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Orthopedics General

Model-based dual-energy tomographic image reconstruction of objects containing known metal components.

Oct 29, 2020

Dual-energy (DE) decomposition has been adopted in orthopedic imaging to measure bone composition and visualize intraarticular contrast enhancement. One of the potential applications involves monitori...

Trabecular Bone is Increased in a Rat Model of Polycystic Ovary Syndrome.

Oct 29, 2020

Polycystic ovary syndrome (PCOS) in an intricate disorder characterized by reproductive and metabolic abnormalities that may affect bone quality and strength along with the lifespan. The present study...

Screw-in-screw fixation of fragility sacrum fracturesprovides high stability without loosening - Biomechanicalevaluation of a new concept.

Oct 26, 2020

Surgical treatment of fragility sacrum fractureswith percutaneous sacroiliac (SI) screw fixation is associated with high failure rates. Turn-out is detected in up to 20% of the patients. The aim of th...

Prevalence of sports-related spinal injury stratified by competition level and return to play guidelines.

Oct 26, 2020

Spinal injury is among the most severe and feared injuries an athlete may face. We present an up-to-date review of the recent literature, stratifying recommendations based on injury location (cervical...

Effectiveness of Photobiomodulation as an Adjunct to Non-surgical Periodontal Therapy in the Management of Periodontitis- A Systematic Review of in vivo Human Studies.

Oct 26, 2020

Photobiomodulation therapy (PBMT) has anti-inflammatory, analgesic and regenerative properties. This systematic review aimed to critically appraise the published data of in vivo human randomized clini...

Clinical utilization of blinatumomab and inotuzumab immunotherapy in children with relapsed or refractory B-acute lymphoblastic leukemia.

Oct 26, 2020

The treatment paradigm for patients with relapsed/refractory B-cell acute lymphoblastic leukemia (rrALL) has been revolutionized given recent clinical trials demonstrating remarkable success of immuno...

European Consensus Statement on the diagnosis and management of osteoporosis in chronic kidney disease stages G4-G5D.

Oct 26, 2020

Controlling the excessive fracture burden in patients with chronic kidney disease (CKD) Stages G4-G5D remains an impressive challenge. The reasons are 2-fold. First, the pathophysiology of bone fragil...

Low dose IL-2 suppress osteoclastogenesis in collagen-induced arthritis via JNK dependent pathway.

Oct 26, 2020

Rheumatoid arthritis (RA) is one of the most common chronic immune joint diseases, mainly involving blood vessels and small joints. The complex pathogenesis of RA greatly increases the difficulty of t...

Greater Conditioned Pain Modulation Is Associated With Enhanced Morphine Analgesia in Healthy Individuals and Patients with Chronic Low Back Pain.

Oct 22, 2020

Conditioned pain modulation (CPM) protocols index magnitude of descending pain inhibition. This study evaluated whether degree of CPM, controlling for CPM expectancy confounds, was associated with ana...

Tooth Development Following Mandibular Distraction Osteogenesis in Neonates With Pierre Robin Sequence.

Oct 22, 2020

Mandibular distraction osteogenesis is a widely utilized surgical procedure in the pediatric population for the treatment of mandibular retrognathia. Patients with congenital abnormalities may display...

Variable Fixation Technology Provides Rigid as Well as Progressive Dynamic Fixation: A Biomechanical Investigation.

Oct 22, 2020

A new locking-screw technology, the Variable Fixation Locking Screw (VFLS; Biomech Innovations), was developed with the aim of promoting secondary fracture-healing. The VFLS features a resorbable slee...

An Assessment of Randomized Controlled Trial Quality in The Journal of Bone & Joint Surgery: Update from 2001 to 2013.

Oct 22, 2020

The quality of reporting of randomized controlled trials (RCTs) published in The Journal of Bone & Joint Surgery (JBJS) from 1988 to 2000 was previously analyzed. The purpose of this current study...

Publishing Characteristics of Foot and Ankle Research Over a 15-Year Time Interval: A Review of The Journal of Bone & Joint Surgery from 2004 to 2018.

Oct 22, 2020

As the foot and ankle subspecialty continues to grow in orthopaedics, trends in published literature provide valuable insights to help understand and strengthen the field. The current study evaluates ...

Patterns of pediatric cervical spine fractures in association with mandibular and facial fractures.

Oct 15, 2020

To determine the incidence, demographics, and outcomes of concurrent cervical spine (C-spine) fractures in pediatric facial trauma.The Kids' Inpatient Database (KID) from the 2016 Healthcare Cost Util...

Eight-Week Inspiratory Muscle Training Alters Electromyography Activity of the Ankle Muscles During Overhead and Single-Leg Squats: A Randomized Controlled Trial.

Oct 15, 2020

This study was conducted to evaluate the effects of 8-week inspiratory muscle training on activity in the ankle muscles of athletes with chronic low-back pain. A randomized controlled trial involving ...

A Comparison of Clinical Spinal Mobility Measures to Experimentally Derived Lumbar Spine Passive Stiffness.

Oct 15, 2020

Spinal stiffness and mobility assessments vary between clinical and research settings, potentially hindering the understanding and treatment of low back pain. A total of 71 healthy participants were e...

Classification of various sources of error in range assessment using proton radiography and neural networks in head and neck cancer patients.

Oct 15, 2020

This study evaluates the suitability of convolutional neural networks (CNN) to automatically process proton radiography (PR) based images. CNNs are used to classify PR images impaired by several sourc...

Click chemistry based biopolymeric hydrogels for regenerative medicine.

Oct 15, 2020

Click chemistry is not a single specific reaction, but describes ways of generating products following examples in nature. Click reactions occur in one pot, are not disturbed by water, generate minima...

Crosstalk between CML cells with HUVECS and BMSCs through CML derived exosomes.

Oct 15, 2020

Chronic Myeloid Leukemia (CML) is a myeloproliferative neoplasm characterized by presence of the BCR-ABL fusion gene which encodes the constitutively active BCR-ABL chimeric protein. Imatinib is first...

Functional outcome of gastrocnemius advancement flap augmented with short flexor hallucis longus tendon transfer in chronic Achilles tear.

Oct 12, 2020

There are various techniques of Achilles tendon (TA) repair and reconstruction in chronic Achilles tear. However, there is no clear consensus on the relevance of one method over the other. The short f...

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