophy and Corneal Subbasal Nerve Loss in Patients with Chronic Ocular Graft-versus-host Disease.

Jan 14, 2021

: To investigate the association between meibomian gland (MG) loss and corneal subbasal nerve plexus density in patients with chronic graft-versus-host disease (GVHD) related dry eye disease (DED). : ...

Investigating the Synergistic Interactions of Surface Immobilized and Free Natural Ocular Lubricants for Contact Lens Applications: A Comparative Study between Hyaluronic Acid and Proteoglycan 4 (Lubricin).

Jan 14, 2021

The main reasons for the discontinuation of contact lens wear are ocular dryness and discomfort. Proteoglycan 4 (PRG4), a mucinous glycoprotein, and hyaluronic acid (HA), a nonsulfated linear glycosam...

Impacts of monocular, binocular, and functional visual acuity on vision-related quality of life in patients with type 2 diabetes.

Jan 14, 2021

Although the association between visual acuity (VA) and vision-related quality of life (VRQoL) has been well reported in patients with type 2 diabetes mellitus (T2DM), little is known about how unilat...

Melatonin maintains inner blood-retinal barrier via inhibition of p38/TXNIP/NF-κB pathway in diabetic retinopathy.

Jan 14, 2021

The pathophysiology of diabetic retinopathy (DR) was complex. Under hyperglycemic conditions, the release of proinflammatory cytokines and the adhesion of leukocytes to retinal capillaries contribute ...

Intravitreal bevacizumab versus intravitreal triamcinolone for diabetic macular edema-Systematic review, meta-analysis and meta-regression.

Jan 14, 2021

The most frequent cause of vision loss from diabetic retinopathy is diabetic macular edema (DME). Earlier clinical trials tried to examine the role of intravitreal triamcinolone (IVT) and intravitreal...

Assessment of ocular surface disease in glaucoma patients with benzalkonium chloride-preserved latanoprost eye drops: a short-term longitudinal study.

Jan 14, 2021

To prospectively evaluate the effect of benzalkonium chloride (BAK)-preserved latanoprost on ocular surface damage and identify the associated risk factors among treatment-naive glaucoma patients.The ...

Regulation of distinct caspase-8 functions in retinal ganglion cells and astroglia in experimental glaucoma.

Jan 14, 2021

Retinal ganglion cells (RGCs) expanding from the retina to the brain are primary victims of neurodegeneration in glaucoma, a leading cause of blindness; however, the neighboring astroglia survive the ...

The Distribution of Retinal Venous Pressure and Intraocular Pressure Differs Significantly in Patients with Primary Open-Angle Glaucoma.

Jan 14, 2021

Until now, venous pressure within the eye has widely been equated with intraocular pressure (IOP). Measurements with dynamometers calibrated in instrument units or in force showed that the retinal ven...

Deployment of the Ophthalmic and Facial Angiosomes in the Upper Nose Overlaying the Nasal Bones.

Jan 11, 2021

Nasal filler placement is associated with a high risk of blindness. The arterial supply to the upper nose overlaying the nasal bones is poorly understood.This study attempts to visualize and analyze t...

Behçet disease, New insights in disease associations and manifestations. A next generation sequencing study.

Jan 11, 2021

Behçet disease is a multisystem disease associated with Human Leucocyte Antigen (HLA) class I polymorphism. High-resolution Next Generation Sequencing (NGS) with haplotype analysis has not been perfo...

Vector Analysis of Visual Acuity and Refractive Outcomes of Astigmatic Corrections After T-PRK and Fs-LASIK.

Jan 11, 2021

T Transepithelial photorefractive keratectomy (T-PRK) and femtosecond laser in situ keratomileusis (Fs-LASIK) are reftactive surgery methods for treating myopia and myopic astigmatism. Although T-PRK ...

Comparison of Methods for Estimating Retinal Shape: Peripheral Refraction vs. Optical Coherence Tomography.

Jan 11, 2021

Retinal shape presents a clinical parameter of interest for myopia, and has commonly been inferred indirectly from peripheral refraction (PRX) profiles. Distortion-corrected optical coherence tomograp...

Anterior scleral thickness and shape changes with different levels of simulated convergence.

Jan 11, 2021

Convergence plays a fundamental role in the performance of near visual tasks. We measured the effect of two levels of convergence on anterior scleral thickness and shape in emmetropes, low to moderate...

Impact of comorbid Sjögren syndrome in anti-aquaporin-4 antibody-positive neuromyelitis optica spectrum disorders.

Jan 11, 2021

Neuromyelitis optica spectrum disorders (NMOSD) are autoimmune neurological diseases of the central nervous system, which are characterized by the presence of serum anti-aquaporin-4 autoantibodies (AQ...

Randomised assessormasked trial evaluating topical manuka honey (Optimel) in treatment of meibomian gland dysfunction.

Jan 11, 2021

To evaluate the effects of manuka honey eye-drops in the treatment of meibomian gland dysfunction.This is an assessor-masked (single-blind), randomised controlled trial comparing conventional treatmen...

The relationship between dry eye and sleep quality.

Jan 11, 2021

Sleep is an important determinant of health and quality of life. This study aimed to clarify the association between dry eye and sleep quality using a large population-based cohort.71,761 participants...

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