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Orthopedics General

Current and Emerging Techniques in Articular Cartilage Repair.

Mar 04, 2024

Osteochondral lesions (OCL) of the knee are a common pathology that can be challenging to address. Due to the innate characteristics of articular cartilage, OCLs generally do not heal in adults and of...

Bone biochemistry in children with fractures presenting with non-accidental injury.

Mar 04, 2024

In cases of fractures in children with suspicion of non-accidental injury (NAI), biochemical markers of calcium homeostasis should be performed.To describe the pattern of biochemistry in children with...

Let's settle the controversy-gelfoam is a safe intravascular embolic agent.

Feb 26, 2024

A 2021 safety alert restricted endovascular gelfoam use in Australia and resulted in an embargo on gelfoam sales to IR departments. This study aimed to show that gelfoam is safe in a population of tra...

Pathological fracture treated with total femoral replacement in a case of chondrosarcoma involving the entire-length femoral shaft.

Feb 26, 2024

We here present a case of chondrosarcoma of the diaphysis of the femur with extensive involvement of the length of the bone and with the pathological fracture at the mid-shaft level. Total femur repla...

Effects of testing speed on the tensile and mode I fracture behavior of specimens printed through the Fused Deposition Modeling technique.

Feb 19, 2024

Additive Manufacturing (AM) processes are known as revolutionary manufacturing processes that fabricate a part using a 3D model layer upon layer. These techniques gained more attention from various in...

A Case of Thoracic Empyema Caused by Actinomyces naeslundii.

Feb 19, 2024

BACKGROUND Actinomycosis is a clinically significant but uncommon infectious disease caused by anaerobic commensals of Actinomyces species, and the incidence of thoracic empyema is rare. We report an ...

Novel sheep model to assess critical-sized bone regeneration with periosteum for in-vivo bioreactors.

Feb 19, 2024

Considerable research is being undertaken to develop novel biomaterials-based approaches for surgical reconstruction of bone defects. This extends to 3D printed materials that provide stable, structur...

Effective growth hormone replacement with once-weekly somapacitan in Japanese children with growth hormone deficiency: Results from REAL4, a phase 3 clinical trial.

Feb 19, 2024

Somapacitan is a long-acting growth hormone(GH) derivative developed for the treatment of GH deficiency (GHD). This study evaluates the efficacy and tolerability of somapacitan in Japanese children w...

Comparison of cutout risk factors between single- and doublescrew proximal nails in intertrochanteric femur fractures - a multicentric study.

Feb 12, 2024

Aim Significant risk factors for femoral nail cutout are well-documented, primarily in the context of single-screw proximal nails. However, it remains uncertain whether those same risk factors are app...

SERTAD1 initiates NLRP3-mediated inflammasome activation through restricting NLRP3 polyubiquitination.

Feb 12, 2024

We here demonstrate that SERTAD1 is an adaptor protein responsible for the regulation of lysine 63 (K63)-linked NLRP3 polyubiquitination by the Cullin1 E3 ubiquitin ligase upon inflammasome activation...

Thoracic spine X-ray examination of patients with back pain using different breathing technique and exposure times - A diagnostic study.

Feb 05, 2024

The breathing and suspended inspiration techniques are often used interchangeably for spine X-ray examinations. However, these techniques are not always adequately supported by clinical evidence. This...

A CRISPR base editing approach for the functional assessment of telomere biology disorder-related genes in human health and aging.

Feb 05, 2024

Telomere Biology Disorders (TBDs) are a group of rare diseases characterized by the presence of short and/or dysfunctional telomeres. They comprise a group of bone marrow failure syndromes, idiopathic...

Comparison of clinical outcomes and complications between endoscopic and minimally invasive transforaminal lumbar interbody fusion for lumbar degenerative diseases: a systematic review and meta-analysis.

Jan 29, 2024

This study compares the efficacy and complications of endoscopic transforaminal lumbar fusion (Endo-TLIF) and minimally invasive transforaminal lumbar fusion (MIS-TLIF) in treating lumbar degenerative...

A case of hepatocellular carcinoma with pseudoaneurysm formation upon lenvatinib administration.

Jan 29, 2024

A 79-year-old man received treatment for multiple intrahepatic hepatocellular carcinoma with atezolizumab + bevacizumab. However, he developed lower back pain attributed to spinal metastases upon ...

Material-Intrinsic NIR-Fluorescence Enables Image-Guided Surgery for Ceramic Fracture Removal.

Jan 22, 2024

Hip arthroplasty effectively treats advanced osteoarthritis and has therefore been entitled as "operation of the 20th century." With demographic shifts, the USA alone is projected to perform up to 850...

Self-Healing Micro Arc Oxidation and Dicalcium Phosphate Dihydrate Double-Passivated Coating on Magnesium Membrane for Enhanced Bone Integration Repair.

Jan 22, 2024

Magnesium is a revolutionary biomaterial for orthopedic implants, owing to its eminent mechanical properties and biocompatibility. However, its uncontrolled degradation rate remains a severe challenge...

A comparison of continuous cold flow and compression device and traditional icing regimen and no icing following anterior cruciate ligament reconstruction: A pilot study.

Jan 15, 2024

The aim of this study was to investigate the effectiveness of continuous cold flow and compression device as against traditional icing regimen and without icing after anterior cruciate ligament (ACL) ...

Complications related to unwitnessed magnet ingestion in paediatrics: Case series.

Jan 15, 2024

Foreign body inges tion is one of the mo s t common problems a mo ng chi ldren. There is a great te ndency among children between the age of six months to six years to p lace objects, such as coins, f...

Association of ACE*(Insertion/Deletion) Variant with the Elevated Risk of Preeclampsia Among Gestational Women.

Jan 15, 2024

The renin-angiotensin-aldosterone system has an indispensable function in the uteroplacental circulation, placental growth, and blood pressure optimization. The angiotensin I converting enzyme (ACE) g...

Characterization of movement patterns using unsupervised learning neural networks: Exploring a novel approach for monitoring athletes during sidestepping.

Jan 08, 2024

The monitoring of athletes is crucial to preventing injuries, identifying fatigue or supporting return-to-play decisions. The purpose of this study was to explore the ability of Kohonen neural network...

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