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Orthopedics General

Immune Responses To Retinal Gene Therapy

Sep 16, 2021

Recombinant adeno-associated virus (AAV) is the leading vector for gene therapy in the retina. As non-pathogenic, non-integrating, replication deficient vector, the recombinant virus efficiently trans...

Past, Present And Future Role Of Retinal Imaging

Sep 15, 2021

This study states Retinal imaging technology is rapidly advancing and can provide ever-increasing amounts of information about the structure, function and molecular composition of retinal tissue in hu...

The Vital Role For Nitric Oxide

Sep 15, 2021

This study states that Catalyzed by endothelial nitric oxide (NO) synthase (eNOS) activity, NO is a gaseous signaling molecule maintaining endothelial and cardiovascular homeostasis. Principally, NO r...

Clinical Vision And Molecular loss

Sep 15, 2021

This study states that Over the past two decades we have developed techniques and models to investigate the ways in which known molecular defects affect visual performance. Because molecular defects i...

Inflammation In Glaucoma

Sep 15, 2021

The study states that The pathophysiology of glaucoma is complex, multifactorial and not completely understood. Elevated intraocular pressure (IOP) and/or impaired retinal blood flow may cause initial...

Aqueous Outflow Regulation

Sep 14, 2021

The main  propose is an integrated model of aqueous outflow control that employs a pump-conduit system in this article. Our model exploits accepted physiologic regulatory mechanisms such as those of ...

Efficacy In Myopia Control

Sep 14, 2021

There is rapidly expanding interest in interventions to slow myopia progression in children and teenagers, with the intent of reducing risk of myopia-associated complications later in life. Despite ma...

Optic Nerve Head Anatomy

Sep 14, 2021

The aim of this study is to understand The optic nerve head can morphologically be differentiated into the optic disc with the lamina cribrosa as its basis, and the parapapillary region with zones alp...

Uncoupling Proteins In The Mitochondrial

Sep 14, 2021

This study states that Oxidative stress is a major component of most major retinal diseases. Many extrinsic anti-oxidative strategies have been insufficient at counteracting one of the predominant int...

Dominant Optic Atrophy

Sep 14, 2021

This study states that Dominant optic atrophy (DOA) is an inherited mitochondrial disease leading to specific degeneration of retinal ganglion cells (RGCs), thus compromising transmission of visual in...

Diabetes Impairs Fracture Healing Through Disruption Of Cilia Formation In Osteoblasts.

Sep 13, 2021

Diabetes-associated fracture risk and impaired fracture healing represents a serious health threat. It is well known that type 1 diabetes mellitus (T1DM) impairs fracture healing due to its effect on ...

Clinical outcomes of thoracolumbar burst fracture treated by trans-Kambin's triangle versus transpedicular bone grafting combined with posterior internal fixation.

Sep 13, 2021

The ideal management of thoracolumbar burst fracture (TLBF) remains controversial. We conducted this study to compare the effectiveness and safety of trans-Kambin's triangle versus transpedicular bone...

Unusual combination of posterior cruciate ligament tibial avulsion fracture and Segond fracture: A case report.

Sep 13, 2021

Posterior cruciate ligament (PCL) avulsion fracture is an uncommon entity, but it poses significant morbidity to patient's knee and activities. A combination of PCL avulsion fracture with Segond fract...

Three-dimensional porous reduced graphene oxide/hydroxyapatite membrane for guided bone regeneration.

Sep 13, 2021

The guided bone regeneration (GBR) membrane is intended to provide sufficient space for alveolar bone regeneration and meanwhile prevent the invasion of gingival epithelium. In this study, three-dimen...

Polyvinyl alcohol hydrolysis rate and molecular weight influence human and murine HSC activity ex vivo.

Sep 13, 2021

Ex vivo expansion of hematopoietic stem cells (HSCs) is one of the most promising strategies to increase the availability of transplantable HSCs and improve bone marrow transplantation outcomes. We re...

Disrupted somatosensory input alters postural control strategies during the Star Excursion Balance Test (SEBT) in healthy people.

Sep 06, 2021

Chronic adaptations, including persistent sensorimotor deficits, remain in individuals with a history of ankle instability, resulting in altered postural control strategies during functional tasks suc...

Urinary symptoms in older people with low back pain: Prevalence, clinical, and functional factors associated.

Sep 06, 2021

To identify the prevalence, clinical and functional factors associated with urinary symptoms (US) in community-dwelling older adults with acute low back pain (LBP).This was a cross-sectional study of ...

Analytical model for the prediction of permeability of triply periodic minimal surfaces.

Sep 06, 2021

Triply periodic minimal surfaces (TPMS) are mathematically defined cellular structures whose geometry can be quickly adapted to target desired mechanical response (structural and fluid). This has made...

Toward optoacoustic sciatic nerve detection using an all-fiber interferometric-based sensor for endoscopic smart laser surgery.

Sep 06, 2021

Laser surgery requires efficient tissue classification to reduce the probability of undesirable or unwanted tissue damage. This study aimed to investigate acoustic shock waves (ASWs) as a means of cla...

Clinical Outcomes of Reverse Total Shoulder Arthroplasty for Elective Indications versus Acute Three and Four-Part Proximal Humerus Fractures: A Systematic Review and Meta-Analysis.

Aug 30, 2021

The reverse total shoulder arthroplasty (RTSA) has continued to increase in clinical utility and popularity as an effective treatment for cuff tear arthropathy (CTA), irreparable rotator cuff tear (RC...

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