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Ophthalmology General

Efficacy of bevacizumab for vitreous haemorrhage in proliferative diabetic retinopathy with prior complete panretinal photocoagulation.

Jan 11, 2021

To investigate the efficacy of intravitreal bevacizumab injections (IVBs) for vitreous haemorrhage (VH) in proliferative diabetic retinopathy (PDR) with prior complete panretinal photocoagulation (PRP...

Contextualising Single-Arm Trials With Real-World Data: An Emulated Target Trial Comparing Therapies For Neovascular Age-Related Macular Degeneration.

Jan 11, 2021

One-in-four ophthalmology trials are single-armed, which poses challenges to their interpretation. We demonstrate how real-world cohorts used as external/synthetic control arms can contextualise such ...

Development of a zebrafish screening model for diabetic retinopathy induced by hyperglycemia: Reproducibility verification in animal model.

Jan 11, 2021

This study aimed at creating a zebrafish screening model for diabetic retinopathy, and evaluated the effects of aflibercept, which is being used to treated diabetic retinopathy. A morphological change...

Causes of corneal transplant failure: a multicentric study.

Jan 11, 2021

To identify the causes of failure of the different surgical corneal graft techniques: penetrating keratoplasty (PK), deep anterior lamellar keratoplasty (DALK), Descemet stripping automated endothelia...

Cost-effectiveness of dexamethasone and triamcinolone for the treatment of diabetic macular oedema in Finland: A Markov-model.

Jan 11, 2021

Diabetic macular oedema (DMO), a complication of diabetes, causes vision loss and blindness. Corticosteroids are usually used as a second-line treatment. The aim of this study was to analyse the cost-...

Prevalence of MYOC risk variants for glaucoma in different populations.

Jan 11, 2021

To assess the clinical relevance of myocilin (MYOC) gene variants as risk factors for glaucoma in literature and to estimate their prevalence in different populations.We reviewed the literature for pu...

Unilateral lateral rectus recession is an effective surgery for intermittent exotropia in young children.

Jan 11, 2021

Different surgical methods have been suggested for the correction of intermittent exotropia. Unilateral lateral rectus recession has been described as a surgical alternative for small and moderate-ang...

Evaluation of a Home-Printable Vision Screening Test for Telemedicine.

Jan 11, 2021

Many ophthalmology appointments have been converted to telemedicine assessments. The use of a printed vision chart for ophthalmology telemedicine appointments that can be used by people who are exclud...

Identification of amblyogenic risk factors with the Brückner reflex test using the low-cost Arclight direct ophthalmoscope.

Jan 11, 2021

The Arclight is a novel, low-cost, solar-powered direct ophthalmoscope developed for low resource settings as an alternative to more expensive, conventional devices. The Brückner reflex test (BRT) is...

Gender Disparity in Surgical Repair for Retinal Detachment

Jan 07, 2021

Research indicates that women are 34% less likely than men to receive surgical intervention for repair of a rhegmatogenous retinal detachments (RRDs) in the United States. We speculate there are both ...

Estimating principal plane positions for ocular power calculations in children and adults.

Jan 07, 2021

To develop an age-dependent model to estimate the positions of the ocular and lenticular principal planes (pps) for use in ocular and axial power calculations.Ocular power of the eye (P ) and axial po...

Anterior Segment Ischemia After Peripheral Annular Lamellar Sclerokeratoplasty for Advanced Terrien Marginal Degeneration.

Jan 07, 2021

A man with 360° bilateral peripheral thinning, peripheral vascularization, and lipid deposition diagnosed with Terrien marginal degeneration, underwent a 360° peripheral annular lamellar sclerokerat...

[Nystagmus secondary to albinism with ocular involvement in a female: A diagnostic challenge].

Jan 07, 2021

Infantile nystagmus is an infrequent condition that represents a diagnostic challenge for the pediatri cian. Albinism is one of its main causes, being difficult to suspect in the absence of evident cu...

The distribution of conjunctival goblet cells in mice.

Jan 07, 2021

To evaluate the density and distribution of conjunctival goblet cells in mice without clinical evidence of ocular surface diseases.Immediately after euthanasia of C57BL/6 wild-type mice, the eyes incl...

Manuscript title: Developing evidence-based guidance for the treatment of dry eye disease with artificial tear supplements: A six-month multicentre, double-masked randomised controlled trial.

Jan 07, 2021

To assess the six-month therapeutic profiles of lipid and non-lipid-based artificial tear supplements in managing dry eye disease (DED).Ninety-nine participants fulfilling the TFOS DEWS II diagnostic ...

Automatic Detection of Genetics and Genomics of Eye Disease Using Deep Assimilation Learning Algorithm.

Jan 07, 2021

Diabetic retinopathy (DR) is one of the most prevalent genetic diseases in human and it is caused by damage to the blood vessels in the eye retina. If it is undetected and untreated at right time, it ...

The colorful world of carotenoids: a profound insight on therapeutics and recent trends in nano delivery systems.

Jan 07, 2021

The therapeutic effects of carotenoids as dietary supplements to control or even treat some specific diseases including diabetic retinopathy, cardiovascular diseases, bacterial infections, as well as ...

Retinopathy in adults with hypertension and diabetes mellitus in Western Tanzania: a cross-sectional study.

Jan 07, 2021

Little is known about the retinal manifestations of arterial hypertension (HTN) and diabetes mellitus (DM) in Western Tanzania and how to maximise the utilisation of scarce eye health resources. To ad...

Olfactory language and semantic processing in anosmia: a neuropsychological case control study.

Jan 07, 2021

A longstanding debate within philosophy and neuroscience involves the extent to which sensory information is a necessary condition for conceptual knowledge. Much of our understanding of this relations...

NRL gene edited human embryonic stem cells generate rod-deficient retinal organoids enriched in S-cone-like photoreceptors.

Jan 07, 2021

Organoid cultures represent a unique tool to investigate the developmental complexity of tissues like the human retina. NRL is a transcription factor required for the specification and homeostasis of ...

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