Jan 28, 2021

Objective Estimate the prevalence of depression among individuals with a dry eye disease (DED) in Saudi Arabia using two questionnaires: Patient Health Questionnaire (PHQ-9) and Dry Eye Questionnaire ...

Jan 28, 2021

To evaluate the role of CD4+ T helper cells in benzalkonium chloride (BAC)-induced ocular surface disorder in C57BL/6 mice.Topical 0.075% BAC was applied twice daily in C57BL/6 mice for 7 consecutive ...

Jan 18, 2021

Small incision lenticule extraction or SMILE is a simple laser eye surgery. It is a minimally invasive procedure for treating refractive errors like astigmatism, hyperopia, presbyopia, and myopia. It ...

Jan 18, 2021

Patients with punctate inner choroidopathy (PIC) require proper eye care. They develop secondary complications like choroidal neovascularization (CNV). Clinicians have to monitor these disorders and p...

Jan 18, 2021

Aging patients have macular degeneration that leads to poor vision. The sharpness of their eyesight depends on the central macular region. A 1 mm diameter zone is crucial for ascertaining the patient'...

Jan 18, 2021

Bacterial keratitis is the infection of the cornea that leads to pain, redness, and blurred vision. Those who wear contact lenses are susceptible to this disease. Low maintenance and cleaning of the l...

Jan 18, 2021

Glaucoma damages the optic nerve and leads to total blindness. Multiple genetic factors affect the adult-onset of this disease. Early-onset is characterized by autosomal dominant or recessive inherita...

Jan 18, 2021

The current methods used to assess visual function in blind retinitis pigmentosa (RP) patients are mostly subjective. We aimed to identify effective, objective methods.We enrolled patients diagnosed w...

Jan 18, 2021

The predictive value of acidemia at birth on long-term neurodevelopmental outcomes remains poorly understood, especially in preterm neonates.This study aimed to assess the relationship between the umb...

Jan 18, 2021

The aim of this study was to compare the visual and refractive outcomes of total keratometry (TK) versus anterior keratometry (AK) measurements of the IOLMaster 700® (Carl Zeiss Meditec AG, Jena, Ger...

Jan 18, 2021

To compare the efficacy and safety of HU00701 (0.01% cyclosporin  + 3% trehalose), HU007 (0.02% cyclosporin  + 3% trehalose) (all w/v), and placebo in patients with moderate to severe dry eye...

Jan 18, 2021

To determine whether reproxalap, a novel reactive aldehyde species (RASP) inhibitor, is safe and effective for the treatment of the signs and symptoms of dry eye disease (DED). In a randomized doubl...

Jan 18, 2021

Pigment Epithelium-derived Factor (PEDF) is a widely expressed 50kD glycoprotein belonging to the serine protease inhibitor family with well-established anti-inflammatory functions. Recently, we demon...

Jan 18, 2021

To evaluate the efficacy of a single intravitreal injection of rAAV2/2-ND4 in subjects with visual loss from Leber hereditary optic neuropathy (LHON).RESCUE is a multicenter, randomized, double-masked...

Jan 18, 2021

Retinal nonperfusion (NP) is a biomarker for assessment of the severity of diabetic retinopathy and retinal vein occlusion. However, various conditions mimic the retinal NP flow void signals that are ...

Jan 18, 2021

Diabetic retinopathy (DR) is the leading cause of blindness among working-aged adults aged 20 to 74 years. Despite professional association guidelines that recommend yearly screening for DR, only ab...

Jan 18, 2021

Optical coherence tomography angiography (OCTA) allows the study of vessel density (VD). We intended to perform a systematic review of studies focusing on longitudinal changes in peripapillary and mac...

Jan 18, 2021

Predicting the therapeutic response to ocular hypotensive drugs is crucial for the clinical treatment and management of glaucoma. Our aim was to identify a possible genetic contribution to the respons...

Jan 18, 2021

This study aimed to establish a deep learning system for detecting the active and inactive phases of thyroid-associated ophthalmopathy (TAO) using magnetic resonance imaging (MRI). This system could p...

Jan 18, 2021

Effective management of diabetic retinopathy requires multidisciplinary input. We aimed to evaluate the impact of point of care (POC) HbA1c testing as a tool to identify patients most in need of speci...