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Orthopedics General

Optimized protocols for in situ hybridization, immunohistochemistry, and immunofluorescence on skeletal tissue.

Jul 05, 2021

Assessment of gene and protein expression in tissue sections is instrumental in medical research. However, this is often challenging to perform on skeletal tissues that require prolonged decalcificati...

The concerns of oncology professionals during the COVID-19 pandemic: results from the ESMO Resilience Task Force survey II.

Jul 05, 2021

The COVID-19 pandemic has resulted in significant changes to professional and personal lives of oncology professionals globally. The European Society for Medical Oncology (ESMO) Resilience Task Force ...

A New Arthroscopic Tightrope Suture-Button Fixation Procedure for Tibial Eminence Avulsion Fracture.

Jul 01, 2021

This case-series outcome study presents a new arthroscopic technique for tibial eminence avulsion fracture (TEAF) with double-tunnel using two tightrope suture buttons. From May 2017 to July 2020, we ...

A preliminary systematic review and meta-analysis on the effects of heart rate variability biofeedback on heart rate variability and respiration of athletes.

Jul 01, 2021

To date, there is no quantitative review examining the influence of heart rate variability biofeedback (HRV BFB) on the athlete population. Such an undertaking may provide valuable information on the ...

The FIFA 11+ does not alter performance in amateur female basketball players-a randomized control trial.

Jul 01, 2021

The FIFA-Medical and Assessment Research Centre (F-MARC) introduced the warm-up FIFA 11+ program to reduce injuries and promote fair play. Although the FIFA11+ program is a well-established warm-up pr...

Multivariate analysis of geographic variation in Darevskia clarkorum (Darevsky amp; Vedmederja, 1977), correlation with geographic and climatic parameters, and true status of Darevskia dryada (Darevsky amp; Tuniyev, 1997).

Jul 01, 2021

All the Turkish populations studied, both those previously assigned to D. dryada (Subaşı and Yoldere villages, near Hopa) and those attributed to D. clarkorum (the largest sample studied so far, 177...

Distal Femoral Replacement for Fractures Allows for Early Mobilization with Low Complication Rates: A Multicenter Review.

Jul 01, 2021

Periprosthetic fractures around a total knee arthroplasty (TKA), comminuted and intra-articular femur fractures, or fracture nonunions in osteoporotic bone represent technically challenging problems. ...

Osteoporosis, fracture, osteoarthritis & sarcopenia: A systematic review of circulating microRNA association.

Jun 28, 2021

Circulating microRNAs (c-miRs) show promise as biomarkers. This systematic review explores their potential association with age-related fracture/osteoporosis (OP), osteoarthritis (OA) and sarcopenia (...

Frontal plane ankle stiffness increases with weight-bearing.

Jun 28, 2021

Ankle sprains are among the most common musculoskeletal injuries. They are not isolated innocuous injuries as 30-40% of people who sprain their ankles develop chronic ankle instability. Ankle instabil...

Effects of Dexmedetomidine as an Analgesic Adjuvant for Surgery of Femur Fracture: A Systematic Review and Meta-Analysis.

Jun 28, 2021

Patients who undergo surgery of femur fracture suffer the excruciating pain. Dexmedetomidine (DEX) is a unique α2-adrenergic receptor agonist with sedative and analgesic properties, whose efficacy an...

Underground Down Under: Skull anatomy of the southern blind snake Anilios australis Gray, 1845 (Typhlopidae: Serpentes: Squamata).

Jun 28, 2021

The cranial anatomy of blindsnakes has been markedly understudied, with the small size and relative rarity of encountering these subterranean reptiles being significant limiting factors. In this artic...

Orofacial trauma injuries and disability assessment in adolescents: A Portuguese study.

Jun 24, 2021

Orofacial injuries are a significant public health issue. The evidence-based knowledge associated with adolescent violence and trauma is highlighted by the World Health Organization with regard to its...

Polygenic Risk Scores have high diagnostic capacity in ankylosing spondylitis.

Jun 24, 2021

We sought to test the hypothesis that Polygenic Risk Scores (PRSs) have strong capacity to discriminate cases of ankylosing spondylitis (AS) from healthy controls and individuals in the community with...

Influence of unstable shoes on women with lumbopelvic postpartum pain: randomized clinical trial.

Jun 24, 2021

Back pain is a normal symptom during pregnancy and is expected to become worse beyond the first three months after childbirth.To determine the effectiveness of wearing unstable shoes instead of conven...

Endodontic and Periodontal Treatment of Complete Buccal Root and Apex Exposition: A Challenging Case Report with 17 Months Follow-Up.

Jun 24, 2021

This case report demonstrated a challenging clinical case addressed within a multidisciplinary approach to achieve its maintenance, even though had a poor prognosis. It was associated with the endodon...

Growth hormone treatment and bone mineral density in pediatric patients with Prader-Willi syndrome.

Jun 24, 2021

Previous reports indicate that growth hormone (GH) treatment for Prader-Willi syndrome (PWS) improves bone mineral density (BMD) only when initiated at a young age and not when initiated in adulthood....

AGEs promote calcification of HASMCs by mediating Pi3k/AKT-GSK3β signaling.

Jun 24, 2021

This study aimed to investigate the effects of advanced glycation end products (AGEs) on the calcification of human arterial smooth muscle cells (HASMCs) and to explore whether AGEs can promote the ca...

No Detectable Alteration of Inorganic Allogeneic Bone Matrix Colonizing Mesenchymal Cells: A Step Towards Personalized Bone Grafts.

Jun 17, 2021

During major bone substance loss, secured allogeneic bone matrix (ABM) is normally utilized for bone repair. Here, we propose a method to colonize ABM using autologous mesenchymal cells (MCs) to impro...

Stress Fracture of the Femoral Shaft in Paget's Disease of Bone: A Case Report.

Jun 17, 2021

Paget's disease of bone (PDB) is a progressive bone disorder characterized by increased osteoclast-mediated bone resorption and abnormal bone formation. Incomplete atypical femoral fracture, appearing...

A rare case of large left internal maxillary artery pseudoaneurysm secondary to mandibular fracture: A case report and review of the literature.

Jun 14, 2021

Pseudoaneurysms secondary to traumatic vessel wall disruption are a rare but potentially fatal complication after traumatic injury. The majority of the cases are found incidentally.An 80-year-old woma...

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