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Orthopedics General

Cefoxitin treatment of MRSA leads to a shift in the IL-12/IL-23 production pattern in dendritic cells by a mechanism involving changes in the MAPK signaling.

Mar 08, 2021

Methicillin resistant Staphylococcus aureus (MRSA) constitute a serious health care problem worldwide. This study addresses the effect of β-lactam treatment on the ability of clinically relevant MRSA...

Effects of alternatively used thermal treatments on the mechanical and fracture behavior of dental resin composites with varying filler content.

Mar 04, 2021

The purpose of this study was two-fold: (i) to investigate whether the thermal treatment of direct dental resin composites (RCs) using microwave or autoclave heating cycles would modify the materials'...

Criterion Validity of a Field-Based Assessment of Aerobic Capacity in Wheelchair Rugby Athletes.

Mar 04, 2021

To confirm whether peak aerobic capacity determined during laboratory testing could be replicated during an on-court field-based test in wheelchair rugby players.Sixteen wheelchair rugby players perfo...

Preoperative Cerebrospinal Fluid Cortisol and the Risk of Postoperative Delirium: A Prospective Study of Older Hip Fracture Patients.

Mar 04, 2021

Ageing, depression, and neurodegenerative disease are common risk factors for delirium in the elderly. These risk factors are associated with dysregulation of the hypothalamic-pituitary-adrenal axis, ...

Quantitative measures of bone shape, cartilage morphometry and joint alignment are associated with disease in an ACLT and MMx rat model of osteoarthritis.

Mar 04, 2021

Multi-scale, subject-specific quantitative methods to characterize and monitor osteoarthritis in animal models and therapeutic treatments could help reveal causal relationships in disease development ...

The Change of Plane of the Supratrochlear and Supraorbital Arteries in the Forehead - An Ultrasound-Based Investigation.

Mar 04, 2021

Injecting soft tissue fillers into the deep plane of the forehead carries the risk of injection related visual compromise due to the specific course of the arterial vasculature.To investigate the 2- a...

The transCampus Metabolic Training Programme Explores the Link of SARS-CoV-2 Virus to Metabolic Disease.

Mar 04, 2021

Currently, we are experiencing a true pandemic of a communicable disease by the virus SARS-CoV-2 holding the whole world firmly in its grasp. Amazingly and unfortunately, this virus uses a metabolic a...

Do chronic low back pain subgroups derived from dynamic quantitative sensory testing exhibit differing multidimensional profiles?

Mar 01, 2021

The relationship of pain sensitivity with pain and disability in low back pain (LBP) is complicated. It has been suggested increased understanding of dynamic quantitative sensory testing (QST) might b...

Tired of Being Ignored: Fatigue as a Presenting Symptom in Primary Hyperparathyroidism.

Mar 01, 2021

Fatigue is a common presenting symptom in primary hyperparathyroidism (PHPT). Although fatigue alone is not currently an indication for parathyroidectomy, it can have a significant detrimental effect ...

β-Tricalcium phosphate contained beaded-fiber scaffolds characterized by high early osteoinductive activity for vascularized bone regeneration.

Mar 01, 2021

The calcium phosphate component and surface topology of a scaffold are considered the two main factors that influence osteogenic differentiation. This research reports a one-step but effective scaffol...

Protectin D1 decreases pancreatitis severity in mice by inhibiting neutrophil extracellular trap formation.

Mar 01, 2021

Docosahexaenoic acid-derived protectin D1 (PD1) was identified critical in the resolution of inflammation in vivo, where it modulates the innate immune response and stimulates resolution. Acute pancre...

Sol-Gel Synthesis, in vitro Behavior, and Human Bone Marrow-Derived Mesenchymal Stem Cell Differentiation and Proliferation of Bioactive Glass 58S.

Mar 01, 2021

Bioactive glasses 58S, are silicate-based materials containing calcium and phosphatewhich dissolved in body fluid and bond to the bone tissue. This type of bioactive glass is highly biocompatibile and...

Custom-made polyurethane-based synthetic bones mimic screw cut-through of intramedullary nails in human long bones.

Feb 25, 2021

Intramedullary nails are considered the gold standard for the treatment of tibial shaft fractures. Thereby, the screw-bone interface is considered the weakest link. For biomechanical evaluation of ost...

Injury Patterns in Pediatric Facial Fractures Unique to an Urban Environment.

Feb 25, 2021

This study aimed to define better the clinical presentation, fracture patterns, and features predictive of associated injuries and need for surgery in pediatric facial trauma patients in an urban sett...

New Frontiers of Body Composition in Sport.

Feb 25, 2021

The body composition phenotype of an athlete displays the complex interaction among genotype, physiological and metabolic demands of a sport, diet, and physical training. Observational studies dominat...

Bone health in idiopathic inflammatory myopathies.

Feb 22, 2021

To review the extant literature relating to bone health in the idiopathic inflammatory myopathies (IIM) including both adult and juvenile patients.A PubMed search® identified relevant studies from 19...

Psychological Methods of Managing Surgical Pain.

Feb 18, 2021

In patients who experience chronic or acute wound pain, analgesic requirements as well as patient-centered and clinical outcomes can be affected by psychological interventions as explored by considera...

30-day mortality after hip fracture surgery: Influence of postoperative factors.

Feb 18, 2021

The 30-day mortality rate after hip fracture surgery has been considered as an indirect indicator of the quality of care. The aim of this work is to analyse preoperative and postoperative factors pote...

A neuroskeletal atlas: spatial mapping and contextualization of axon subtypes innervating the long bones of C3H and B6 mice.

Feb 18, 2021

Nerves in bone play well-established roles in pain and vasoregulation and have been associated with progression of skeletal disorders including osteoporosis, fracture, arthritis and tumor metastasis. ...

Isolation and establishment of skin-derived and mesenchymal cells from south American bat Artibeus planirostris (Chiroptera - Phyllostomidae).

Feb 18, 2021

Animal models represent a crucial tool for biological research, so the establishment of new cultures is fundamental for the discovery of new therapies and the understanding of mechanisms of cell devel...

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