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Orthopedics General

Clinical Spectrum

Oct 01, 2021

This study states that The ABCA4 protein (then called a “rim protein”) was first identified in 1978 in the rims and incisures of rod photoreceptors. The corresponding gene, ABCA4, was cloned in 19...

Endoplasmic Reticulum Stress

Oct 01, 2021

This study states that Physiological equilibrium in the retina depends on coordinated work between rod and cone photoreceptors and can be compromised by the expression of mutant proteins leading to in...

Secretory Proteostasis Of The Retinal Pigmented Epithelium

Sep 28, 2021

Secretory proteostasis integrates protein synthesis, processing, folding and trafficking pathways that are essential for efficient cellular secretion. For the retinal pigment epithelium (RPE), secreto...

Extracellular Vesicle Therapy

Sep 28, 2021

Extracellular vesicles (EV), which include exosomes and microvesicles, are secreted from virtually every cell. EV contain mRNA, miRNA, lipids and proteins and can deliver this expansive cargo into nea...

Mechanisms Of Mitochondrial Dysfunction

Sep 28, 2021

The aim of this study is to Oxidative stress-induced damage to the retinal pigment epithelium (RPE) is considered to be a key factor in age-related macular degeneration (AMD) pathology. RPE cells are ...

Activation Of The Interleukin-23/Interleukin-17

Sep 28, 2021

This study states that Uveitis is a group of diseases characterized by intraocular inflammation, of which some are driven by autoinflammatory or autoimmune responses, such as Vogt-Koyanagi-Harada dise...

Molecular Components Affecting Ocular

Sep 28, 2021

This study states that The photochemistry of vision employs opsins and geometric isomerization of their covalently bound retinylidine chromophores. In different animal classes, these light receptors a...

Plexus-Specific Retinal Vascular Anatomy

Sep 28, 2021

This study states that Optical coherence tomographic angiography (OCTA) is a novel technology capable of imaging retinal vasculature three-dimensionally at capillary scale without the need to inject a...

Splicing Mutations

Sep 28, 2021

This study states that Mutations which induce aberrant transcript splicing represent a distinct class of disease-causing genetic variants in retinal disease genes. Such mutations may either weaken or ...

Critical Analysis Of Techniques

Sep 28, 2021

This system review states that Intravitreal injections have become the most commonly performed intraocular treatments worldwide. Because intravitreal injections may induce severe adverse events, such ...

Plasmacytoid Dendritic Cells In The Eye

Sep 28, 2021

This observation has been performed so as to understand Plasmacytoid dendritic cells (pDCs) are a unique subpopulation of immune cells, distinct from classical dendritic cells. pDCs are generated in t...

Corneal Xenotransplantation

Sep 28, 2021

This study defines The search for alternatives to allotransplants is driven by the shortage of corneal donors and is demanding because of the limitations of the alternatives. Indeed, current progress ...

Root Fracture and Extrusive Luxation in Primary Teeth and Their Management: A Case Report.

Sep 27, 2021

Extrusion, lateral luxation, and intrusion are among the most serious types of dental trauma. Only a few studies have specifically focused on extrusion; the present one was aimed at reporting a case o...

Outpatient and Home-Based Treatment: Effective Settings for Hip Fracture Rehabilitation in Elderly Patients.

Sep 27, 2021

Femoral neck fractures are a major source of disability in the elderly. Rehabilitation is fundamental to recover pre-fracture functionality. We conducted an observational cohort study with the aim of ...

Fuchs Endothelial Corneal Dystrophy

Sep 22, 2021

This study has been performed so as to understand Fuchs endothelial corneal dystrophy (FECD) is the most common primary corneal endothelial dystrophy and the leading indication for corneal transplanta...

TCF4-Mediated Fuchs Endothelial Corneal Dystrophy

Sep 22, 2021

Fuchs endothelial corneal dystrophy (FECD) is a common cause for heritable visual loss in the elderly. Since the first description of an association between FECD and common polymorphisms situated with...

Personalising Surgical Treatments

Sep 22, 2021

Surgical treatments for glaucoma have relied for decades on traditional filtering surgery such as trabeculectomy and, in more challenging cases, tubes. Antifibrotics were introduced to improve surgica...

Retina In A Dish

Sep 22, 2021

This study states that For many retinal diseases, including age-related macular degeneration (AMD), glaucoma, and diabetic retinopathy (DR), the exact pathogenesis is still unclear. Moreover, the curr...

Pathogenesis Of Ocular Toxoplasmosis

Sep 22, 2021

Ocular toxoplasmosis is a retinitis –almost always accompanied by vitritis and choroiditis– caused by intraocular infection with Toxoplasma gondii. Depending on retinal location, this condition ma...

Non-Specific Orbital Inflammation

Sep 21, 2021

The aim of this study is to understand how Vague orbital aggravation is a noninfectious incendiary state of the circle. In spite of the fact that it is by and large viewed as the most well-known deter...

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