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Orthopedics General

Sporadic High Pacing and Shock Impedance at Remote Monitoring in Hybrid Implantable Cardioverter Defibrillators Systems: Clinical Impact and Management.

Apr 12, 2021

Sporadic high impedance values without other anomalies have been recently described by remote monitoring for hybrid cardiac implantable electronic device (CIED) systems. The clinical significance and ...

Early Outcomes of Surgical Stabilisation of Traumatic Rib Fractures: Single-Center Review With a Real-World Evidence Perspective.

Apr 12, 2021

Randomized controlled trials have demonstrated that surgical stabilization of rib fractures (SSRF) in selected trauma patients is associated with potential benefits. This study evaluates the real-worl...

Optimized BMSC-derived osteoinductive exosomes immobilized in hierarchical scaffold via lyophilization for bone repair through Bmpr2/Acvr2b competitive receptor-activated Smad pathway.

Apr 12, 2021

Mesenchymal stem cell-derived exosomes (MSC-exos), with its inherent capacity to modulate cellular behavior, are emerging as a novel cell-free therapy for bone regeneration. Herein, focusing on practi...

Interface analysis after fatigue loading of adhesively luted bundled fiber posts to human root canal dentin.

Apr 08, 2021

The aim of this study was to assess the fatigue loading behavior and fracture resistance of endodontically treated teeth restored with adhesively luted bundled fiber posts in comparison to solid fiber...

Mind the gap - Evaluation of the promotion initiatives for implementation of the GLA:D® back clinician courses.

Apr 08, 2021

Translation of research into practice is a methodological challenge. The GLA:D® Back program was initiated to implement evidence-based care for people with low back pain inspired by GLA:D® (Good Lif...

Triple Growth Factor Delivery Promotes Functional Bone Regeneration Following Composite Musculoskeletal Trauma.

Apr 08, 2021

Successful bone healing in severe trauma depends on early revascularization to restore oxygen, nutrient, growth factor, and progenitor cell supply to the injury. Therapeutic angiogenesis strategies ha...

Understanding the impact of lumbar disc degeneration and chronic low back pain: A cross-sectional electromyographic analysis of postural strategy during predicted and unpredicted postural perturbations.

Apr 05, 2021

People with chronic low back pain (LBP) exhibit changes in postural control. Stereotypical muscle activations resulting from external perturbations include anticipatory (APAs) and compensatory (CPAs) ...

Are neuromuscular adaptations present in people with recurrent spinal pain during a period of remission? a systematic review.

Apr 05, 2021

A plethora of evidence supports the existence of neuromuscular changes in people with chronic spinal pain (neck and low back pain), yet it is unclear whether neuromuscular adaptations persist for peop...

Fracture strength analysis of titanium insert-reinforced zirconia abutments according to the axial height of the titanium insert with an internal connection.

Apr 05, 2021

This study aimed to analyze fracture strength in vitro by varying the axial height of the titanium insert and the labial height of the zirconia abutment in an internal connection implant to identify t...

Clinical predictors for analgesic response to radiotherapy in patients with painful bone metastases.

Apr 05, 2021

Radiotherapy (RT) reduces pain in about 60% of patients with painful bone metastases, leaving many patients without clinical benefit. This study assesses predictors for RT effectiveness in patients wi...

Ruxolitinib rechallenge in resistant or intolerant patients with myelofibrosis: Frequency, therapeutic effects, and impact on outcome.

Apr 05, 2021

After ruxolitinib discontinuation, the outcome of patients with myelofibrosis (MF) is poor with scarce therapeutic possibilities.The authors performed a subanalysis of an observational, retrospective ...

Musculoskeletal Health in Premature Ovarian Insufficiency. Part Two: Bone.

Apr 01, 2021

Accelerated bone loss and muscle loss coexist in women with premature ovarian insufficiency (POI), but there are significant gaps in our understanding of musculoskeletal health in POI. This review des...

A Comparative Mechanical Study of Two Types of Femur Bone Implant Using the Finite Element Method.

Mar 29, 2021

The femoral bone fracture is one of the most common fractures that orthopedic surgeons deal with. These fractures are associated with a significant percentage of death due to non-orthopedic complicati...

Biodegradable cement augmentation of gamma nail osteosynthesis reduces migration in pertrochanteric fractures, a biomechanical in vitro study.

Mar 29, 2021

Cut-out of gamma nail often results from poor primary bone stability, suboptimal reduction (varus) and excentric placement of the head element which may lead to "instability" and frequently requires r...

Synthesis and evaluation of magnesium/co-precipitated hydroxyapatite based composite for biomedical application.

Mar 29, 2021

Owing to its inductive attributes, hydroxyapatite is an ideal reinforcement to tailor the degradation kinetics of magnesium-based temporary orthopedic implants. However, the large difference in the me...

Effects of printing path and material components on mechanical properties of 3D-printed polyether-ether-ketone/hydroxyapatite composites.

Mar 29, 2021

Polyether-ether-ketone (PEEK) exhibits excellent mechanical properties and biocompatibility. Three-dimensional (3D) printing of PEEK bone substitutes has been widely used in clinical application. Howe...

Time Course of Neuromuscular, Hormonal, and Perceptual Responses Following Moderate- and High-Load Resistance Priming Exercise.

Mar 25, 2021

The aim of this study was to map responses over 32 hours following high-load (HL) and moderate-load (ML) half-squat priming.Fifteen participants completed control, HL (87% 1RM), and ML (65% 1RM) activ...

The Effect of Attending Physical Rehabilitation After the First Acute Lateral Ankle Sprain on Static Postural Control in Patients With Chronic Ankle Instability.

Mar 25, 2021

Static postural control deficits are commonly documented among individuals with chronic ankle instability (CAI). Evidence suggests individuals with CAI who seek medical attention after an ankle sprain...

Hyperbaric oxygen treatment in recurrent development of complex regional pain syndrome: A case report.

Mar 25, 2021

A broad spectrum of conditions including neuropathic pain, complex regional pain syndrome (CRPS) and fibromyalgia, have been implicated as causes of chronic pain. There is a need for new and effective...

Operationalizing Treat-to-Target for Osteoporosis.

Mar 25, 2021

Treat-to-target (TTT) for osteoporosis is a concept for individualizing patient treatment decisions that focuses on achieving an acceptable level of fracture risk rather than response to treatment alo...

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